ID A0A0K9Q2H0_ZOSMR Unreviewed; 1443 AA.
AC A0A0K9Q2H0;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=SEC7-like guanine nucleotide exchange family protein {ECO:0000313|EMBL:KMZ74687.1};
GN ORFNames=ZOSMA_123G00350 {ECO:0000313|EMBL:KMZ74687.1};
OS Zostera marina (Eelgrass).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Zosteraceae; Zostera.
OX NCBI_TaxID=29655 {ECO:0000313|EMBL:KMZ74687.1, ECO:0000313|Proteomes:UP000036987};
RN [1] {ECO:0000313|Proteomes:UP000036987}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Finnish {ECO:0000313|Proteomes:UP000036987};
RX PubMed=26814964; DOI=10.1038/nature16548;
RA Olsen J.L., Rouze P., Verhelst B., Lin Y.-C., Bayer T., Collen J.,
RA Dattolo E., De Paoli E., Dittami S., Maumus F., Michel G., Kersting A.,
RA Lauritano C., Lohaus R., Toepel M., Tonon T., Vanneste K., Amirebrahimi M.,
RA Brakel J., Bostroem C., Chovatia M., Grimwood J., Jenkins J.W.,
RA Jueterbock A., Mraz A., Stam W.T., Tice H., Bornberg-Bauer E., Green P.J.,
RA Pearson G.A., Procaccini G., Duarte C.M., Schmutz J., Reusch T.B.H.,
RA Van de Peer Y.;
RT "The genome of the seagrass Zostera marina reveals angiosperm adaptation to
RT the sea.";
RL Nature 530:331-335(2016).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMZ74687.1}.
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DR EMBL; LFYR01000252; KMZ74687.1; -; Genomic_DNA.
DR STRING; 29655.A0A0K9Q2H0; -.
DR OMA; CMDGFIA; -.
DR OrthoDB; 204547at2759; -.
DR Proteomes; UP000036987; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0051641; P:cellular localization; IEA:UniProt.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProt.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR032691; Mon2/Sec7/BIG1-like_HUS.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663:SF388; GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1; 1.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF01369; Sec7; 1.
DR Pfam; PF12783; Sec7-like_HUS; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW Reference proteome {ECO:0000313|Proteomes:UP000036987}.
FT DOMAIN 534..723
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
SQ SEQUENCE 1443 AA; 162498 MW; 2A5A160994C207A0 CRC64;
MGRMKFPPPI EEAVEDHGGG WNTRATLPCM INSEIGTVLA VMRRNVRWGG HYMGDENQLE
HPLVQSLKTL RNQMFAWDQQ WHTIDPVNYL QPFLDVIQSD ETGAPITGVA LSSVYKIVTL
DILNLNTVNI DKAMPLIADS VTSCRFEVTD PASEEVVLMK ILQVLLACMK SKASVVLSNQ
HVCNIVSTCF RVVNQAGSKG ELLQRISRHT MHELIRCIIS RLHNVENQSS LTEDGLFLKS
ELGRLDRDPA FGIMQVENGN GSLDTPGEAS SVDENGMVSK HDSVVQLMSG PFGLPCIVEI
FHFLCSLLNI SEHIEMGPRS NPVTYEEDMP LFALGLINSA IELAGPSIRI HLQLLSLVKD
ELFYNLMQLG LSTSPLIISM VCNIVLNLYH HLHSELKLQI EAFFSCVILR LAKNRHGASY
QQQEVAMEAL VDFCRQKNFM AEMYANLDCE ITCDNTFEEL VNLLSQSAFP VNSPLSAMHI
LALDGLIAIV KGMVSRINKS PQILDEVPFK LERYTPFWTA KCDNYSDPNH WVQYIRHRKY
IKKKLMAGVD HFNREPNKGL EFLQGIHLLP EKLDPHSVAC FFHYTSGLDK NYVGEFLGNH
DEFCIRVLHE FAKIFDFQDM NLDTALRLFL DTFRLPGESQ KIQRVLEAFS ERYYEQSPHI
LANKDAALLL SYSLIMLNTD QHNVQVKKKM TKEDFIRNNR HINGGNDLPR EYLSELYHAI
CKNELKTIPE QGAGFPEMTP SHWIDIMQKS KKTSPYIFCN SLPFLDQDMF AIMCGPTIAA
ISVVFDYAEH DEVFHSCIEG FLVLAKLSAS YHLGDVLDDL VTSLCRFTTL TNSSSVDEPA
MEFGDDLKAR LATEAVFNLA NQYGDFIRIG WRGILDCILR LNKLGFLPAR VASDATSDEY
DTSADTEHGK LNSQITSQAP IIVNLRKPSG LMGRFSQLLS LDTEEPRSQP TEQQIAAHNC
TIQTIQKCHI DSIFTESKFL QADSLLNLVH ALISAAAQIQ KDNGLLDDED IAVFCLELLI
AITLNNRDRI VILWQSVYDH IASIVQSTSI PSPLVEKAVF GLLKICQRLL PYKENLADEL
MRSLQLILKL DARVADAYCE NITHEVTRLV KTNATHIKSP VGWRTITSLL SITARHPEAS
ECGFEALLFI MSDGAHLSPA NYILCIEAAR QFAQSRVGLA VRSVRALDLM AESVRCLVRW
SLDTKDAKEG AEKISQGLQE MWLRLVHGLK KVCLDQRDEV RNHALSLLQR CMVGVEDIRL
SPESWLQCFD TVIFTLLDEL LDIVQGQSRN EYRNMETSLV LAMKLLSKVF LQSLEDLAPL
SSFIELWASF LSQMEKYIKV KIRSRRSEKL QELIPELLKN TLLVMKAGRI LNNKAPISAA
DNLWELTWVH VNDIVPSLKT EVLSIEELAQ DAAAIVVDKD AKEAKKRTES GHALSLDEGI
QAA
//
