ID A0A0L0D3Z2_THETB Unreviewed; 428 AA.
AC A0A0L0D3Z2;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=CMGC/CK2 protein kinase {ECO:0000313|EMBL:KNC46028.1};
GN ORFNames=AMSG_00146 {ECO:0000313|EMBL:KNC46028.1};
OS Thecamonas trahens ATCC 50062.
OC Eukaryota; Apusozoa; Apusomonadida; Apusomonadidae; Thecamonas.
OX NCBI_TaxID=461836 {ECO:0000313|EMBL:KNC46028.1, ECO:0000313|Proteomes:UP000054408};
RN [1] {ECO:0000313|EMBL:KNC46028.1, ECO:0000313|Proteomes:UP000054408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50062 {ECO:0000313|EMBL:KNC46028.1,
RC ECO:0000313|Proteomes:UP000054408};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA Borenstein D., Chapman S., Chen Z., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D.,
RA Larson L., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA Burger G., Gray M.W., Holland P.W.H., King N., Lang F.B.F., Roger A.J.,
RA Ruiz-Trillo I., Lander E., Nusbaum C.;
RT "The Genome Sequence of Thecamonas trahens ATCC 50062.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily.
CC {ECO:0000256|RuleBase:RU000304}.
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DR EMBL; GL349433; KNC46028.1; -; Genomic_DNA.
DR RefSeq; XP_013763008.1; XM_013907554.1.
DR AlphaFoldDB; A0A0L0D3Z2; -.
DR STRING; 461836.A0A0L0D3Z2; -.
DR EnsemblProtists; KNC46028; KNC46028; AMSG_00146.
DR GeneID; 25559966; -.
DR eggNOG; KOG0668; Eukaryota.
DR OMA; NACINGR; -.
DR OrthoDB; 5472858at2759; -.
DR Proteomes; UP000054408; Unassembled WGS sequence.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14132; STKc_CK2_alpha; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR045216; CK2_alpha.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR24054; CASEIN KINASE II SUBUNIT ALPHA; 1.
DR PANTHER; PTHR24054:SF0; CASEIN KINASE II SUBUNIT ALPHA; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000313|EMBL:KNC46028.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000054408};
KW Serine/threonine-protein kinase {ECO:0000256|RuleBase:RU000304};
KW Transferase {ECO:0000313|EMBL:KNC46028.1}.
FT DOMAIN 39..319
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 321..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 381..428
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 64..91
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 381..419
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 69
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 428 AA; 48880 MW; 376F3F96B7BFD892 CRC64;
MTEQRVFEAR EHADYTERFD RAEFDVKRYR VTWTKTDRFK MGRKVGQGHF GEVFEAKDTQ
RKSKKVVAKM LKDTRKQKAK LRQEIKMLEY VRGGPNIVQL QDTVKDLNTG NKLLIFEKIN
YVKCRDLFPQ LDNEEVRYYA YELLRAIAYT HSIGVMHRDI KPSNILIDPR KRKLRLIDWG
KNIRGPGTRC YKSPELSLRY EYYDYSCDMW AFGCTFGSMI FLEHPLIRGK GSWFNQLLAT
VKIVGSDELF TYMRKINVVL DDDQMAALSG YPKKKWESFI DDDNRHRVTP EAIDLIANCV
LTDHVRRFTA TEAMAHPYFD AVRPSSSSAS SSRTHRHSKR NAADSAGSSS DSGRGGPAKP
DVASGSYSYY YESTYQYVSY TGSSSSSDDA PKARTGKSSR AGSSRASSSR PSKSASKAAS
KASKSRRR
//
