ID A0A0L0D8S5_THETB Unreviewed; 362 AA.
AC A0A0L0D8S5;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=GDT1 family protein {ECO:0000256|RuleBase:RU365102};
GN ORFNames=AMSG_03925 {ECO:0000313|EMBL:KNC47693.1};
OS Thecamonas trahens ATCC 50062.
OC Eukaryota; Apusozoa; Apusomonadida; Apusomonadidae; Thecamonas.
OX NCBI_TaxID=461836 {ECO:0000313|EMBL:KNC47693.1, ECO:0000313|Proteomes:UP000054408};
RN [1] {ECO:0000313|EMBL:KNC47693.1, ECO:0000313|Proteomes:UP000054408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50062 {ECO:0000313|EMBL:KNC47693.1,
RC ECO:0000313|Proteomes:UP000054408};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA Borenstein D., Chapman S., Chen Z., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D.,
RA Larson L., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA Burger G., Gray M.W., Holland P.W.H., King N., Lang F.B.F., Roger A.J.,
RA Ruiz-Trillo I., Lander E., Nusbaum C.;
RT "The Genome Sequence of Thecamonas trahens ATCC 50062.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU365102}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU365102}.
CC -!- SIMILARITY: Belongs to the GDT1 family. {ECO:0000256|ARBA:ARBA00009190,
CC ECO:0000256|RuleBase:RU365102}.
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DR EMBL; GL349448; KNC47693.1; -; Genomic_DNA.
DR RefSeq; XP_013759175.1; XM_013903721.1.
DR AlphaFoldDB; A0A0L0D8S5; -.
DR STRING; 461836.A0A0L0D8S5; -.
DR EnsemblProtists; KNC47693; KNC47693; AMSG_03925.
DR GeneID; 25563492; -.
DR eggNOG; KOG2881; Eukaryota.
DR OMA; YTHWIAT; -.
DR OrthoDB; 180756at2759; -.
DR Proteomes; UP000054408; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR001727; GDT1-like.
DR InterPro; IPR049555; GDT1-like_CS.
DR PANTHER; PTHR12608:SF1; TRANSMEMBRANE PROTEIN 165; 1.
DR PANTHER; PTHR12608; TRANSMEMBRANE PROTEIN HTP-1 RELATED; 1.
DR Pfam; PF01169; UPF0016; 2.
DR PROSITE; PS01214; UPF0016; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU365102};
KW Reference proteome {ECO:0000313|Proteomes:UP000054408};
KW Signal {ECO:0000256|RuleBase:RU365102};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU365102};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU365102}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|RuleBase:RU365102"
FT CHAIN 26..362
FT /note="GDT1 family protein"
FT /evidence="ECO:0000256|RuleBase:RU365102"
FT /id="PRO_5005537359"
FT TRANSMEM 109..131
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365102"
FT TRANSMEM 138..158
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365102"
FT TRANSMEM 170..187
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365102"
FT TRANSMEM 264..283
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365102"
FT TRANSMEM 303..323
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365102"
FT TRANSMEM 335..353
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU365102"
FT REGION 31..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 235..257
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..69
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 362 AA; 37558 MW; 33C38513628C5FE1 CRC64;
MRMTVRKNVV VVGMVLCLMA VGMLAEAAAT AGPGRAAGGT PPMSKADGMG KSKSKSKTVG
DDGGRVDRRR GGGAVSGGSK DGDVVGSAKG SSQTAAAAND DDGFVASSMA ALSMIIVSEI
GDKTFFIACI LSMRHPRMII FLAALAALGF MTAISAAMGW VVPLLVPREY THWIATILFA
IFGVRLLKEA HEMQGDEEND ELIEVQDELR EKHLMSSDSE EADVEAGLAG GATNFGISLQ
DAGPGTPRRP RSGKKARKGS AAPWYAMLVS PIFAQCFLLT LLAEWGDRSQ IATIIMAASR
NPYGVTFGGT LGHALCTGVA VVGGQVLSER ISVKSVSYVG GALFVLFAIT SLVQGPDDGG
SV
//
