ID A0A0L0D216_THETB Unreviewed; 471 AA.
AC A0A0L0D216;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Kinase-like protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=AMSG_11730 {ECO:0000313|EMBL:KNC46246.1};
OS Thecamonas trahens ATCC 50062.
OC Eukaryota; Apusozoa; Apusomonadida; Apusomonadidae; Thecamonas.
OX NCBI_TaxID=461836 {ECO:0000313|EMBL:KNC46246.1, ECO:0000313|Proteomes:UP000054408};
RN [1] {ECO:0000313|EMBL:KNC46246.1, ECO:0000313|Proteomes:UP000054408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50062 {ECO:0000313|EMBL:KNC46246.1,
RC ECO:0000313|Proteomes:UP000054408};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA Borenstein D., Chapman S., Chen Z., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D.,
RA Larson L., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA Burger G., Gray M.W., Holland P.W.H., King N., Lang F.B.F., Roger A.J.,
RA Ruiz-Trillo I., Lander E., Nusbaum C.;
RT "The Genome Sequence of Thecamonas trahens ATCC 50062.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL349442; KNC46246.1; -; Genomic_DNA.
DR RefSeq; XP_013760753.1; XM_013905299.1.
DR AlphaFoldDB; A0A0L0D216; -.
DR STRING; 461836.A0A0L0D216; -.
DR EnsemblProtists; KNC46246; KNC46246; AMSG_11730.
DR GeneID; 25569645; -.
DR eggNOG; KOG0032; Eukaryota.
DR eggNOG; KOG1474; Eukaryota.
DR OrthoDB; 152619at2759; -.
DR Proteomes; UP000054408; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd04369; Bromodomain; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR24349:SF243; CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE IV; 1.
DR PANTHER; PTHR24349; SERINE/THREONINE-PROTEIN KINASE; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF00069; Pkinase; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PIRSR:PIRSR630616-2};
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR630616-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000054408}.
FT DOMAIN 34..319
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 375..447
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT ACT_SITE 162
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR630616-1"
FT BINDING 63
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR630616-2"
FT BINDING 198
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR630616-2"
FT CROSSLNK 164
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2)"
FT /evidence="ECO:0000256|PIRSR:PIRSR630616-3"
SQ SEQUENCE 471 AA; 51960 MW; 5824B78D2196BA2F CRC64;
MLRAPASPDV EARMKKALYA RYPPGRSFAE QYALESRVNA SARQNRAIYA AIRLKDGVQV
AVKVISKTYP RQLARDEIDA LRREALIQIA VSRHPHCVTL LDYFETKKKI YIVMEYMDGG
DLLDFLGSRP GSRFTEGDAR ALLGTLAGTL AWLHGHSICH RDLKPSNVLL VSVPEGTDLV
PGSLPGGCLE GYVVKISDFG LSTFLTSAMT TPVGTRSFAA PELLNWSAAA SPVAGSSPPT
SLGRRQSSTA YSEAVDIWSF GIIMYIVLIG TMPPTPLAFP PFATAPVSNE AKALISALIH
PDPAERPSAL EYTEPEPVFR PYAVMKIELN GSRRELTREE YGELEEELDS IAEWTLPPQD
QGWHDALMGI VQELKKHPKA DLFSVPVDPQ AHGVPDYFTV IHHPMDLSTV ETNLASGIYP
EPEMVIDDIR RVFHNCFIYN GKNNWVTDSA RTISKLAEDA FIKLNALGMR Q
//
