ID A0A0L0AEC1_9ENTR Unreviewed; 391 AA.
AC A0A0L0AEC1;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Multidrug transporter {ECO:0000313|EMBL:KNC06090.1};
GN ORFNames=AC791_19290 {ECO:0000313|EMBL:KNC06090.1};
OS Klebsiella sp. RIT-PI-d.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX NCBI_TaxID=1681196 {ECO:0000313|EMBL:KNC06090.1, ECO:0000313|Proteomes:UP000053401};
RN [1] {ECO:0000313|Proteomes:UP000053401}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RIT-PI-d {ECO:0000313|Proteomes:UP000053401};
RA Tan N.E.H., Lee Y.P., Gan H.M., Savka M.A.;
RT "Whole genome sequencing of endophytes isolated from poison ivy
RT (Toxicodendron radicans).";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNC06090.1}.
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DR EMBL; LGIT01000018; KNC06090.1; -; Genomic_DNA.
DR RefSeq; WP_049842101.1; NZ_LGIT01000018.1.
DR AlphaFoldDB; A0A0L0AEC1; -.
DR STRING; 1681196.AC791_19290; -.
DR PATRIC; fig|1681196.3.peg.3946; -.
DR OrthoDB; 9811754at2; -.
DR Proteomes; UP000053401; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1990961; P:xenobiotic detoxification by transmembrane export across the plasma membrane; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR005694; MFP_proteobact.
DR NCBIfam; TIGR00998; 8a0101; 1.
DR PANTHER; PTHR30386; MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP; 1.
DR PANTHER; PTHR30386:SF19; MULTIDRUG EXPORT PROTEIN EMRA-RELATED; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 2.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022519};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053401};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 24..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 47..347
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
FT DOMAIN 199..290
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 391 AA; 43056 MW; E1B8E9F68891A8E4 CRC64;
MSENAEIQTP QQPVNKKKGK RKRLLLLLTL LFVIIAVVWG IYWFLVLRHF EETDDAYVAG
NQVQIMAQVS GSVTKVWADN TDFVQKGDVL VTLDQTDAQQ AFEKAQTGLA SSVRQTRQQM
INSQQLQANI NVQKTALSQA QTDLNRRVPL GSANLIGREE LQHARDAVAS AQAKLDVAIQ
QYNANQAIIL GTRLEDQPAV KQAATEVRNA WLALQRTKIV SPMTGYVSRR SVQPGAQISP
TTPLMAVVPA TNLWVDANFK ETQLAHMRIG QSVTVVSDIY GDDVKYTGTV VGLDMGTGSA
FSLLPAQNAT GNWIKVVQRL PVRIELDQKQ LTDHPLRIGL STLVTVDTTN RDGQMLANQV
RKDPAYESNA REISLEPVNK LINDIVQANA G
//
