ID A0A0L0CC09_LUCCU Unreviewed; 1043 AA.
AC A0A0L0CC09;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|SMART:SM00913};
GN ORFNames=FF38_13790 {ECO:0000313|EMBL:KNC28979.1};
OS Lucilia cuprina (Green bottle fly) (Australian sheep blowfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Oestroidea;
OC Calliphoridae; Luciliinae; Lucilia.
OX NCBI_TaxID=7375 {ECO:0000313|EMBL:KNC28979.1, ECO:0000313|Proteomes:UP000037069};
RN [1] {ECO:0000313|EMBL:KNC28979.1, ECO:0000313|Proteomes:UP000037069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LS {ECO:0000313|EMBL:KNC28979.1,
RC ECO:0000313|Proteomes:UP000037069};
RC TISSUE=Full body {ECO:0000313|EMBL:KNC28979.1};
RX PubMed=26108605; DOI=10.1038/ncomms8344;
RA Anstead C.A., Korhonen P.K., Young N.D., Hall R.S., Jex A.R., Murali S.C.,
RA Hughes D.S., Lee S.F., Perry T., Stroehlein A.J., Ansell B.R.,
RA Breugelmans B., Hofmann A., Qu J., Dugan S., Lee S.L., Chao H., Dinh H.,
RA Han Y., Doddapaneni H.V., Worley K.C., Muzny D.M., Ioannidis P.,
RA Waterhouse R.M., Zdobnov E.M., James P.J., Bagnall N.H., Kotze A.C.,
RA Gibbs R.A., Richards S., Batterham P., Gasser R.B.;
RT "Lucilia cuprina genome unlocks parasitic fly biology to underpin future
RT interventions.";
RL Nat. Commun. 6:7344-7344(2015).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNC28979.1}.
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DR EMBL; JRES01000720; KNC28979.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L0CC09; -.
DR STRING; 7375.A0A0L0CC09; -.
DR EnsemblMetazoa; KNC28979; KNC28979; FF38_13790.
DR EnsemblMetazoa; XM_023435581.2; XP_023291349.1; LOC111674899.
DR OMA; KITRFNH; -.
DR OrthoDB; 169519at2759; -.
DR Proteomes; UP000037069; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006611; P:protein export from nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR040016; XPO6.
DR PANTHER; PTHR21452; EXPORTIN-6; 1.
DR PANTHER; PTHR21452:SF4; EXPORTIN-6; 1.
DR Pfam; PF03810; IBN_N; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000037069};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 28..98
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|SMART:SM00913"
SQ SEQUENCE 1043 AA; 119094 MW; FEC4472AA292173B CRC64;
MSSPLALMDS LLREFYSTAT PNNRKREIET ELISFKSQAE SWKTCLSVVG NGSIFEQNQF
LWFFCTSTLE HAITRRWMQL GSADRAHMRE ALWTAYVNLP PRSQKRQRDT YAQLIALMGK
REFPDEDPNY IMHCLTLVKS NFVLGICLLR TTSEEVVSNR EDVSTDRKQY FHSCTSMCMP
EVMDLLTKYL LIAVCHINGK DIHSISNTLM DYSLVTSLPN DNQLSSSVLE LLTCIQHLVS
WVRTDLISEY FLMSILDISQ WRSSHQDLSL AGLNILNELL YLQKSLPYNV TLMSGINVLL
DQHNTSKQQS EMYIDKFREL LRLYAAKYWL KMLQESTVLD GFLKSLYCCT VFQNGAYDFT
EKLEIWTPII KGLTMHDKLN RYNDVIHQLV SEIMHRTQFE YNKTELELLD NELMEDNTQT
EWQQYLTQCI ECIALIAESR PNAVFAQVFS HWSRPHVYLQ SIENDINSGK SFELSRKLKS
QNFAEHLRDF STVCQAVVRI APLLDTNTTA EASSEVNCHL NILAENLLTT LKFFTSNKLH
TIDVDASTFQ TDFDYLYAQV LMAIRSILPL CQSLKSDQML LQLFDSLGSI FQPNTIMGSS
PLIYMAASQL LLCISSVIRP KCLLEIPTIV NLMQSGPRLT HLPRQVIANI YISLISYLVL
PWKNVDEQQQ DYSRRCLILR EYIECLAQGF LELDLNSLNA ATAEAKVSSI SLSLLVTFSL
VIEFFKDSPN TTKDMLSSTF KPIITKALMI YNSFGHNSNA ISITVAEFSL SVLRTLQSQL
GSQFIKEMIT LFITVNVREQ LTLSRVVVIE KILQMFQLIV QQPGNASLAM LPSILDFTFE
HIMPLLQVEN SVADTTDLTS VVYSLFDSIL TCKWQYFYKS HVQPNGVLQQ QNGNNSSPTI
NPTDNLHPEH FMAIMNAYGQ IVVTGNDPNI VRTVLISMQN VHEKWRLYQR PLFKENLLAS
FQRALINVLL SGEGALHFDL LTNALFAMSQ VDALKMRESF ANAGLPINMK LIDEICLTTD
IPTFSQKLTQ LIQDAHCVHL TQT
//
