ID   A0A0L0D1Q7_THETB        Unreviewed;       799 AA.
AC   A0A0L0D1Q7;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=Ubiquitin carboxyl-terminal hydrolase 2 {ECO:0000313|EMBL:KNC46136.1};
GN   ORFNames=AMSG_00254 {ECO:0000313|EMBL:KNC46136.1};
OS   Thecamonas trahens ATCC 50062.
OC   Eukaryota; Apusozoa; Apusomonadida; Apusomonadidae; Thecamonas.
OX   NCBI_TaxID=461836 {ECO:0000313|EMBL:KNC46136.1, ECO:0000313|Proteomes:UP000054408};
RN   [1] {ECO:0000313|EMBL:KNC46136.1, ECO:0000313|Proteomes:UP000054408}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 50062 {ECO:0000313|EMBL:KNC46136.1,
RC   ECO:0000313|Proteomes:UP000054408};
RG   The Broad Institute Genome Sequencing Platform;
RA   Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA   Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA   Borenstein D., Chapman S., Chen Z., Freedman E., Gellesch M., Goldberg J.,
RA   Griggs A., Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D.,
RA   Larson L., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA   Burger G., Gray M.W., Holland P.W.H., King N., Lang F.B.F., Roger A.J.,
RA   Ruiz-Trillo I., Lander E., Nusbaum C.;
RT   "The Genome Sequence of Thecamonas trahens ATCC 50062.";
RL   Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GL349433; KNC46136.1; -; Genomic_DNA.
DR   RefSeq; XP_013763113.1; XM_013907659.1.
DR   AlphaFoldDB; A0A0L0D1Q7; -.
DR   STRING; 461836.A0A0L0D1Q7; -.
DR   EnsemblProtists; KNC46136; KNC46136; AMSG_00254.
DR   GeneID; 25560070; -.
DR   eggNOG; KOG1868; Eukaryota.
DR   OrthoDB; 5474185at2759; -.
DR   Proteomes; UP000054408; Unassembled WGS sequence.
DR   GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:InterPro.
DR   Gene3D; 3.90.70.10; Cysteine proteinases; 2.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR001394; Peptidase_C19_UCH.
DR   InterPro; IPR018200; USP_CS.
DR   InterPro; IPR028889; USP_dom.
DR   PANTHER; PTHR21646; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR   Pfam; PF00443; UCH; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
DR   PROSITE; PS00973; USP_2; 1.
DR   PROSITE; PS50235; USP_3; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:KNC46136.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054408}.
FT   DOMAIN          291..740
FT                   /note="USP"
FT                   /evidence="ECO:0000259|PROSITE:PS50235"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          99..176
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          190..224
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          401..454
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          774..799
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        99..113
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        117..140
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        401..415
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        416..435
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   799 AA;  86505 MW;  262CED98433D665F CRC64;
     MAASRSTFEH RPSPLSAEKP RMSEDILPIR AWLLSTGTPA ATIEAIDNLS WETLGAGNAN
     RVLDRFRSWF GSKGNGMYLE YTNLLENLAP DAVARVSTTD NLHSPNASSS GGDDVPVTPP
     RRKRPPRDWD AWRDAGSDDE SAEMAGSASG WPAPDSTTPL KLRLSPPPPV EPNPSLSRLA
     IANSATARAA AREDATAAAE RFSSTHSLRH RRKRHRPPPK LDLSSVAAPG TDIAWTVCAS
     VECTKDANPD DVFHPGFCSF FCMSRAEDAQ LQAAMFESTR GTVAITPRGV RGLENMGNTC
     YLNTGLELLF NLPFLVSPRD GLFAPSDASP RGLREQVAAL ARTRAEQAAA FRDAGDWERA
     LASFTLAAAL DSNREVLVRS DLELCTAMVA SVGSLTTVRY VPTEATTTPE TEASSEASAK
     PEHEHESEPE PEPGTSPERQ RSPTADPREL RPVRVSLSPE MERIATVLEA GKVLMAFRKL
     LADVWMPDAA TPLEPKAVHD ALPPTRFGKW AQEDVHDLLS FLLDALETAT STADDVFELA
     SAQENDATLD AVRDAHPSLV ADATLGVLYH SWQCTTCGES RTVREPFSWL TLPIPDATDD
     DPDDRRRRGI WSTIVVDNVM CAGCDGPRPC ERTTTIESLP TVLFVALSRF AGSCALRKKT
     DTVRYPLASL VLDGASDGSY MLTGVGLHRG PFGGGHYTSY VRSLADTYWY NLNDEYASLL
     AEPEVDVISP HAYVLVYTRA DKWDAARTAV AGTVLDCHNL TTSIAGAESI RPVRPDLTTT
     PASPDAFTRP GTAISDAEL
//