ID A0A0L0CAJ8_LUCCU Unreviewed; 546 AA.
AC A0A0L0CAJ8;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Vanin-like protein 1 {ECO:0000313|EMBL:KNC28469.1};
GN ORFNames=FF38_09233 {ECO:0000313|EMBL:KNC28469.1};
OS Lucilia cuprina (Green bottle fly) (Australian sheep blowfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Oestroidea;
OC Calliphoridae; Luciliinae; Lucilia.
OX NCBI_TaxID=7375 {ECO:0000313|EMBL:KNC28469.1, ECO:0000313|Proteomes:UP000037069};
RN [1] {ECO:0000313|EMBL:KNC28469.1, ECO:0000313|Proteomes:UP000037069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LS {ECO:0000313|EMBL:KNC28469.1,
RC ECO:0000313|Proteomes:UP000037069};
RC TISSUE=Full body {ECO:0000313|EMBL:KNC28469.1};
RX PubMed=26108605; DOI=10.1038/ncomms8344;
RA Anstead C.A., Korhonen P.K., Young N.D., Hall R.S., Jex A.R., Murali S.C.,
RA Hughes D.S., Lee S.F., Perry T., Stroehlein A.J., Ansell B.R.,
RA Breugelmans B., Hofmann A., Qu J., Dugan S., Lee S.L., Chao H., Dinh H.,
RA Han Y., Doddapaneni H.V., Worley K.C., Muzny D.M., Ioannidis P.,
RA Waterhouse R.M., Zdobnov E.M., James P.J., Bagnall N.H., Kotze A.C.,
RA Gibbs R.A., Richards S., Batterham P., Gasser R.B.;
RT "Lucilia cuprina genome unlocks parasitic fly biology to underpin future
RT interventions.";
RL Nat. Commun. 6:7344-7344(2015).
CC -!- SIMILARITY: Belongs to the carbon-nitrogen hydrolase superfamily.
CC BTD/VNN family. {ECO:0000256|ARBA:ARBA00008225}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNC28469.1}.
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DR EMBL; JRES01000767; KNC28469.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L0CAJ8; -.
DR STRING; 7375.A0A0L0CAJ8; -.
DR EnsemblMetazoa; KNC28469; KNC28469; FF38_09233.
DR OMA; HLWRHEY; -.
DR Proteomes; UP000037069; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR Gene3D; 3.60.110.10; Carbon-nitrogen hydrolase; 1.
DR InterPro; IPR040154; Biotinidase/VNN.
DR InterPro; IPR003010; C-N_Hydrolase.
DR InterPro; IPR036526; C-N_Hydrolase_sf.
DR InterPro; IPR043957; Vanin_C.
DR PANTHER; PTHR10609:SF14; BIOTINIDASE; 1.
DR PANTHER; PTHR10609; BIOTINIDASE-RELATED; 1.
DR Pfam; PF00795; CN_hydrolase; 1.
DR Pfam; PF19018; Vanin_C; 1.
DR SUPFAM; SSF56317; Carbon-nitrogen hydrolase; 1.
DR PROSITE; PS50263; CN_HYDROLASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000037069};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..546
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5005536059"
FT TRANSMEM 525..543
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 29..292
FT /note="CN hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS50263"
SQ SEQUENCE 546 AA; 62241 MW; 9B5B1DA08D06863B CRC64;
MGFKNAILFL VLAILQLTEQ LSLPSDPTYN AGVVEFIPAM NGQGKVLVKD NLKRMKNIIE
SEQTKDLDIL VFPEFVLNNL DMMTFVPDPK DNIVPCELPN YDWFLSELSC VVRSRKLYVV
INIVEKFECL ASEEHCDDDG LKKYNTNIVF DRQGRVISRY RKTHLYRYEW YKESVLPQAE
LATFTTDFGV TFGHFICFDM LFYEPAMVLI RQLNITDIVY PTYWFSELPF LTAVQLQEGW
AFANNVNLLA ADGSYPAGQN TGSGIFAGRL GRLTAVINEV PTTQLLTAKV PKHQNLSNYQ
LPPVVKPLFE PKLESNRYTK LDLLRDYNVD IFNTSLLEES FTQVNEMLCH HNFCCSFNVQ
RVKIADSIKH SSYRYRLAAY QGSQTTFQRI DSSNQSVCAL IACTGSELYT CGHIFPESVL
VGNKYYFSTI NITGNFIKSN RRLIMPSTVN SVMLPLTVDS FEWKELDSNS STNIQMNLLG
PQQDLLTFGI WANYYSTVKN THNLYTVTKN APKPVHNSAF PLNTIFNNIL VLGLLMFVAN
NLFKTI
//
