ID A0A0L0CQV6_LUCCU Unreviewed; 212 AA.
AC A0A0L0CQV6;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Homologous-pairing protein 2 homolog {ECO:0000256|ARBA:ARBA00016093};
GN ORFNames=FF38_09353 {ECO:0000313|EMBL:KNC34572.1};
OS Lucilia cuprina (Green bottle fly) (Australian sheep blowfly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Oestroidea;
OC Calliphoridae; Luciliinae; Lucilia.
OX NCBI_TaxID=7375 {ECO:0000313|EMBL:KNC34572.1, ECO:0000313|Proteomes:UP000037069};
RN [1] {ECO:0000313|EMBL:KNC34572.1, ECO:0000313|Proteomes:UP000037069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LS {ECO:0000313|EMBL:KNC34572.1,
RC ECO:0000313|Proteomes:UP000037069};
RC TISSUE=Full body {ECO:0000313|EMBL:KNC34572.1};
RX PubMed=26108605; DOI=10.1038/ncomms8344;
RA Anstead C.A., Korhonen P.K., Young N.D., Hall R.S., Jex A.R., Murali S.C.,
RA Hughes D.S., Lee S.F., Perry T., Stroehlein A.J., Ansell B.R.,
RA Breugelmans B., Hofmann A., Qu J., Dugan S., Lee S.L., Chao H., Dinh H.,
RA Han Y., Doddapaneni H.V., Worley K.C., Muzny D.M., Ioannidis P.,
RA Waterhouse R.M., Zdobnov E.M., James P.J., Bagnall N.H., Kotze A.C.,
RA Gibbs R.A., Richards S., Batterham P., Gasser R.B.;
RT "Lucilia cuprina genome unlocks parasitic fly biology to underpin future
RT interventions.";
RL Nat. Commun. 6:7344-7344(2015).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the HOP2 family.
CC {ECO:0000256|ARBA:ARBA00007922}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNC34572.1}.
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DR EMBL; JRES01000049; KNC34572.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L0CQV6; -.
DR STRING; 7375.A0A0L0CQV6; -.
DR EnsemblMetazoa; KNC34572; KNC34572; FF38_09353.
DR OMA; QKYHREW; -.
DR Proteomes; UP000037069; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR010776; Hop2_WH_dom.
DR InterPro; IPR040661; LZ3wCH.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR15938:SF0; HOMOLOGOUS-PAIRING PROTEIN 2 HOMOLOG; 1.
DR PANTHER; PTHR15938; TBP-1 INTERACTING PROTEIN; 1.
DR Pfam; PF18517; LZ3wCH; 1.
DR Pfam; PF07106; TBPIP; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000037069}.
FT DOMAIN 6..66
FT /note="Homologous-pairing protein 2 winged helix"
FT /evidence="ECO:0000259|Pfam:PF07106"
FT DOMAIN 152..205
FT /note="Leucine zipper with capping helix"
FT /evidence="ECO:0000259|Pfam:PF18517"
FT COILED 64..142
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 212 AA; 24530 MW; 5A7C0579B041F2F1 CRC64;
MSKSEVLKTV QQFMLQENRP YAVHEVLEKC GKDLGKAAIQ KALDSLVSKE ILLAKSYGKH
KIYFAKQNVN NQELKKQMQT LKQKLSQAQN TLKNKESELN DLEMKLKPLN KVKSLATLEE
ERDKLLNDIR HTNEKLKSFQ AQEMQNKLNS QDVKKILTKY ENVSLAYRKR KRMCNDMLEA
IMEGYPKTKK ALIADIGLET DEEVGFNVQL KL
//
