ID A0A0L0CTK0_PLAFA Unreviewed; 2184 AA.
AC A0A0L0CTK0;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Dynein beta chain {ECO:0000313|EMBL:KNC35775.1};
GN ORFNames=PFLG_00990 {ECO:0000313|EMBL:KNC35775.1};
OS Plasmodium falciparum RAJ116.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=580058 {ECO:0000313|EMBL:KNC35775.1, ECO:0000313|Proteomes:UP000054566};
RN [1] {ECO:0000313|Proteomes:UP000054566}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RAJ116 {ECO:0000313|Proteomes:UP000054566};
RG The Broad Institute Genome Sequencing Platform;
RA Volkman S.K., Neafsey D.E., Dash A.P., Chitnis C.E., Hartl D.L.,
RA Young S.K., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D.,
RA Chapman S.B., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E.R., Heiman D.I., Howarth C., Jen D.,
RA Larson L., Mehta T., Neiman D., Park D., Pearson M., Roberts A., Saif S.,
RA Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT "Annotation of Plasmodium falciparum RAJ116.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000054566}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RAJ116 {ECO:0000313|Proteomes:UP000054566};
RG The Broad Institute Genome Sequencing Platform;
RA Volkman S.K., Neafsey D.E., Dash A.P., Chitnis C.E., Hartl D.L.,
RA Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Godfrey P., Alvarado L.,
RA Berlin A., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C.,
RA Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A.,
RA Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T.,
RA White J., Yandava C., Wirth D.F., Nusbaum C., Birren B.;
RT "The genome sequence of Plasmodium falciparum RAJ116.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GG663917; KNC35775.1; -; Genomic_DNA.
DR EnsemblProtists; KNC35775; KNC35775; PFLG_00990.
DR OrthoDB; 211054at2759; -.
DR Proteomes; UP000054566; Unassembled WGS sequence.
DR GO; GO:0030286; C:dynein complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041589; DNAH3_AAA_lid_1.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10676:SF183; DYNEIN AXONEMAL HEAVY CHAIN 2; 1.
DR PANTHER; PTHR10676; DYNEIN HEAVY CHAIN FAMILY PROTEIN; 1.
DR Pfam; PF12774; AAA_6; 2.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF17857; AAA_lid_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054566}.
FT DOMAIN 332..448
FT /note="Dynein heavy chain hydrolytic ATP-binding dynein
FT motor region"
FT /evidence="ECO:0000259|Pfam:PF12774"
FT DOMAIN 602..815
FT /note="Dynein heavy chain hydrolytic ATP-binding dynein
FT motor region"
FT /evidence="ECO:0000259|Pfam:PF12774"
FT DOMAIN 1611..1688
FT /note="Dynein heavy chain 3 AAA+ lid"
FT /evidence="ECO:0000259|Pfam:PF17857"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1927..1946
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1983..2011
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1983..1998
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2184 AA; 258971 MW; 76AB89526DCB95A3 CRC64;
MQLKVQQKNH YIEGGGSKNE IDNDVTNMKN TNQFSNIHTN LNEKKKNANN IIKNKNKNII
NNNKKSDING KVKIENINKN KQDNLVKEEV DNNNYNIYEN NNKKGVEVKI QLNNKIPNKS
DIPFNEDIHY NIKKNSYIDC YNDDKKGEKL FNDEKGNIPN RFSGEDNNIE IDDQYDNPLA
EEKKNDENKQ LNSLYNIDED INEDININNN ENENENNNNT NEHNINKIYK EKEEKNHNIP
KEVIINKEKM VTNNILLKKS KKKKKNNTIT TNLNDNNMDN LISKDTSKAE YSNDPDMINK
NNKQLKYLKT INLMLNKSMT LYLNYFNNRR KYSYEYQGNT TRLVITPLTE KCFYSCLISL
DNFYVNAIQG DTGVGKSETI KDFSKLFGSN IISINCNNNN TAKYIGNILS GILQSGFWCC
FDEFSRIDES VIVIIVEQFR CIKHILQSLE FNKSNKQQGY LNYEYISSYQ KGYNWKVKTD
DDGYDDDKSN SSFETFCNEY DPDNNTNENN DMLLMVDSHS NKKIKSNQKI YTNELNNITN
ENYTDDFQIM NKRNDVVKLK EYSSKTNNNM NTFDIFSNNN KKNNKNLVTN NTVNSNNTRL
GSNNNAYFEG QYINVKNSCS IFLTLCKNNN KGVYSLENYN NVIQVFCFKP PNFYLICQFS
LTSIGFKNSK KLSKKINTCY SLLYEFLSKD KQYIIDLREI KKFLNLVSED FIKNNKTKCE
EEIIYDALIE VNESKLLKDD LYIFNNFLKE LFPFIKIKNE KNKQNDSSIK IIEEIMKNMG
YTRNEFYINK ILNLYKIKKT NKAIILVGKS CSGKTSIINI FKHYCEIIKN NTMKDKNDLG
QMTYDIDLEY KNKCNLSNEY DYDNENNENN KLYMNNDESI YSNQINISDL SQSTTTPNNN
ININNINLNN NSKGTYESYN LLCPYNLFYN KFKNQGNTNN MTNNMSTKKS SKLSNTYSMQ
IKNSAGTLLD MSYKYKRSTE MNDFTIDITV FNPMSTDVQK LYGFYNFEKE LYEDGILALI
LKRMVENINE NEKCKELFDK LIKSIDNTFP YLHTVFDYII SKNNFNWVLW DELITTNHNF
LPNIKEKFFF SYDNYNIGKN DSNSFKYMNV NQLGDTANQE TDFNKFFLSS NLHFSKNFNK
YTINYNNLFS DNNNVNNNEN TLNIYQTYHQ SFMSSNMNNM NEMNMLDNYH MFSNYSEDNI
HSNNNNYFDS SMFNNNSKNL SNPYFSGNTF SHNEFSDNTF SYRYNMNKTK NRFGNMHNND
NYMKSSDNYV NYDDNIKNIA VNNNMDYNND HNNDHNNIHD DHFNIVNDNY IESYNNLSMK
DNIYSKKDEY NENYMEKTKE KYFHQNFKDN IFIENVESLR KKNMISILMY NKKNILLIGN
KYSGKTFFMK YNILPYIKED ISSYYTFISK LYNSSKLEKI IEMNVEKKCR NVYKPIGNKK
CLYIILDDLN NIQKSNNSYI EDYNNNNNMI QNNLFFNFDM NHKNDISTNI YDNNNYNNNK
MRYLNNCSVL EFINQFIDYN IYFNKDSDSV KNVENLVFFL IYGNNKKYTS TFNRKIINRM
YIIHLNEMDE TNIKNTFHAF LRHKFTNFHE VIKNLSEPLS ASTVRFVFES AKNFKPNLNC
YHYFFHLKHI FKIIKGIFLS EAPIYEEKES VLRLWVNECC RSLGDQLILQ TERKRFKTIL
KNILRKKFYI MYNYLFPKRK TFYFCSYNFH DTKNEKPYFF YQPISNENVL IEFFKNVISS
INTFVVCNYD QKKKEYFRNE KGDSNINVNN EKKKTNIHLN KNEEMKKYNE NSTYTILNTK
VDSKAININK EDEMVYTNIN RADNIKEMMN VSLEKGQIKI SKEIEKLVNK NDNDFNNMNN
PINFILFKDV MLNICKFSRI FLFENEHFIS IGDSSQGKFT CCLIACYIYQ IKIDVIKNFY
YNKMNMENID DDDDNNNNNN NAKSDMNKED MNYILESNND KNDTNVVNKV VDEEENKEIM
EIQGTYEKDE DNKDQQSDIN NDTNRTNNID TFSNTSENNI LINMNNSIHH IDYIQNDNMK
CNKGISDKEE QPNKLNTNLL NNKNLSVIEK LKCNYFIKKF KEAIFNCYKN EKRCVLYYLD
DKMNYDILEF LHILYNNDNL INIFNSEEIA FLKNILLQNE INLKGFDTLD EMIEELIRRN
YHYILFTSLK VKCLKKYPMN IILY
//
