ID A0A0K9XKS6_9ACTN Unreviewed; 598 AA.
AC A0A0K9XKS6;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Chloride channel protein {ECO:0000313|EMBL:KNB53955.1};
GN ORFNames=AC230_05170 {ECO:0000313|EMBL:KNB53955.1};
OS Streptomyces caatingaensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1678637 {ECO:0000313|EMBL:KNB53955.1, ECO:0000313|Proteomes:UP000037288};
RN [1] {ECO:0000313|Proteomes:UP000037288}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CMAA 1322 {ECO:0000313|Proteomes:UP000037288};
RA Santos S.N., Gacesa R., Taketani R.G., Long P.F., Melo I.S.;
RT "Draft genome sequence of Streptomyces sp. CMAA 1322, a bacterium isolated
RT from Caatinga biome, from dry forest semiarid of Brazil.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNB53955.1}.
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DR EMBL; LFXA01000002; KNB53955.1; -; Genomic_DNA.
DR RefSeq; WP_049714693.1; NZ_LFXA01000002.1.
DR AlphaFoldDB; A0A0K9XKS6; -.
DR STRING; 1678637.AC230_05170; -.
DR PATRIC; fig|1678637.3.peg.1125; -.
DR OrthoDB; 9767361at2; -.
DR Proteomes; UP000037288; Unassembled WGS sequence.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd02205; CBS_pair_SF; 1.
DR CDD; cd00400; Voltage_gated_ClC; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR PANTHER; PTHR43427:SF6; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SMART; SM00116; CBS; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 2.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000037288};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 75..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 209..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 245..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 319..337
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 343..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 368..387
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 407..425
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 459..522
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 528..586
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 598 AA; 62131 MW; B1E64188F6E72D61 CRC64;
MSGHHPAPPS PATTGLGDFT TRPRALLVVA WALPVGAAGA VASWFLLRLI GLIGNLVFRQ
RLGTELVDPG RVHPAWWLVL GAPVLGGLAV GLLARHGSEK IRGHGMPEAI EAILTRGGVV
APRLALLKPL SAAISIGTGG PFGAEGPVIM TGGAIGSLFG QSLRLTAAER RTLLVAGSAA
GMAATFDAPM ASVLLAVELL LFEWRPRSLV PVVASVAVAT ALRVPLLGGG PVFPVDAAAV
HLTPLVELLA VLCGLTGGAL AVVTTWMVYR AEDAFARLPF HWMWWPALGG LVIGCGGLVE
PRALGVGYDV VQQLLAGRAT VSLIVGVLVV KSLIWALSLG SGTSGGVLAP VLMIGGALGA
WEGMLFPSVV PGFWAMLGLA AVVGGVLRSP LTGVVFTLEL THAWDTGPAL LISATSAYAL
SVLVLKRSLL TEKIARRGLH LTREYATDPL EAFFVREAMD AAPSTVGADD PLDGALAAAC
AERLRSPDRP QRLIPVLRPD GGLLGIITRR SLRAARAGGG TLTAADAARP CRLTVRGDDT
LRRVACLFAE HALTSAPVVD PATGRPIGVI ALRDLLHARR HQLVQEGHRE RVIRPAGR
//
