ID A0A0L0C737_LUCCU Unreviewed; 1159 AA.
AC A0A0L0C737;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Ankyrin repeat and FYVE domain-containing protein 1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=FF38_04443 {ECO:0000313|EMBL:KNC28057.1};
OS Lucilia cuprina (Green bottle fly) (Australian sheep blowfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Oestroidea;
OC Calliphoridae; Luciliinae; Lucilia.
OX NCBI_TaxID=7375 {ECO:0000313|EMBL:KNC28057.1, ECO:0000313|Proteomes:UP000037069};
RN [1] {ECO:0000313|EMBL:KNC28057.1, ECO:0000313|Proteomes:UP000037069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LS {ECO:0000313|EMBL:KNC28057.1,
RC ECO:0000313|Proteomes:UP000037069};
RC TISSUE=Full body {ECO:0000313|EMBL:KNC28057.1};
RX PubMed=26108605; DOI=10.1038/ncomms8344;
RA Anstead C.A., Korhonen P.K., Young N.D., Hall R.S., Jex A.R., Murali S.C.,
RA Hughes D.S., Lee S.F., Perry T., Stroehlein A.J., Ansell B.R.,
RA Breugelmans B., Hofmann A., Qu J., Dugan S., Lee S.L., Chao H., Dinh H.,
RA Han Y., Doddapaneni H.V., Worley K.C., Muzny D.M., Ioannidis P.,
RA Waterhouse R.M., Zdobnov E.M., James P.J., Bagnall N.H., Kotze A.C.,
RA Gibbs R.A., Richards S., Batterham P., Gasser R.B.;
RT "Lucilia cuprina genome unlocks parasitic fly biology to underpin future
RT interventions.";
RL Nat. Commun. 6:7344-7344(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNC28057.1}.
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DR EMBL; JRES01000826; KNC28057.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L0C737; -.
DR STRING; 7375.A0A0L0C737; -.
DR EnsemblMetazoa; KNC28057; KNC28057; FF38_04443.
DR EnsemblMetazoa; XM_023445031.2; XP_023300799.1; LOC111683005.
DR OMA; WGLEQVV; -.
DR Proteomes; UP000037069; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd18501; BACK_ANKFY1_Rank5; 1.
DR CDD; cd18303; BTB_POZ_Rank-5; 1.
DR CDD; cd15728; FYVE_ANFY1; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 6.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR049765; ANFY1_BTB_POZ.
DR InterPro; IPR049764; ANFY1_FYVE.
DR InterPro; IPR049763; ANKFY1_BACK.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR24118:SF99; CHARON; 1.
DR PANTHER; PTHR24118; POTE ANKYRIN DOMAIN; 1.
DR Pfam; PF12796; Ank_2; 5.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01363; FYVE; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 20.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 3.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 10.
DR PROSITE; PS50088; ANK_REPEAT; 11.
DR PROSITE; PS50097; BTB; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000037069};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 90..152
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT REPEAT 388..409
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 491..523
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 575..607
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 608..640
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 756..788
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 789..822
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 857..889
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 892..924
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 925..957
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 958..991
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 1031..1063
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 1092..1152
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT COILED 26..53
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1159 AA; 127528 MW; D27280B8C21D3922 CRC64;
MLRECAVAFI QHPHLKKHGS TDAATMQKLE KHLMLLKEEY TKLQRGYADL ERKYSKAIAS
SDNDAGVEFS SFVSRLVLTV ASLYGRTVYS DLTIKMTSKT MPAHKFVLHA RSEEWREEIL
ADVNELDWSD MEEDISMALL RWIYMDVVDL QHDRLALGLL RASHRFHLPG LLGLCERALV
ASVGVRSCVR FYCVAEEVGA ASLLDYCSGL ISTHWDDLTP QDFEHMSGPL LFKMLKSKTK
HPLHAAVRLL REDVVFLCLV ENDGMLSELV NSLSEQGLLP LQMALMAKNL PIAQTLVKNG
SANINAYDSE GSTILIDAVK RGDKFAADFL LEHNCELDLT SRSTADTVLH VLCAYNPKET
DAELFSDMIE IGKRIISMKP NINLQNRQGQ TPLHLAIASN NHDMVDILLG VSNIDINIRT
KDEKCPLELS LTKMTDNDME LANKLIKLGA RPNPLKSETH DNLLQVLAER GLENSAVFLV
DYANLNHINS RGLTALHIAA EKNLPKLTDK LLRAGASPNI QSSVSDLKSA LHVAVESNAA
NVIEIFANFV LGDNGNLPQS KGGQEAPNFN CKNANGDSPL SLSLLLNRTD LVPILIRGGA
DVNARNGQDM TLLHQAILNH DSDTAVFLLQ QGADMNALTG EQESPLQLAI HCHMPHVVDA
LCTRGVALSA PNNKGDAPLW TALELEYDDV AHVLVRHGVD TDCWGPGPDG CQQTLLHRAI
DENKESAAIF LIRSQCDLDS PRQPGANGEG GDEAKDKASP LHLCAQWGLT KVLQTLIDHG
ANVNALDAEN KTPLHVAIEN QHEEIITILL CHPAIDLKIR DKNGNTPFAA ALTIRNHRAA
QRILDRLPNA AEQMDSRGRN FLHLAIMRDD LESVLFLLAI QVDVNSRVHD ANQSTPLHLA
ATSRNEMITR NLILAEARIN ERDAVQKTPL HIAAERGNLP AVSALLQNGS DYDAVDGEGN
NALHIAVRGG HLAIVRELLT ESSINAEAVN HKGRNPLHEL CRTGEDNNAA AICDLFIECM
PKYPLNAPDM DGNTPLLLAF MRGQAPLCKV LVKNGACLGT ENREGISIFN FKLATDQLLH
KLLDQLPQES PWSESDLCQE CNTKFSLTMR KHHCRHCGRV VCSKCSNNDV PILKFGINKP
VRVCGVCFDV LQGVNGNLQ
//
