ID A0A0L0BKY9_LUCCU Unreviewed; 485 AA.
AC A0A0L0BKY9;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Aldehyde dehydrogenase domain-containing protein {ECO:0000259|Pfam:PF00171};
GN ORFNames=FF38_00444 {ECO:0000313|EMBL:KNC20598.1};
OS Lucilia cuprina (Green bottle fly) (Australian sheep blowfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Oestroidea;
OC Calliphoridae; Luciliinae; Lucilia.
OX NCBI_TaxID=7375 {ECO:0000313|EMBL:KNC20598.1, ECO:0000313|Proteomes:UP000037069};
RN [1] {ECO:0000313|EMBL:KNC20598.1, ECO:0000313|Proteomes:UP000037069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LS {ECO:0000313|EMBL:KNC20598.1,
RC ECO:0000313|Proteomes:UP000037069};
RC TISSUE=Full body {ECO:0000313|EMBL:KNC20598.1};
RX PubMed=26108605; DOI=10.1038/ncomms8344;
RA Anstead C.A., Korhonen P.K., Young N.D., Hall R.S., Jex A.R., Murali S.C.,
RA Hughes D.S., Lee S.F., Perry T., Stroehlein A.J., Ansell B.R.,
RA Breugelmans B., Hofmann A., Qu J., Dugan S., Lee S.L., Chao H., Dinh H.,
RA Han Y., Doddapaneni H.V., Worley K.C., Muzny D.M., Ioannidis P.,
RA Waterhouse R.M., Zdobnov E.M., James P.J., Bagnall N.H., Kotze A.C.,
RA Gibbs R.A., Richards S., Batterham P., Gasser R.B.;
RT "Lucilia cuprina genome unlocks parasitic fly biology to underpin future
RT interventions.";
RL Nat. Commun. 6:7344-7344(2015).
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNC20598.1}.
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DR EMBL; JRES01001712; KNC20598.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L0BKY9; -.
DR STRING; 7375.A0A0L0BKY9; -.
DR EnsemblMetazoa; KNC20598; KNC20598; FF38_00444.
DR OMA; RRMDTGQ; -.
DR Proteomes; UP000037069; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR11699:SF269; ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL-LIKE PROTEIN; 1.
DR PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000037069}.
FT DOMAIN 19..480
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 257
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 485 AA; 52963 MW; C62BE0B64FFB9884 CRC64;
MANPQLEPKY TKLFINNEFV DAKSGKTFPT YNPATEKVIA QVAEGDKADV DLAVEAAKKA
FHRNSAWRKM SPLQRTELMM KLCELMEREK NLLASLESLD NGKPFAEALF DVEISIMTLK
YYAGWTDKFF GDTIPAGGFI SMTKKEPIGV VGQIIPWNYP LLMLSWKWGP ALAVGCTIVM
KPAEQTPLTA LHMAALAKEA GFPPGVINII TGYGPTAGAA ISEHPEIRKV AFTGSVDIGR
VVMEAAAKSN LKRVSLELGG KSPIFVFDDT NVDLAVDICH DALFSNHGQS CCAGSRTYVH
EKIYDEFVAK AAAKAKARKV GNPFDESVLQ GPQIDKEMLT KVLGFIESGK QEGAKLQCGG
KRIGDVGFFV EPTVFSDVKD DMKIAQEEIF GPVQSIFKFS SVDEIIERAN NVKYGLAAGV
ITNDINKAMH FSNNVDAGSV WINCYDAVLP QTPFGGYKQS GMGRELGKDG LDNYLETKTI
TMKLV
//
