ID A0A0L0DBF9_THETB Unreviewed; 2324 AA.
AC A0A0L0DBF9;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KNC49451.1};
GN ORFNames=AMSG_05458 {ECO:0000313|EMBL:KNC49451.1};
OS Thecamonas trahens ATCC 50062.
OC Eukaryota; Apusozoa; Apusomonadida; Apusomonadidae; Thecamonas.
OX NCBI_TaxID=461836 {ECO:0000313|EMBL:KNC49451.1, ECO:0000313|Proteomes:UP000054408};
RN [1] {ECO:0000313|EMBL:KNC49451.1, ECO:0000313|Proteomes:UP000054408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50062 {ECO:0000313|EMBL:KNC49451.1,
RC ECO:0000313|Proteomes:UP000054408};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA Borenstein D., Chapman S., Chen Z., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D.,
RA Larson L., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA Burger G., Gray M.W., Holland P.W.H., King N., Lang F.B.F., Roger A.J.,
RA Ruiz-Trillo I., Lander E., Nusbaum C.;
RT "The Genome Sequence of Thecamonas trahens ATCC 50062.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR EMBL; GL349455; KNC49451.1; -; Genomic_DNA.
DR RefSeq; XP_013757871.1; XM_013902417.1.
DR STRING; 461836.A0A0L0DBF9; -.
DR EnsemblProtists; KNC49451; KNC49451; AMSG_05458.
DR GeneID; 25564873; -.
DR eggNOG; KOG3627; Eukaryota.
DR eggNOG; KOG4297; Eukaryota.
DR OMA; SCVANTY; -.
DR OrthoDB; 3035244at2759; -.
DR Proteomes; UP000054408; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR CDD; cd00033; CCP; 15.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 17.
DR Gene3D; 4.10.1240.10; GPCR, family 2, extracellular hormone receptor domain; 1.
DR InterPro; IPR017868; Filamin/ABP280_repeat-like.
DR InterPro; IPR036445; GPCR_2_extracell_dom_sf.
DR InterPro; IPR001879; GPCR_2_extracellular_dom.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR19325; COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR19325:SF567; LOCOMOTION-RELATED PROTEIN HIKARU GENKI; 1.
DR Pfam; PF00084; Sushi; 10.
DR SMART; SM00032; CCP; 17.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 17.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS50194; FILAMIN_REPEAT; 1.
DR PROSITE; PS50227; G_PROTEIN_RECEP_F2_3; 2.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS50923; SUSHI; 14.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054408};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..2324
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5005537283"
FT TRANSMEM 1709..1730
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1739..1758
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1803..1827
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1891..1910
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1940..1965
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1990..2012
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2018..2039
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2046..2065
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2071..2089
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 228..277
FT /note="G-protein coupled receptors family 2 profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50227"
FT DOMAIN 271..332
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 335..397
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 400..461
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 464..522
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 506..593
FT /note="G-protein coupled receptors family 2 profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50227"
FT DOMAIN 525..584
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 587..645
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 648..712
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 715..773
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 841..898
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 967..1024
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1092..1149
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1152..1214
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1217..1275
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1278..1336
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT REPEAT 1390..1441
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REGION 173..195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2218..2324
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2218..2261
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2268..2324
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2324 AA; 239091 MW; FEADF9FDAD9E1FAA CRC64;
MRTMYQSTVF AAVACLLLAA SASAAIITKT ATSSTFYGSH NGAPWSGNRA QGAHCCGASQ
HSQYRIFYGF NLNIPSGHAV DGIQVSYEYI SSTTGFSACV NKDITLRTTS GSVILSSNAK
TGSSYFSSGT ISKGSSTDTW GLSGSASSIR SALNSGTFGV AVRATGFAEA SSSSGQIPLA
PTGGDSDGSR RVSTRAPTVG TWRVDVYNGD VTIKVWTHQL TCGATGPWPT TNAGSTATLG
CSSGYTGSRT RYCTTSGSWQ SESNGCTLVT NYCSLLTAPS NGILTASCSS KRSLGEVCGT
FQCNSGYQLS GSASRTCNAG PSWSGSAASC VKITNYCSLL TAPSNGYITS GSCSAQRSIG
ESCGTFQCNG GYSRSGDASR TCNAGPSWSG STASCGLITN YCPLLTAPAN GIITTSCTSK
RSVGESCGNF QCNGGYQLSG SMSRTCQSNA AWGGSAASCS PIPDYCPPPP AAPSNGVQGS
CSRTVGGTCS YSCNTGYNPG GGMTITCQSN GAWSGSPAAC NPTADYCPAL TAPTNGNAPA
SYSRTITSVA SPYTCNAGYD LSGSASRTCQ SDGTWSSTTP TCVLDTSYCG ARPATPANGN
AGSCGYSIGA SCTYGCNNGY EPTGSMTVTC NSGGAWSGSP ASCGLKTNYC PALTNPTNGQ
DPSSYSRVLG AVASPYTCNS GYIVTAGSTS RTCMANSAAS GVWSGTTPTC SIDNAHCSTA
PAPPPNFFID TCSAAQFGEC IYKCNNGYTR SGGDRYTCQP DTSWGGSLGT CSLTNNYCPA
LTIPANSNRG ACSGQLGSIC GPVTCNAGYS ISGSASRTCE DAGVSAGIWS GTATSCALIT
NYCTLPSTPS NGVLGACTRS IGGSCTYTCG NGYETSGTTT ITCQSGPTWS GSFGTCVKTS
GYCPVESAPA NGVAGTGCTG QIGTLCGPAS CNAGYNPSGT ATRTCNANNA VSGTWSGTTL
TCAIDPAYCT TPAAPANGAI GSCPLSIGSS CTASCSNGYS TGGLTSVTCE AGPAWSGVFG
ACSKYAGYCG ALPQPSNGVI PGCTGMLGSS CGAASCNAGY NLAGDATRNC IDNGPGFGSW
TGTSVSCNIE PNHCTPPPAP ANGALGTCIT SIGGSCSYTC DNGYEVSGTG TITCSAGPTW
STSFGTCVKS ANYCPAHPPL ADGSNPSCTG EIDEVCGTFT CNSGFDIVGS AERTCLNNGP
ITGIWSGTAP SCQVDNDYCP SGPAPPANGV KGSCARYLGG TCEYSCNAGY TNTGSSSLTC
TSGKTWLGAS PNCVPYNDYC PPKTSIEYGN APVCNNRINE VCGTFTCNPP FAIFGEKDRT
CGPDGDWIGD EPFCSSTDVS KSLVYSAQFI TVSADGPGWR IEIEPRTASN DTLAESQDFP
SVLLASTPPS VEAPSVAPAA VWSAAKSRFL IELTPQVVAT YSLNILLNGV VIGASPYTLV
VEAGVPAAPT TFATGRGLGI VVTDDDLFPQ NEVVRFAVFP HDQHGNVVPM ASNPATTPYV
ATLKGAGFAE GDVPIVYLAG ESGPTTGYVY EYSVPIGGLL TLSVTLDGLA IADSPWLVQV
RAICEPGKQA LQITGPCVPC EKDSYSAPDG RECLLCPDFM TSPSSSGSIG NCTCVRGYFE
NLAVVGADPS KRQCDACPVG ASCAGGNARP IADPGYHQVG DEFVSCPQPS ACLGAGQCAR
GYKGASCTDC VSGYYRLGDR CYKCNKAQAA FIATGIAFLL LLFVAALVYL NTRESHNRMY
TAAAFMIGFN SLQISAMYGE IDLRWHPVAE QFFNILSLAN LNIELTSPEC SVDFFGDPWL
IKWVLMLMLP IFMVFLLGVT FVLGLLYRLF ARTYGAKWAD RHPSYFPGAE NFFDAGGKAS
RSTLIKFRIG RLMSEAPLTP AALRQAVVRT FFQLFIFCYL PLTAVVLRYF ECERRAPGSS
EYVLATAPSV ECYDATYWSL FWMAIAGSIV YALGIPLFTY LLLYFRKRQM AEVNFMLRYG
FLVARFREKL YYFEITIMIR KLLVVGAVVA FGSPVQEAVM AALVLVISFG FVAHATPYLK
PFHNRLAMSA LFTSCIVLIG GTVDSNGLRD TLVLGGLGAN IFVIVYGIVV ETKNLIIREA
EDMVEVLELQ DTFEMGTFTI NEDEDTSMHY MVPTDDGNGK PPAGGMAKPA DSIVVSSSTD
DNTSMVTASM VSSSALHPSE SIFPSFALEC DTAPPVILPP GPPSPVSPVA PAMPAMPPPP
APAPPPPPPA PAAALPPPTP SMVAGVPPGG SLPPPPSSTN QPVVGPGGLV APLPPPKAAL
PPPPVGHGPP KPSRPKPSAH AGPPIPAPKP SGTSAAPFPP PKPY
//
