ID A0A0L0DGJ4_THETB Unreviewed; 694 AA.
AC A0A0L0DGJ4;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=glycerol kinase {ECO:0000256|ARBA:ARBA00012099};
DE EC=2.7.1.30 {ECO:0000256|ARBA:ARBA00012099};
DE AltName: Full=ATP:glycerol 3-phosphotransferase {ECO:0000256|ARBA:ARBA00043149};
GN ORFNames=AMSG_07321 {ECO:0000313|EMBL:KNC51310.1};
OS Thecamonas trahens ATCC 50062.
OC Eukaryota; Apusozoa; Apusomonadida; Apusomonadidae; Thecamonas.
OX NCBI_TaxID=461836 {ECO:0000313|EMBL:KNC51310.1, ECO:0000313|Proteomes:UP000054408};
RN [1] {ECO:0000313|EMBL:KNC51310.1, ECO:0000313|Proteomes:UP000054408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50062 {ECO:0000313|EMBL:KNC51310.1,
RC ECO:0000313|Proteomes:UP000054408};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA Borenstein D., Chapman S., Chen Z., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D.,
RA Larson L., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA Burger G., Gray M.W., Holland P.W.H., King N., Lang F.B.F., Roger A.J.,
RA Ruiz-Trillo I., Lander E., Nusbaum C.;
RT "The Genome Sequence of Thecamonas trahens ATCC 50062.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Polyol metabolism; glycerol degradation via glycerol kinase
CC pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
CC {ECO:0000256|ARBA:ARBA00005190}.
CC -!- SIMILARITY: Belongs to the FGGY kinase family.
CC {ECO:0000256|ARBA:ARBA00009156}.
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DR EMBL; GL349466; KNC51310.1; -; Genomic_DNA.
DR RefSeq; XP_013756232.1; XM_013900778.1.
DR AlphaFoldDB; A0A0L0DGJ4; -.
DR STRING; 461836.A0A0L0DGJ4; -.
DR EnsemblProtists; KNC51310; KNC51310; AMSG_07321.
DR GeneID; 25566259; -.
DR eggNOG; KOG2517; Eukaryota.
DR OMA; VQWMRDQ; -.
DR OrthoDB; 2734344at2759; -.
DR UniPathway; UPA00618; UER00672.
DR Proteomes; UP000054408; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004370; F:glycerol kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR018483; Carb_kinase_FGGY_CS.
DR InterPro; IPR018485; FGGY_C.
DR InterPro; IPR018484; FGGY_N.
DR PANTHER; PTHR10196:SF69; GLYCEROL KINASE; 1.
DR PANTHER; PTHR10196; SUGAR KINASE; 1.
DR Pfam; PF02782; FGGY_C; 1.
DR Pfam; PF00370; FGGY_N; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS00933; FGGY_KINASES_1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:KNC51310.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054408};
KW Transferase {ECO:0000313|EMBL:KNC51310.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 671..690
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 6..259
FT /note="Carbohydrate kinase FGGY N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00370"
FT DOMAIN 269..448
FT /note="Carbohydrate kinase FGGY C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02782"
FT COILED 545..656
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 694 AA; 71591 MW; 20A3AC72E60931C1 CRC64;
MADQKYAAAL DVGTSSVRFI VFQHDGTVAA SVAQEVPTAT PQPGWVEQDA EAVLQACVAV
MAAGVAAAEA EASIAPEAIG CVGVTNHRES TVAWSAASGQ PLAPMIIWSD VRTAAIVDRI
AAEAGGERAL AAITGLPMST YFSAFKMRWL LENVPAVADA AADGDLRLST VDAFVIARLT
SGDVYVSDVT NASRTCLMDL SSLKWSSEAL ELFDLPPTAL PTIVSSAEEY GRIDPAVVPD
LAHVPLAGCL GDQQAALVGQ RCFAAGLAKN TYGTGCFMLL NVGTTPRFSS AGLLGTVAYQ
LGPDAPVHYA LEGSVAVAGL GVRWARDNLG IIDSPKQINE LATAVDDTAG VVFVPAFSGL
LRRTGLRTLA AHIARAILEA PCFRTAEVLV AMAADAPDVA LSSLRVDGGM AASDLLLQTQ
ADLIGIPVER PAMLETTALG AAFAAGLATG VWASPDAFAA ATESQLTIVA PSYAETDSVA
VAAIASRKAA WTHAVAQAKL PADYDEAASD AIKAQLADQI EVAQALQLLL ASESEANNEY
AMTKVPELEA QVAAARREAD ALRSQVATAD ASAREVTAAK SELEARLEVE VKNVAQLTGQ
VEAQSQVLAA LAARYKALEK EAGEHRTAAA DAAAAVDRMT AELETAARAV HSANKDVVSH
AALAAAAHTR ALVALGGLGV ALTAGLGLFL RFRR
//
