ID A0A0L0C139_LUCCU Unreviewed; 1194 AA.
AC A0A0L0C139;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Anaphase-promoting complex subunit 4-like WD40 domain-containing protein {ECO:0000259|Pfam:PF12894};
GN ORFNames=FF38_08327 {ECO:0000313|EMBL:KNC25972.1};
OS Lucilia cuprina (Green bottle fly) (Australian sheep blowfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Oestroidea;
OC Calliphoridae; Luciliinae; Lucilia.
OX NCBI_TaxID=7375 {ECO:0000313|EMBL:KNC25972.1, ECO:0000313|Proteomes:UP000037069};
RN [1] {ECO:0000313|EMBL:KNC25972.1, ECO:0000313|Proteomes:UP000037069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LS {ECO:0000313|EMBL:KNC25972.1,
RC ECO:0000313|Proteomes:UP000037069};
RC TISSUE=Full body {ECO:0000313|EMBL:KNC25972.1};
RX PubMed=26108605; DOI=10.1038/ncomms8344;
RA Anstead C.A., Korhonen P.K., Young N.D., Hall R.S., Jex A.R., Murali S.C.,
RA Hughes D.S., Lee S.F., Perry T., Stroehlein A.J., Ansell B.R.,
RA Breugelmans B., Hofmann A., Qu J., Dugan S., Lee S.L., Chao H., Dinh H.,
RA Han Y., Doddapaneni H.V., Worley K.C., Muzny D.M., Ioannidis P.,
RA Waterhouse R.M., Zdobnov E.M., James P.J., Bagnall N.H., Kotze A.C.,
RA Gibbs R.A., Richards S., Batterham P., Gasser R.B.;
RT "Lucilia cuprina genome unlocks parasitic fly biology to underpin future
RT interventions.";
RL Nat. Commun. 6:7344-7344(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNC25972.1}.
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DR EMBL; JRES01001049; KNC25972.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L0C139; -.
DR STRING; 7375.A0A0L0C139; -.
DR EnsemblMetazoa; KNC25972; KNC25972; FF38_08327.
DR OMA; HCASPME; -.
DR Proteomes; UP000037069; Unassembled WGS sequence.
DR GO; GO:0060271; P:cilium assembly; IEA:InterPro.
DR Gene3D; 1.25.40.470; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR039857; Ift122/121.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR017233; WDR35.
DR PANTHER; PTHR12764:SF5; LD29485P; 1.
DR PANTHER; PTHR12764; WD REPEAT DOMAIN-RELATED; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR Pfam; PF00400; WD40; 1.
DR PIRSF; PIRSF037536; WD_repeat_p35; 1.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF48452; TPR-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000037069};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 67..98
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 130..213
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
SQ SEQUENCE 1194 AA; 134248 MW; A15ACF22EFB71605 CRC64;
MFVYLSKKIA IPNNVKLNCI SWNKEQGYIA VAGTDGLLKV LKLEQASNGQ NKGGLAAVSN
LSMNQTLDGH KDAVKVVVWN DAQQKLTSSD VDGVIMVWML YKGSWYEEMT NDRKKSTVNG
MHWTSDGSKI CIVYEDGAII VGSVDGNRIW GKELKNTHLS GVQWSPDNRL LLFSLANGEC
HLYDNQGNFA MKLNIQCVAL NVNRHNSVTA LSWFSGKSPP NRPVLAICYE SGKVQIMIDE
NDEAPTILNT HMHITDAKWN HDGSVLAICG RLDEVSNTKE LNQVSFYSPY GHLYRTLKVP
GNQITSISWE GKSLRIAMAV DSFIYFANIR PDYRWCYFEK TVVFLSERSN GKTNNLNLIT
FWNTSSNQSF LKEVEACLGM AACNEHCVLA VECISGNIKD LALTSLERKN ADDKLYQLLL
CNSIGTTVDS KYTEVCPNFI GINSNYVAIA SKDEILLWHY HTPKSASQLH NVKSRKEKRF
HIDDTPTGID LAKDLVVSRT SQDNAEINTD LICSLAVSEK ILLVARESGL INEYSIPNVA
LRNRHKIGSK IIKMSINCNS SRAALIDSNG VMTLLDLDDN RETQLNFSRV ERKDVWAICW
AKDNPLLLAL MEKTRMYIFR GNDPEEPVAC SGYICTFEDL EITSVLLDDI ISGEESQNSL
SHILQLKVKS LRDTDDLLQH VGLEDAKQFI EDNPHPRLWR LLAEAALKKL ELDIAENAFV
RCSNYQGIQL VKRLRTIPSE MLQKAEIAAF YGEFEEAEKL YIDGDRRDLA INLRITLCDW
FRVVQLYRMG SGISDQQMET AWRQIGHHFA SLRSWESAKE YYDKSHDIEG LMESLYHLEQ
FEELEKCIDK LPEKSPLLSK IAEMLASVGM CSEAVNAYLK LGDPKSAVNT CVNLRQWGQA
VELAQKFKMP QVSVLLSKHA AQLLKDGRLP EAIELQKKAG RYLDAARLMN KLAEREIEKH
SNLLRIKKLY VLAGLLAEQH LKSLAASSAE SPAYNIDRIS IMDTLAPEDS AAIERIWHCA
EAYHFMLLAQ RQLRFGIVHS AVITALRLRE YEDVLNAEDI YSLLALASCA DRSFGTCSKA
FIKLESLDNL PEKSQREYEE LAVNIFSKNE PIDDKVDFIT CYSCTNAVAD CLPACNACGA
RFPPCISSGK PITQPTANIW ICGTCQHCAS PMEITRHRTC PLCHSLILSM TLEV
//
