ID A0A0L0D8Z1_THETB Unreviewed; 819 AA.
AC A0A0L0D8Z1;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=DNA repair protein REV1 {ECO:0000256|ARBA:ARBA00020399};
GN ORFNames=AMSG_04981 {ECO:0000313|EMBL:KNC48536.1};
OS Thecamonas trahens ATCC 50062.
OC Eukaryota; Apusozoa; Apusomonadida; Apusomonadidae; Thecamonas.
OX NCBI_TaxID=461836 {ECO:0000313|EMBL:KNC48536.1, ECO:0000313|Proteomes:UP000054408};
RN [1] {ECO:0000313|EMBL:KNC48536.1, ECO:0000313|Proteomes:UP000054408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50062 {ECO:0000313|EMBL:KNC48536.1,
RC ECO:0000313|Proteomes:UP000054408};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA Borenstein D., Chapman S., Chen Z., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D.,
RA Larson L., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA Burger G., Gray M.W., Holland P.W.H., King N., Lang F.B.F., Roger A.J.,
RA Ruiz-Trillo I., Lander E., Nusbaum C.;
RT "The Genome Sequence of Thecamonas trahens ATCC 50062.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DNA polymerase type-Y family.
CC {ECO:0000256|ARBA:ARBA00010945}.
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DR EMBL; GL349451; KNC48536.1; -; Genomic_DNA.
DR RefSeq; XP_013758643.1; XM_013903189.1.
DR AlphaFoldDB; A0A0L0D8Z1; -.
DR STRING; 461836.A0A0L0D8Z1; -.
DR EnsemblProtists; KNC48536; KNC48536; AMSG_04981.
DR GeneID; 25564491; -.
DR eggNOG; KOG2093; Eukaryota.
DR OMA; QPRLNFG; -.
DR OrthoDB; 169741at2759; -.
DR Proteomes; UP000054408; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.
DR GO; GO:0042276; P:error-prone translesion synthesis; IEA:InterPro.
DR CDD; cd17719; BRCT_Rev1; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 6.10.250.1490; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR025527; HUWE1/Rev1_UBM.
DR InterPro; IPR012112; REV1.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR45990; DNA REPAIR PROTEIN REV1; 1.
DR PANTHER; PTHR45990:SF1; DNA REPAIR PROTEIN REV1; 1.
DR Pfam; PF16589; BRCT_2; 1.
DR Pfam; PF00817; IMS; 1.
DR Pfam; PF11799; IMS_C; 1.
DR Pfam; PF14377; UBM; 1.
DR PIRSF; PIRSF036573; REV1; 2.
DR SMART; SM00292; BRCT; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR PROSITE; PS50172; BRCT; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 3: Inferred from homology;
KW DNA synthesis {ECO:0000256|ARBA:ARBA00022634};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000054408};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 25..113
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 253..434
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
FT REGION 686..819
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 765..788
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 819 AA; 87555 MW; EFA160E2CC260FED CRC64;
MERKRRKLAA QYDAERAANG GGVAQVSSIF DGVTIYVNGY TTPSAMTLRR YMLQHGGRYE
FQLHRSSVTH IIATTLPDAK IKFGPASDVI VHPQWIVDSI AAGKQLAVER YLLFANAYKS
MAGQQSLAES LGLATAAGES LAIAPELDRR TTAGDALTRR AAGAAGAADV EQAHPDLDGL
GMRRSKDEPI DPGLARLTTL GGGDFVQKFY SNSRLHFIST SRMASQEFLR KALAERYSTS
QPLAREAGAR QVIFHVDMDC FFASVALRDR PHLANAPVVV AHALNGSVES KSDIACASYA
ARARGISNGM FMGAARRKVP DLVVVPYEFD KYAAVSKALY RVFVAFSDKV QAVSVDEAYL
DMTGLGQPAE LASEMRAQIH ELSGCTASIG AGPNMLLARI ATSLAKPDGF RFLSHEHATF
EIDALPLRKL PGVGYKTVRK LAKAGITSCA ECRAQPRARL QALLGGSVGA KLYDTVRGLD
SGTVTLPGPR KSIGTEISWG VRFTDATGAE QFVRELAGEV GRRAVEAAMV GATLTLKIKQ
RHPDAPAEAS KFLGHGKVNS FSRSTTLAPP SSDAVALADA ALTLYRGLGF EATTVRGVGI
ALTRLSEVES ERRPALQPAA IDSQTTLSAE WHPPAVTGVG GRGAEGTVEL PTFSQLDPSV
IAELPAETRR ELEIVYRRRL AERKRDAGRG TLTQMARPTL PSRPASAAKT KPAPMVIVLD
GASGSDDDDF VSPPPQTRGS SDEGSGRDDG VDPEFLAALP SQLRREVEAD LKRTSPRKSG
RCDGGRKRQR GGAPSLSQIF HPSQAEGGRA ARRRHLLSG
//
