ID A0A0L0D3I0_THETB Unreviewed; 1461 AA.
AC A0A0L0D3I0;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Voltage-gated ion channel superfamily protein {ECO:0000313|EMBL:KNC46760.1};
GN ORFNames=AMSG_03189 {ECO:0000313|EMBL:KNC46760.1};
OS Thecamonas trahens ATCC 50062.
OC Eukaryota; Apusozoa; Apusomonadida; Apusomonadidae; Thecamonas.
OX NCBI_TaxID=461836 {ECO:0000313|EMBL:KNC46760.1, ECO:0000313|Proteomes:UP000054408};
RN [1] {ECO:0000313|EMBL:KNC46760.1, ECO:0000313|Proteomes:UP000054408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50062 {ECO:0000313|EMBL:KNC46760.1,
RC ECO:0000313|Proteomes:UP000054408};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA Borenstein D., Chapman S., Chen Z., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D.,
RA Larson L., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA Burger G., Gray M.W., Holland P.W.H., King N., Lang F.B.F., Roger A.J.,
RA Ruiz-Trillo I., Lander E., Nusbaum C.;
RT "The Genome Sequence of Thecamonas trahens ATCC 50062.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL349444; KNC46760.1; -; Genomic_DNA.
DR RefSeq; XP_013760040.1; XM_013904586.1.
DR STRING; 461836.A0A0L0D3I0; -.
DR EnsemblProtists; KNC46760; KNC46760; AMSG_03189.
DR GeneID; 25562810; -.
DR eggNOG; KOG2301; Eukaryota.
DR OMA; CARIAFH; -.
DR OrthoDB; 1110761at2759; -.
DR Proteomes; UP000054408; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005261; F:monoatomic cation channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 4.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 4.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR043203; VGCC_Ca_Na.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR10037:SF62; SODIUM CHANNEL PROTEIN 60E; 1.
DR PANTHER; PTHR10037; VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM; 1.
DR Pfam; PF00520; Ion_trans; 4.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 4.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054408};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 127..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 440..459
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 474..493
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 505..530
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 565..582
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 603..623
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 635..661
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 836..854
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 866..887
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 919..941
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1024..1047
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1108..1126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1138..1156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1176..1201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1229..1252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1302..1330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 18..285
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 441..665
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 807..1054
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 1108..1326
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT REGION 312..358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 694..734
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..346
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1461 AA; 161149 MW; 32C2E4BB8C9EF926 CRC64;
MKPSNWLRYT CIRIVDNLWF ERAVLSVIVA NVVILILESR FSESTFEALE IGFSVVYTIE
MMLKITASGV WRHKTAYFRD GWNWLDFVVV VVGWLTLVPG VKNATAIRGL RVLRTLRTLR
HVRGLRVLIE TFLSAVPTFA RVLVLIGFVM VFFAIYGTNL WSGNLRQHCV GFGIVDEDVR
CSRDPSHGLQ CPTVSAFNPV SCVKLGEERN PDRGFTSFDH FGFASLAAFR VFSGDEWAEL
LFFVMDSWSA WAVVLFLPFV LFSSLFAINF MLAALFDHYV DIEAEARAQD EALESAIAHA
RTLAAMIRTR HHHGAHRGGS GSDDDDNDYE SGYGEYEYDS EPDYSEEQEA SSSASSTSSY
MTLYSEPSQA EAKAEVVRRY KPAHGVGEAP RWWEHPIGAF QFRHREAFNF FSVPQHKLKA
EYLSNKPGFV SALRRMTDSV AFSVVIGALV LANVVVMALE HASMSESNRD KLDLANAIFI
GAFILEFFVK LAAMGVKGYL RDRFNIFDAL VVLASVIELL FASTTSISVF RALRVARIFR
LARTARWMTY VRTTLHCAYK SVPNTLFLVV LTSLFALVFA LIGKQLFQDE MRFDETDVPR
TNFDSVFSSL VSVFVLMSGK GFATTLYDTM EVEPWYGAPF CIVVFVFGKL LVVNLFAVVI
LSNWDPVGAQ AEAEADARDT STASESYSYV ADSSELDSYS EEQEEASRKR GGGKKKRRKS
AKRESSSSSS LSSLSSLSEY GTRTAALGYS SDEVGGGSGV CGAAGRWLYE LVTVPRSDGH
VGVPVHLAKT KPEGVASGAW LVASQGYEMV VDVLIVAACV YLFWDEPGSE GDVLRVLDIV
VFVLFALEAA VRVATYRTAL LRDASAWLDV VALAGCGLGL VGGLRFLRGL RFLRLVRVLS
RLRPVRVMVR AAQVGVPRLA GPFAVFIMFF FAFALMGLQL FQGRFGQCSD ATRTSVETCK
GLMGPNEARV WVTPAVNFDD FGQALYAMLH LTALTDWTPV LYAGIDAPQE INTAAQFEAS
RANALFFVAY IVVQLWFVAP LFLAAVVDTF VDVAREMGGS VYERSSVVDA RLGVFVTEIS
TELSEEYEAP PAGASCRTPV FRMVTSDAFE ILIAVIIVIN TAYLALRHEG QTDEWDTHLL
VVNAVFVALY ALEALLKIVG LGWQYFWPLS WNTFDFGVLV LSVVGLVLEA AEGEATALSV
FRMFRLLRTV RLVARTGAMQ ALFHVATRAL VPLVLALAGV VAMTLPFAFM AMEGFGSHSL
SRGLDDNQEF RSLGQALLQF MRVFTGDTWG FLVESQLKGD GAAVALFAIY WVAVFMGGIH
VFTSIAFAAY GEATRFVQLY NRRETLHGFR MAFLDEAGGD LEQPIAPDAL RDVLAELPSP
LGLPLDARKA HAMGHFTRYD VAVRATGVYY GDVVRAFILT EVGHDIGTAT DGAGHGRVIS
SMARETEAAF TRGKSKSKGK R
//
