ID A0A0L0C955_LUCCU Unreviewed; 1025 AA.
AC A0A0L0C955;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Dorsal-ventral patterning protein Sog {ECO:0000313|EMBL:KNC28780.1};
GN ORFNames=FF38_09948 {ECO:0000313|EMBL:KNC28780.1};
OS Lucilia cuprina (Green bottle fly) (Australian sheep blowfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Oestroidea;
OC Calliphoridae; Luciliinae; Lucilia.
OX NCBI_TaxID=7375 {ECO:0000313|EMBL:KNC28780.1, ECO:0000313|Proteomes:UP000037069};
RN [1] {ECO:0000313|EMBL:KNC28780.1, ECO:0000313|Proteomes:UP000037069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LS {ECO:0000313|EMBL:KNC28780.1,
RC ECO:0000313|Proteomes:UP000037069};
RC TISSUE=Full body {ECO:0000313|EMBL:KNC28780.1};
RX PubMed=26108605; DOI=10.1038/ncomms8344;
RA Anstead C.A., Korhonen P.K., Young N.D., Hall R.S., Jex A.R., Murali S.C.,
RA Hughes D.S., Lee S.F., Perry T., Stroehlein A.J., Ansell B.R.,
RA Breugelmans B., Hofmann A., Qu J., Dugan S., Lee S.L., Chao H., Dinh H.,
RA Han Y., Doddapaneni H.V., Worley K.C., Muzny D.M., Ioannidis P.,
RA Waterhouse R.M., Zdobnov E.M., James P.J., Bagnall N.H., Kotze A.C.,
RA Gibbs R.A., Richards S., Batterham P., Gasser R.B.;
RT "Lucilia cuprina genome unlocks parasitic fly biology to underpin future
RT interventions.";
RL Nat. Commun. 6:7344-7344(2015).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the chordin family.
CC {ECO:0000256|ARBA:ARBA00007156, ECO:0000256|PIRNR:PIRNR002496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNC28780.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JRES01000749; KNC28780.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L0C955; -.
DR STRING; 7375.A0A0L0C955; -.
DR EnsemblMetazoa; KNC28780; KNC28780; FF38_09948.
DR OMA; CCKSCPG; -.
DR Proteomes; UP000037069; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0009790; P:embryo development; IEA:UniProt.
DR GO; GO:0007389; P:pattern specification process; IEA:UniProt.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR Gene3D; 6.20.200.20; -; 1.
DR InterPro; IPR016353; Chordin.
DR InterPro; IPR010895; CHRD.
DR InterPro; IPR001007; VWF_dom.
DR PANTHER; PTHR46526; CHORDIN; 1.
DR PANTHER; PTHR46526:SF1; CHORDIN; 1.
DR Pfam; PF07452; CHRD; 2.
DR Pfam; PF00093; VWC; 4.
DR PIRSF; PIRSF002496; Chordin; 1.
DR SMART; SM00754; CHRD; 4.
DR SMART; SM00214; VWC; 4.
DR SUPFAM; SSF57603; FnI-like domain; 4.
DR PROSITE; PS50933; CHRD; 4.
DR PROSITE; PS01208; VWFC_1; 1.
DR PROSITE; PS50184; VWFC_2; 2.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473,
KW ECO:0000256|PIRNR:PIRNR002496};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000037069};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 186..326
FT /note="CHRD"
FT /evidence="ECO:0000259|PROSITE:PS50933"
FT DOMAIN 328..458
FT /note="CHRD"
FT /evidence="ECO:0000259|PROSITE:PS50933"
FT DOMAIN 461..575
FT /note="CHRD"
FT /evidence="ECO:0000259|PROSITE:PS50933"
FT DOMAIN 579..702
FT /note="CHRD"
FT /evidence="ECO:0000259|PROSITE:PS50933"
FT DOMAIN 734..796
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 917..996
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 995..1025
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1008..1025
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1025 AA; 114139 MW; 00BB4DE99FB58DCA CRC64;
MAKITNQTTK SSYSNNSKSS SSTTTTAAAS SSSSLLSPSS SLTTIALKVF IISLICLSQS
GFVEGRKHSP LFVEEAEGNR RNNRPAVSEC QFGKTLRELG STWYADLGPP FGVMYCIKCE
CVAVPKKRRI VARVQCRNIK NECPPALCDD PILLPGKCCK TCPGDKNNET DVALDTPAPI
EEEERNMKHF AALLTGRTSH FLKGEEMKAM YTTHNPHNIV ATGRFMFHKK NLYYSFYTSA
KVNRPRAIQF VDDAGTILEE HQLQLPAGPQ SIYQNVTGKI CGVWRRVPRD YKRLLRDERL
HVVLLWGGNK FQTELALAGK IGKYTALQSE LFSALMEPAP GSKSELMSGS GGTAIVSTSS
GAASSMHLTL VFNGVFTPEE YMDAPVSIRI ESPDRREIVL DEVQKVRKPS SEVNVLEISS
PISIQNLRLM SRGKLLLTIE SKKNPNLRIQ GHIVTRTTCE IFQTLLAPHN VESKAKSSGL
AWVFLNTDGS LAYNIETDQV NARDHPEISL IEDLGKRKTM LEDLTPSFNF NQAIGTVDKL
GPKVVESLYS GDLGVNIAIE HETSLIRGRL VSRPVADARD SAEPILLKRS DNSVSAPNHA
MGMAWLSIDN ECNLHYEITL SGFQSHVQDL QIYLEEKPIE AIGAPVTRKL LEEFNGSYME
GFVLGMPSNE LVKLESSVCY LEIHSKDKKE LLLRGKLKST KVPAHCFPIY TDNNVPNVFL
PGDRNDDVLI TPDTKCFHSG RFYDETEQWR STEDTCQMCA CQRGHATCEP IKCPIIHCKV
NEELVQLEGE CCAMCVPQNL NTNKEVEHSK RGCRLGDQFH LAGATWHPFL PPNGFDTCTT
CTCDALTLEI RCPRMVCPPL QCKEKDAYRP DKKACCKVCP EGKISSRSGG NNNPNVLQDQ
ASSKPNVRST EEILQQGGCK VVNKIYENGQ EWHPVLASHG EQKCIKCRCK DSKVNCDRKR
CSRSTCQQTR VSSKRKLFEK PGSEPVIDEC CSSQCKRPRR HHRRTQQAAE QQQQQQQQPK
KAVSS
//
