ID A0A0L0BUG3_LUCCU Unreviewed; 649 AA.
AC A0A0L0BUG3;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 22-FEB-2023, entry version 25.
DE SubName: Full=Heat shock 70 kDa protein cognate 1 {ECO:0000313|EMBL:KNC23682.1};
DE Flags: Fragment;
GN ORFNames=FF38_00809 {ECO:0000313|EMBL:KNC23682.1};
OS Lucilia cuprina (Green bottle fly) (Australian sheep blowfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Oestroidea;
OC Calliphoridae; Luciliinae; Lucilia.
OX NCBI_TaxID=7375 {ECO:0000313|EMBL:KNC23682.1, ECO:0000313|Proteomes:UP000037069};
RN [1] {ECO:0000313|EMBL:KNC23682.1, ECO:0000313|Proteomes:UP000037069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LS {ECO:0000313|EMBL:KNC23682.1,
RC ECO:0000313|Proteomes:UP000037069};
RC TISSUE=Full body {ECO:0000313|EMBL:KNC23682.1};
RX PubMed=26108605; DOI=10.1038/ncomms8344;
RA Anstead C.A., Korhonen P.K., Young N.D., Hall R.S., Jex A.R., Murali S.C.,
RA Hughes D.S., Lee S.F., Perry T., Stroehlein A.J., Ansell B.R.,
RA Breugelmans B., Hofmann A., Qu J., Dugan S., Lee S.L., Chao H., Dinh H.,
RA Han Y., Doddapaneni H.V., Worley K.C., Muzny D.M., Ioannidis P.,
RA Waterhouse R.M., Zdobnov E.M., James P.J., Bagnall N.H., Kotze A.C.,
RA Gibbs R.A., Richards S., Batterham P., Gasser R.B.;
RT "Lucilia cuprina genome unlocks parasitic fly biology to underpin future
RT interventions.";
RL Nat. Commun. 6:7344-7344(2015).
CC -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC {ECO:0000256|ARBA:ARBA00007381, ECO:0000256|RuleBase:RU003322}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNC23682.1}.
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DR EMBL; JRES01001310; KNC23682.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L0BUG3; -.
DR STRING; 7375.A0A0L0BUG3; -.
DR EnsemblMetazoa; KNC23682; KNC23682; FF38_00809.
DR OMA; VNEAESY; -.
DR Proteomes; UP000037069; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR CDD; cd10233; HSPA1-2_6-8-like_NBD; 1.
DR Gene3D; 1.20.1270.10; -; 1.
DR Gene3D; 3.30.30.30; -; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR018181; Heat_shock_70_CS.
DR InterPro; IPR029048; HSP70_C_sf.
DR InterPro; IPR029047; HSP70_peptide-bd_sf.
DR InterPro; IPR013126; Hsp_70_fam.
DR PANTHER; PTHR19375:SF395; HEAT SHOCK 70 KDA PROTEIN COGNATE 1-RELATED; 1.
DR PANTHER; PTHR19375; HEAT SHOCK PROTEIN 70KDA; 1.
DR Pfam; PF00012; HSP70; 1.
DR PRINTS; PR00301; HEATSHOCK70.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR SUPFAM; SSF100934; Heat shock protein 70kD (HSP70), C-terminal subdomain; 1.
DR SUPFAM; SSF100920; Heat shock protein 70kD (HSP70), peptide-binding domain; 1.
DR PROSITE; PS00297; HSP70_1; 1.
DR PROSITE; PS00329; HSP70_2; 1.
DR PROSITE; PS01036; HSP70_3; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003322};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003322};
KW Reference proteome {ECO:0000313|Proteomes:UP000037069};
KW Stress response {ECO:0000313|EMBL:KNC23682.1}.
FT REGION 622..649
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 516..547
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KNC23682.1"
SQ SEQUENCE 649 AA; 71357 MW; 7F08FAEC535C4278 CRC64;
RFTFIFLKMA KVPAVGIDLG TTYSCVGVFQ HGKVEIIAND QGNRVTPSYV AFTDTERLIG
DAAKNQVAMN PNNTIFDAKR LIGRKFEDAT VQSDMKHWPF EVVSDGGKPK IRVEYKGEKK
TFFPEEVSSM VLTKMKETAE AYLGRSVTDA VVTVPAYFND SQRQATKDAG AIAGLNVLRI
INEPTAAAIA YGLDKKGTSE RNVLIFDLGG GTFDVSILTI EDGIFEVKST AGDTHLGGED
FDNRMVNHFV QEFQRKHKKD LASNKRALRR LRTACERAKR TLSASSQASI EIDSLFDGID
FYTSITRARF EELNGDLFRG TMEPVAKALR DAKMDKGQIH DIVLVGGSTR IPRVQKLLQD
FFNGKELNKS INPDEAVAYG AAVQAAILHG DKSEAVQDLL LLDVTPLSLG IEAAGGVMTV
LIKRNTTIPT KQTQVFTTYS DNQPGVLIQV FEGERAMTKD NNILGKFELS GIPPAPRGVP
QIEVTFDIDA NGILNVTAVE KSTGKENKIT ITNDKGRLAK EDIERMVNEA EAYRNEDEKQ
RERINAKNAL ESYCFQMKST IDDDNIKAKV SESDRKLIMD KCNETISWLD GNQQAEKEEY
EYKQKELQNI CNPIITRLYQ GGAAPPPGGM PGAGGAGPSG GGPTIEEVD
//
