ID A0A0L0CQG1_LUCCU Unreviewed; 473 AA.
AC A0A0L0CQG1;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Protein deadpan {ECO:0000313|EMBL:KNC33674.1};
GN ORFNames=FF38_08755 {ECO:0000313|EMBL:KNC33674.1};
OS Lucilia cuprina (Green bottle fly) (Australian sheep blowfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Oestroidea;
OC Calliphoridae; Luciliinae; Lucilia.
OX NCBI_TaxID=7375 {ECO:0000313|EMBL:KNC33674.1, ECO:0000313|Proteomes:UP000037069};
RN [1] {ECO:0000313|EMBL:KNC33674.1, ECO:0000313|Proteomes:UP000037069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LS {ECO:0000313|EMBL:KNC33674.1,
RC ECO:0000313|Proteomes:UP000037069};
RC TISSUE=Full body {ECO:0000313|EMBL:KNC33674.1};
RX PubMed=26108605; DOI=10.1038/ncomms8344;
RA Anstead C.A., Korhonen P.K., Young N.D., Hall R.S., Jex A.R., Murali S.C.,
RA Hughes D.S., Lee S.F., Perry T., Stroehlein A.J., Ansell B.R.,
RA Breugelmans B., Hofmann A., Qu J., Dugan S., Lee S.L., Chao H., Dinh H.,
RA Han Y., Doddapaneni H.V., Worley K.C., Muzny D.M., Ioannidis P.,
RA Waterhouse R.M., Zdobnov E.M., James P.J., Bagnall N.H., Kotze A.C.,
RA Gibbs R.A., Richards S., Batterham P., Gasser R.B.;
RT "Lucilia cuprina genome unlocks parasitic fly biology to underpin future
RT interventions.";
RL Nat. Commun. 6:7344-7344(2015).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNC33674.1}.
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DR EMBL; JRES01000171; KNC33674.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L0CQG1; -.
DR STRING; 7375.A0A0L0CQG1; -.
DR EnsemblMetazoa; KNC33674; KNC33674; FF38_08755.
DR OMA; YVSQMDG; -.
DR Proteomes; UP000037069; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd18913; bHLH-O_hairy_like; 1.
DR Gene3D; 6.10.250.980; -; 1.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR003650; Orange_dom.
DR PANTHER; PTHR10985; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED; 1.
DR PANTHER; PTHR10985:SF137; PROTEIN DEADPAN-RELATED; 1.
DR Pfam; PF07527; Hairy_orange; 1.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SMART; SM00511; ORANGE; 1.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR SUPFAM; SSF158457; Orange domain-like; 1.
DR PROSITE; PS50888; BHLH; 1.
DR PROSITE; PS51054; ORANGE; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000037069}.
FT DOMAIN 56..113
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT DOMAIN 132..165
FT /note="Orange"
FT /evidence="ECO:0000259|PROSITE:PS51054"
FT REGION 329..397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 415..473
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 415..443
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 444..473
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 473 AA; 52180 MW; 3E4838BD499A222F CRC64;
MDYKNEFQSD DDFDCSNSYN NDNFQQQTAA QNAAQNQFNT SQGRLNNNAG LSKAELRKTN
KPIMEKRRRA RINHCLNELK SLILEAMKKD PARHTKLEKA DILEMTVKHL QSVQRQQLNM
ALQTDPTVIH KFKTGFMECA DEVNRYVSQL DGVEDGVRQR LNSHLNNCAT SLEQIGSMTN
FSNGYRSGAS SNFFANTNSM PLPTTGSLFP ALPQDLNNNP AGGIQMGGVQ LIPSRLPSGE
FALIVPNTAN NTTAAASLIN SNSNSGFPSW PGNNTTAASN NSTPINDFAA NFKRLSAFSK
PQNTLITPLK VPVGNSYPQT NLTHTNYQLQ TTQQQQQQQQ AFHTTTTTSP PLSPISSVSS
HNEDSNMHTS SDFTNSRSVS PRQDKHNSFS GVFASPPSSA ENSFVLSAAH LQQQQVTSTS
SNSDLNTSSS SSLKRSFSET ADSSICSEDE HTSKKYQREQ QDAEDQDSMW RPW
//
