ID A0A0L0C1M5_LUCCU Unreviewed; 1550 AA.
AC A0A0L0C1M5;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Fanconi anemia group I protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=FF38_06697 {ECO:0000313|EMBL:KNC26166.1};
OS Lucilia cuprina (Green bottle fly) (Australian sheep blowfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Oestroidea;
OC Calliphoridae; Luciliinae; Lucilia.
OX NCBI_TaxID=7375 {ECO:0000313|EMBL:KNC26166.1, ECO:0000313|Proteomes:UP000037069};
RN [1] {ECO:0000313|EMBL:KNC26166.1, ECO:0000313|Proteomes:UP000037069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LS {ECO:0000313|EMBL:KNC26166.1,
RC ECO:0000313|Proteomes:UP000037069};
RC TISSUE=Full body {ECO:0000313|EMBL:KNC26166.1};
RX PubMed=26108605; DOI=10.1038/ncomms8344;
RA Anstead C.A., Korhonen P.K., Young N.D., Hall R.S., Jex A.R., Murali S.C.,
RA Hughes D.S., Lee S.F., Perry T., Stroehlein A.J., Ansell B.R.,
RA Breugelmans B., Hofmann A., Qu J., Dugan S., Lee S.L., Chao H., Dinh H.,
RA Han Y., Doddapaneni H.V., Worley K.C., Muzny D.M., Ioannidis P.,
RA Waterhouse R.M., Zdobnov E.M., James P.J., Bagnall N.H., Kotze A.C.,
RA Gibbs R.A., Richards S., Batterham P., Gasser R.B.;
RT "Lucilia cuprina genome unlocks parasitic fly biology to underpin future
RT interventions.";
RL Nat. Commun. 6:7344-7344(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNC26166.1}.
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DR EMBL; JRES01001007; KNC26166.1; -; Genomic_DNA.
DR STRING; 7375.A0A0L0C1M5; -.
DR EnsemblMetazoa; KNC26166; KNC26166; FF38_06697.
DR OMA; GPFKPLP; -.
DR Proteomes; UP000037069; Unassembled WGS sequence.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR InterPro; IPR026171; FANCI.
DR InterPro; IPR029312; FANCI_HD2.
DR InterPro; IPR029308; FANCI_S1.
DR InterPro; IPR029315; FANCI_S2.
DR InterPro; IPR029313; FANCI_S3.
DR InterPro; IPR029314; FANCI_S4.
DR PANTHER; PTHR21818; BC025462 PROTEIN; 1.
DR PANTHER; PTHR21818:SF0; FANCONI ANEMIA GROUP I PROTEIN; 1.
DR Pfam; PF14680; FANCI_HD2; 1.
DR Pfam; PF14675; FANCI_S1; 1.
DR Pfam; PF14676; FANCI_S2; 1.
DR Pfam; PF14677; FANCI_S3; 1.
DR Pfam; PF14678; FANCI_S4; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000037069}.
FT DOMAIN 82..302
FT /note="FANCI solenoid 1"
FT /evidence="ECO:0000259|Pfam:PF14675"
FT DOMAIN 405..546
FT /note="FANCI solenoid 2"
FT /evidence="ECO:0000259|Pfam:PF14676"
FT DOMAIN 570..786
FT /note="FANCI helical"
FT /evidence="ECO:0000259|Pfam:PF14680"
FT DOMAIN 828..1051
FT /note="FANCI solenoid 3"
FT /evidence="ECO:0000259|Pfam:PF14677"
FT DOMAIN 1085..1316
FT /note="FANCI solenoid 4"
FT /evidence="ECO:0000259|Pfam:PF14678"
FT REGION 1326..1467
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1475..1494
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1511..1550
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1326..1386
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1387..1409
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1410..1467
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1550 AA; 178008 MW; 1E51CF3A40B8DD84 CRC64;
MISVLQIGSR NYKESSQDKT LDGQIIRLGE KHNITQLQNL IEKTTAKELC SLLTSKLGRN
DCTSFWNYLL LGFKPSNYDS KEKRFACVKS FLDGLLKVEL SYKQTYDLIT RLCQDLNTFP
SDQLIQILEH CIDGLRAGDP KCVGWKDLLP ETLNVLASMP HLSVNSITMS GKEYRDMTVK
NLCAMKWPSE VMTPIADMFR ELHLTASETV IVLNKFTGCL QSLAPDALPA LSYQLFSMCS
TASQIIIPIL ALEKYFHRYY YKKLFSDMNS NSTDFDSIDA FSDKELREAE ETILHHLSYC
TQYKINEIQM CIVIRNFLAM PDVLLTPFVL SAILSMTTAN REPDARLSSS VLLPFMRSVI
RNNEEESTLS DYSVWCRDSL QRKRVDLDQL FTVLIDQNKD GKDTVTPGLV NLVFVLLKTK
NNPKLNELAI GFLTKFIRKR FVFGQGIVKR LAEWMIVEQD QNQYSECLTL LSVADTFTVS
ECIKTINYVM DYFVWIPGDQ AMRMMSFILP ILKISPIVRD AFIEVLRKAI SSSEMKTRRM
AVYGFCMILK QLNNSNSQRS QLSASGMCTQ HSISGFSLMS QATLGNRSNP QRHFDMLTLE
IIGVLRNCFH QSLDIKITLY ENLQRAVELN HKLVPHVLQF IDWHFRSFFD APLEEDVDQV
FSIKFDKIVK AKDSLENEIE IHDNLGKLLL FVSHCLVIFE KFETEYDTRE MKRLINVSLE
KVIGKNVKFE DMTGSLTHLK NELILQQLNF IEGLMSYCVL TSKQSNENIK QLLPLFKEHE
HLTEGLKSLS SKKTQKKSKA NTEGENTTIN ITVNGVPVKK IHSQPENIWD LFVIERLMRL
LHEDIVPFAS RNCTAPLRSK VSLVRYVLEV AAAKVEQIRL EPAYKQLAHS KRTLKYLTDI
CKVVYERCIK RLPALWRDFD LKTASLAVEC FRQCLQTANE TYKSKFSSIF IKGFDFHMID
KSKECIQILH DLMDEFMQEE FSMETSANES MLNDSDGRKI PYNLLLSLEI LYDNITFGNR
LTTESYTWLL KFCKTYEIKT KELGLVHKLL FKQRQKTHSG AFFQLIPLHL GQVWSFVRDN
VTEEEDQSTQ LNVTLKSITQ TSAESCLQYL YESLRKQIED VEYFITKANN LSYKCRIVTE
EDRDYCLGCL KSMERSICSQ LVHISNTLKN LTNVCLPLGS SMDGLMKLLM QHFICLKNLA
KHFLTCCAGG VKVSIQGTKF DLLLRVVGKP LPSNIYALIT YIESNILEES TKKKINPQAE
KAKVLRETKF IPKIILCIEN FNKHVIMLAK KTNDRLANLL HYGTVRDFRI KTSDLKAAID
RTLSHSSQIE NDDDTHEDEN AHNSEDGENE EETLLRQIEE ESREIQSTSK VYEQENESEE
NTRSNETDSD ATTNSRSSTP IATTSKAAQK KTQEKAKQTK ETKPKKRKLT DTNEKDEEIK
RPEEKTKKKK VEKEKPSKKS AKIKTTIEID SDNENEITVI TGEEAETLDN ESNRESCTQL
MENLAKINAK TAKKRTLRDS EPQDPDVLCA PPLEPLPKKS KRGRQTRARK
//
