ID A0A0L0DA25_THETB Unreviewed; 450 AA.
AC A0A0L0DA25;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Tyrosine aminotransferase {ECO:0000313|EMBL:KNC49070.1};
GN ORFNames=AMSG_05029 {ECO:0000313|EMBL:KNC49070.1};
OS Thecamonas trahens ATCC 50062.
OC Eukaryota; Apusozoa; Apusomonadida; Apusomonadidae; Thecamonas.
OX NCBI_TaxID=461836 {ECO:0000313|EMBL:KNC49070.1, ECO:0000313|Proteomes:UP000054408};
RN [1] {ECO:0000313|EMBL:KNC49070.1, ECO:0000313|Proteomes:UP000054408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50062 {ECO:0000313|EMBL:KNC49070.1,
RC ECO:0000313|Proteomes:UP000054408};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA Borenstein D., Chapman S., Chen Z., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D.,
RA Larson L., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA Burger G., Gray M.W., Holland P.W.H., King N., Lang F.B.F., Roger A.J.,
RA Ruiz-Trillo I., Lander E., Nusbaum C.;
RT "The Genome Sequence of Thecamonas trahens ATCC 50062.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRNR:PIRNR000517, ECO:0000256|PIRSR:PIRSR000517-1};
CC -!- SIMILARITY: Belongs to the class-I pyridoxal-phosphate-dependent
CC aminotransferase family. {ECO:0000256|PIRNR:PIRNR000517}.
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DR EMBL; GL349453; KNC49070.1; -; Genomic_DNA.
DR RefSeq; XP_013758101.1; XM_013902647.1.
DR AlphaFoldDB; A0A0L0DA25; -.
DR STRING; 461836.A0A0L0DA25; -.
DR EnsemblProtists; KNC49070; KNC49070; AMSG_05029.
DR GeneID; 25564531; -.
DR eggNOG; KOG0259; Eukaryota.
DR OMA; CALDLCI; -.
DR OrthoDB; 5474881at2759; -.
DR Proteomes; UP000054408; Unassembled WGS sequence.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR InterPro; IPR005958; TyrNic_aminoTrfase.
DR NCBIfam; TIGR01265; tyr_nico_aTase; 1.
DR PANTHER; PTHR45744; TYROSINE AMINOTRANSFERASE; 1.
DR PANTHER; PTHR45744:SF2; TYROSINE AMINOTRANSFERASE; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR PIRSF; PIRSF000517; Tyr_transaminase; 1.
DR PRINTS; PR00753; ACCSYNTHASE.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Aminotransferase {ECO:0000313|EMBL:KNC49070.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRNR:PIRNR000517};
KW Reference proteome {ECO:0000313|Proteomes:UP000054408};
KW Transferase {ECO:0000313|EMBL:KNC49070.1}.
FT DOMAIN 77..439
FT /note="Aminotransferase class I/classII"
FT /evidence="ECO:0000259|Pfam:PF00155"
FT MOD_RES 285
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR000517-1"
SQ SEQUENCE 450 AA; 47790 MW; D584416836D8FE76 CRC64;
MSSSASAPSS SSSPAVAVAA ALASAALSVG MAMRWAARAA SAPAAPLQPS ITSMRTVNPI
RGVVERIDRT GNPEKEHIVL ALGDPTKFGN FAPPPSASAL LTNFEAKSHN GYTHSAGAPD
ARAAIAAAYS YPDVGNELRP NDVVIASGAS GAIYLAIQAL CNEGDEILVP SPGFALYGTA
ARSCGVVDVE YPLDPDNSWL VKLDALEARI TPRTRAIVIN NPSNPCGSVF PREHLEDILD
LAAKYNLPII ADEIYHGMVF KGVESLALAQ LRPRVPIFAI SGLAKRFMVP GWRVGWICVY
DYQGRAEPIR RALYQLAQIT LGANTLVQSV IPALLTETPT EYHEANNAKL EANARIVLDA
LASVAGIACT VPEGAMYTMA RIDFDAFDDS ITTDMHFVQG LLDEESVFAL PGSCFNAPNF
FRIVFAPPPE QLKEACARIA AFCARHAAAK
//
