ID A0A0K9PVB3_ZOSMR Unreviewed; 1674 AA.
AC A0A0K9PVB3;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Brefeldin A-inhibited guanine nucleotide-exchange protein 1 {ECO:0000313|EMBL:KMZ72177.1};
GN ORFNames=ZOSMA_16G01480 {ECO:0000313|EMBL:KMZ72177.1};
OS Zostera marina (Eelgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Zosteraceae; Zostera.
OX NCBI_TaxID=29655 {ECO:0000313|EMBL:KMZ72177.1, ECO:0000313|Proteomes:UP000036987};
RN [1] {ECO:0000313|Proteomes:UP000036987}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Finnish {ECO:0000313|Proteomes:UP000036987};
RX PubMed=26814964; DOI=10.1038/nature16548;
RA Olsen J.L., Rouze P., Verhelst B., Lin Y.-C., Bayer T., Collen J.,
RA Dattolo E., De Paoli E., Dittami S., Maumus F., Michel G., Kersting A.,
RA Lauritano C., Lohaus R., Toepel M., Tonon T., Vanneste K., Amirebrahimi M.,
RA Brakel J., Bostroem C., Chovatia M., Grimwood J., Jenkins J.W.,
RA Jueterbock A., Mraz A., Stam W.T., Tice H., Bornberg-Bauer E., Green P.J.,
RA Pearson G.A., Procaccini G., Duarte C.M., Schmutz J., Reusch T.B.H.,
RA Van de Peer Y.;
RT "The genome of the seagrass Zostera marina reveals angiosperm adaptation to
RT the sea.";
RL Nature 530:331-335(2016).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMZ72177.1}.
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DR EMBL; LFYR01000643; KMZ72177.1; -; Genomic_DNA.
DR STRING; 29655.A0A0K9PVB3; -.
DR OMA; LNFKGMD; -.
DR OrthoDB; 296747at2759; -.
DR Proteomes; UP000036987; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005802; C:trans-Golgi network; IBA:GO_Central.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR032629; DCB_dom.
DR InterPro; IPR015403; Mon2/Sec7/BIG1-like_HDS.
DR InterPro; IPR032691; Mon2/Sec7/BIG1-like_HUS.
DR InterPro; IPR046455; Sec7/BIG1-like_C.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663:SF108; BREFELDIN A-INHIBITED GUANINE NUCLEOTIDE-EXCHANGE PROTEIN 1; 1.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF20252; BIG2_C; 1.
DR Pfam; PF16213; DCB; 1.
DR Pfam; PF01369; Sec7; 1.
DR Pfam; PF09324; Sec7-like_HDS; 1.
DR Pfam; PF12783; Sec7-like_HUS; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000036987};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 534..721
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
SQ SEQUENCE 1674 AA; 187531 MW; 39D2851683CD58AA CRC64;
MASSAQTVGG KSRAGRIIGP SLDRIIKNVP WRKHSNLVAS CKSALDKLQT LVISDPNVTD
ISTSLHIHGL SESDADFVIG PIFLALDTNS PKLIEPALDC LQKLFSHGVF RGEVEPGEAN
LAGRLVEGVC KCDGSGDDAI EIGVIRVVIA AVRSRVVLLK GECLVDLVKS LCNVCLGSHS
ISNRVCAKSV LVQLVLIVFR RVEIGKMEVE VDVVQIEDIL DLSDKSLNDS TVVNSAQGFI
REVMGGNAVD ESELLRLRVE NGKADCEDSD LEIVSKIRED GLFLFKNLCK FSMKFSTQEN
REDHLLVRGK LLSLELLKIV IDNSGQIWKT DDKFIGVIKQ YLCLSILKNS GLTVMSISQL
LCSLFICLLS KFRSGLKKEI GFFFPVLFLR VLENVLQPSY LQKLTVLNLL EKIFQDPQII
IDVFVNYDCD VDAPNIFERT VNALLKTALG VPPGSATSLT PAQDMTFRLE SVKCLTCIIK
SMGTWMDQQL RIGDFCPKTP EIDTPTETTS GEDGPGIDFE LHSDMNSGLF DTLTLEQRRI
YKIELLKGIS LFNRKPYKGI EFLISTKKIG GSPEEVASFL RNTNGLNETM IGDYLGDRDE
FPLKIMHAYV DSFNFEGIDF GEAIRVFLRG FRLPGEAQKI DRIMEKFAER YCKCNPSSFT
SADTAYVLAY SVIMLNTDAH NNMVKDKMSK SDFIRNNRGI DDGKDLPEDY LGSLYDHIVK
NEIKMKADPS APQHKQANSI NKLLGLDAIL NLVWKQPQEK PLGANDLLIK HIQDQFKAKT
GKSEPVFYTV MDATILRFMM ESCWAPMMAA FSVTLDQSDD TAATFQCLQG FRFAVHVTSV
MSMQTQRDAF VTSVAKFTYL HNAADMKQKN FDAVKAIMSI AIEDGNHLQE AWEHVLTCLS
RFEHLQLLGE GAPTDASFFM VSNNDTEEKS QKTPVIQNLK KKGHALQSSS VMAVMRGGSY
DSTAVGINSS GLVSPEQINN FISNLNLLDQ MGNFELSHIF AHSQRLNSEA IVAFVMALCK
VSMAELQSPT DPRVFSLTKI VEIAVLSDFF VAVGISENLS VAIFVMDSLR QLAMKFLERE
ELANYNFQNE FLRPFAIVMQ KSSCVEIREL IVRCVSQMVL TRVNHVKSGW KSVFMVFTTA
AADERKNIVQ LAFETMEKIV RDYFPYITET ETTTFTDCVR CLTTFTNSKF NSDVSLNAIA
FLRFCAVKLA EGGLVCYDKN TEYDSVNEET SNNDTCMDYW TPLLDGLSTL TSDSRSAIRK
GSLEVLFNIL KDHGHLFSHT FWKNVFHSFI FPIFSDSRLI NYNLESSQWS DSTKHEEYVW
SSETQTVAAQ CLVDLYVNFF EMVRNVLPDI VSILMSFIRS PYNSSTNIGV TALLRLTRYL
GNKFTELEWS EILEALKVTS SSTFSEFSKI VRTMESLEIP RVIPPDSDAE LYSENELDNS
EPEENDMEAA SYSVARMKGH IAVQLLLGQA VTSLNMEHSN SLSASHIKIL LEILSSITEH
ASKLVIETTL QLKFQRTCTH LDISEPPLIH FENESYQSYL GLLQTLLVEK PSVSEEIGAE
DEIVVVCKKI LQMYLNCAEL KSTIHQDLNS DKRALHLIIP LGSAKREELA ARTTLVVHSM
HVLNNFERNS FRRYVSCLFP LLVNLVRCEH SSSEVQEVLS EIFRSSIGPI VLNP
//
