ID A0A0L0DFB8_THETB Unreviewed; 1658 AA.
AC A0A0L0DFB8;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Coronin {ECO:0000256|RuleBase:RU280818};
GN ORFNames=AMSG_12025 {ECO:0000313|EMBL:KNC51042.1};
OS Thecamonas trahens ATCC 50062.
OC Eukaryota; Apusozoa; Apusomonadida; Apusomonadidae; Thecamonas.
OX NCBI_TaxID=461836 {ECO:0000313|EMBL:KNC51042.1, ECO:0000313|Proteomes:UP000054408};
RN [1] {ECO:0000313|EMBL:KNC51042.1, ECO:0000313|Proteomes:UP000054408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50062 {ECO:0000313|EMBL:KNC51042.1,
RC ECO:0000313|Proteomes:UP000054408};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA Borenstein D., Chapman S., Chen Z., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D.,
RA Larson L., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA Burger G., Gray M.W., Holland P.W.H., King N., Lang F.B.F., Roger A.J.,
RA Ruiz-Trillo I., Lander E., Nusbaum C.;
RT "The Genome Sequence of Thecamonas trahens ATCC 50062.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the WD repeat coronin family.
CC {ECO:0000256|ARBA:ARBA00009482, ECO:0000256|RuleBase:RU280818}.
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DR EMBL; GL349464; KNC51042.1; -; Genomic_DNA.
DR RefSeq; XP_013756556.1; XM_013901102.1.
DR EnsemblProtists; KNC51042; KNC51042; AMSG_12025.
DR GeneID; 25569940; -.
DR eggNOG; KOG0303; Eukaryota.
DR eggNOG; KOG0446; Eukaryota.
DR eggNOG; KOG1445; Eukaryota.
DR OrthoDB; 5474889at2759; -.
DR Proteomes; UP000054408; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0031982; C:vesicle; IEA:UniProtKB-SubCell.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd08771; DLP_1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR015505; Coronin.
DR InterPro; IPR015048; DUF1899.
DR InterPro; IPR022812; Dynamin.
DR InterPro; IPR001401; Dynamin_GTPase.
DR InterPro; IPR045063; Dynamin_N.
DR InterPro; IPR000375; Dynamin_stalk.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR030381; G_DYNAMIN_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR10856; CORONIN; 1.
DR PANTHER; PTHR10856:SF20; CORONIN-7; 1.
DR Pfam; PF08953; DUF1899; 1.
DR Pfam; PF01031; Dynamin_M; 1.
DR Pfam; PF00350; Dynamin_N; 1.
DR Pfam; PF00400; WD40; 4.
DR Pfam; PF16300; WD40_4; 2.
DR PRINTS; PR00195; DYNAMIN.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM01166; DUF1899; 2.
DR SMART; SM01167; DUF1900; 2.
DR SMART; SM00053; DYNc; 1.
DR SMART; SM00320; WD40; 8.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 2.
DR PROSITE; PS51718; G_DYNAMIN_2; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 4.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 3.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000054408};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|RuleBase:RU280818};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 61..321
FT /note="Dynamin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51718"
FT REPEAT 776..818
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 824..866
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1273..1307
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1323..1365
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1092..1194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1629..1658
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1096..1118
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1167..1190
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1658 AA; 178897 MW; E10B6BAEDCA39171 CRC64;
MLAGATGIAA AAGWQRTFAA RRTKKKSAGV AKEAVYNETD PEAVIPTLVR LEKVLGKEKA
KLELPKIVVV GNQSSGKSSV LEAVAGFDFL PKSTSMCTTR PLELNLLRSD SGTWAEFDDG
RKIFDFEQVE AILREKNQDE EFSELPVTMS IYAPHVYNVS LIDLPGYIHA VRAGQSPELP
ERIAALCQKY ISDPNNIIVA VASAADDVAM SMGIKNAQAV DANMDRSLGV LTKMDLIKSR
KHIHSILRNE DYPLGLGYVG VRCRSQKELE DGKSFDDVLR IEEAFIRRAK LRDVGDLRLG
IPTLRRVLSE EQLNKVAADF PRILAELDQH IDDVAKDEQF LLAISAETDL RNIARELEKL
VLKFSPLSPE RLEFEAQVRD TIGDIVHNAW FDAMDKFFEF SDPPSPLASP QLSARLTEAY
KPTNDELHVQ KTARRALTDV DFEPESHFVD RRGKFERALV FGTGTPDKID DATLARLGDH
ALIDGALAPF YKYVFPENAN RARPVWQEAL EDSVDAVLSD AHLVDRCRRA TVDQLLEFVD
RTAHAGTGRE SRLALHFFRY LVKRISTEIN SDGLSSHIEG MIAREKRATV SYPVLMAETA
ELLRSPKTET GLGFWGALTN SAKWPLVIPL YGQVFTSAYF GAVIDRSTSD VFRSLAVEML
NPLIIEAIHY SLNLFKGHKI RRESKRQLQY LNQLKKYRAI IASAQARYTP SKPAPGSASS
SSSYSELRTT SLAGDCNEVA ASGKYVAFGG SSARSISFLP VGGSGRFGSG QGVPGVAGHS
RNISALDFSP FHDALLVTAA EDGSVKIWEL GEGKASVSET ASAWSASQKR IQALAFNPVA
DGVLATAAAD GVVKVWDVNA EAELCAAPSI ECQPQSLAWD YAGATLVVTA KDKTVRVYDL
RASADGPVAS GPGHDGIKAT RVTWMGDSSR FVTTGFDKYR SREVRVYDMA SSLDAPISKT
KMDSSSGILM PLYDADTKLL FLGGKGDVAL RFYEDDGGKL LEAGSVGSRE QISGLALAPK
RVLNVWDCEV ARVLKLTAAG AVVPVSYKVP RKSYAKFHPE LYPETRGTTP GATAPEWASG
ANGSVALVSL QPEGERPTPS LPSSSMKSTS SGKTNSAGKT PPPVAARAPV ARKWGAGSGG
GGSKWGAGGS GGGGGSGGSK WGAKRSSWSL KAKEEAPAES EKESDPDAPP EGMREVVVPK
NVVRVSKFRH IVGSETKKEL WTTGLRINDN FSVDSSMVAA SDALVAVPWK GAGGVIGVFP
RSHVGRVDVD MPTISQSSIF NAFDFSPFNG NLLATGSDDG RVGLWEIPST GLAAPLTEAS
ATMEGHRHRV TWLTWAPYVE NLLATGSFDS TVRLWDVEQQ ACLVSMDSFE AEPTGVAFAY
DSATIASSAR DKKLRLHDPR ADGSVVASVA DAHVGVKPFK LVWLGAGDKL ATVGFGERSK
REIKVWDMRA LDAPVATKPL TTSSNLALPF YDVQTGVLFL AGKGDGSINT FEINEKGIHE
LAPYTATNPQ SGLALLPKSC VDVAACEFAS FVKLSGSAIS SVTFKVPRSR KELFQDDVFV
PVPGFEPAAT AAVFLDAVPG APPLHDMRPE GMPLLSEAAP TTKKPVRKWV PTTVEKVDTR
SAKDKLMDSF ESKLNPYQED ASSSRPAANR DAAAAEDW
//
