ID A0A0L0BTS3_LUCCU Unreviewed; 415 AA.
AC A0A0L0BTS3;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Endoplasmic reticulum-Golgi intermediate compartment protein 2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=FF38_04773 {ECO:0000313|EMBL:KNC23485.1};
OS Lucilia cuprina (Green bottle fly) (Australian sheep blowfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Oestroidea;
OC Calliphoridae; Luciliinae; Lucilia.
OX NCBI_TaxID=7375 {ECO:0000313|EMBL:KNC23485.1, ECO:0000313|Proteomes:UP000037069};
RN [1] {ECO:0000313|EMBL:KNC23485.1, ECO:0000313|Proteomes:UP000037069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LS {ECO:0000313|EMBL:KNC23485.1,
RC ECO:0000313|Proteomes:UP000037069};
RC TISSUE=Full body {ECO:0000313|EMBL:KNC23485.1};
RX PubMed=26108605; DOI=10.1038/ncomms8344;
RA Anstead C.A., Korhonen P.K., Young N.D., Hall R.S., Jex A.R., Murali S.C.,
RA Hughes D.S., Lee S.F., Perry T., Stroehlein A.J., Ansell B.R.,
RA Breugelmans B., Hofmann A., Qu J., Dugan S., Lee S.L., Chao H., Dinh H.,
RA Han Y., Doddapaneni H.V., Worley K.C., Muzny D.M., Ioannidis P.,
RA Waterhouse R.M., Zdobnov E.M., James P.J., Bagnall N.H., Kotze A.C.,
RA Gibbs R.A., Richards S., Batterham P., Gasser R.B.;
RT "Lucilia cuprina genome unlocks parasitic fly biology to underpin future
RT interventions.";
RL Nat. Commun. 6:7344-7344(2015).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Endoplasmic reticulum-Golgi
CC intermediate compartment membrane {ECO:0000256|ARBA:ARBA00004457};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004457}.
CC -!- SIMILARITY: Belongs to the ERGIC family.
CC {ECO:0000256|ARBA:ARBA00005648}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNC23485.1}.
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DR EMBL; JRES01001349; KNC23485.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L0BTS3; -.
DR STRING; 7375.A0A0L0BTS3; -.
DR EnsemblMetazoa; KNC23485; KNC23485; FF38_04773.
DR OMA; GQIMFLV; -.
DR Proteomes; UP000037069; Unassembled WGS sequence.
DR GO; GO:0033116; C:endoplasmic reticulum-Golgi intermediate compartment membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046907; P:intracellular transport; IEA:UniProt.
DR InterPro; IPR045888; Erv.
DR InterPro; IPR012936; Erv_C.
DR InterPro; IPR039542; Erv_N.
DR PANTHER; PTHR10984; ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN; 1.
DR PANTHER; PTHR10984:SF30; ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 2; 1.
DR Pfam; PF07970; COPIIcoated_ERV; 1.
DR Pfam; PF13850; ERGIC_N; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000037069};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 324..346
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 19..104
FT /note="Endoplasmic reticulum vesicle transporter N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF13850"
FT DOMAIN 174..342
FT /note="Endoplasmic reticulum vesicle transporter C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF07970"
SQ SEQUENCE 415 AA; 47377 MW; E9F49CF50F99319D CRC64;
MSATLRYRGD KNNLIELAKN LDAFKKVPEK YTETTEIGGT LSLISRLLII FLIYKEVLYY
KDAKLKYQFE PDIDTEKVQM HVDITVAMPC SSLSGVDLMD ETQQDVFAYG TLQRQGVWWQ
MSPDERVEFE RQQYMNHYRR EQYHSIADIL FKDMIKSNEA HEQPLGDNGK PVPEDQYDAC
RLHGTLGINK VAGVLHLVGG AMPVVDLFGD HLMIGFRRMP ANFTHRINRL SFGQYSKHIV
QPLEGDEVYI TEEETTIQYF LNIVPTEIHN TFTTINTYQY SVTENKRVLD PVQNSYGNPG
IYFKYDWSAL RIIVRTDRDN LIQFIIRLCS IIAGIIVISG ILNYILVSVQ KCLLQTFAPQ
LLHKRLKETP EHSPLAAAPV ALPTPVVVTN DLISNANKMS AQVTAILPTN SNLKE
//
