ID A0A0L0DHB7_THETB Unreviewed; 997 AA.
AC A0A0L0DHB7;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=WW domain-containing protein {ECO:0000259|PROSITE:PS50020};
GN ORFNames=AMSG_12074 {ECO:0000313|EMBL:KNC51585.1};
OS Thecamonas trahens ATCC 50062.
OC Eukaryota; Apusozoa; Apusomonadida; Apusomonadidae; Thecamonas.
OX NCBI_TaxID=461836 {ECO:0000313|EMBL:KNC51585.1, ECO:0000313|Proteomes:UP000054408};
RN [1] {ECO:0000313|EMBL:KNC51585.1, ECO:0000313|Proteomes:UP000054408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50062 {ECO:0000313|EMBL:KNC51585.1,
RC ECO:0000313|Proteomes:UP000054408};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA Borenstein D., Chapman S., Chen Z., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D.,
RA Larson L., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA Burger G., Gray M.W., Holland P.W.H., King N., Lang F.B.F., Roger A.J.,
RA Ruiz-Trillo I., Lander E., Nusbaum C.;
RT "The Genome Sequence of Thecamonas trahens ATCC 50062.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL349468; KNC51585.1; -; Genomic_DNA.
DR RefSeq; XP_013756038.1; XM_013900584.1.
DR AlphaFoldDB; A0A0L0DHB7; -.
DR STRING; 461836.A0A0L0DHB7; -.
DR EnsemblProtists; KNC51585; KNC51585; AMSG_12074.
DR GeneID; 25569989; -.
DR eggNOG; KOG4177; Eukaryota.
DR OrthoDB; 5703864at2759; -.
DR Proteomes; UP000054408; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00201; WW; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR24166:SF48; ANKYRIN REPEAT DOMAIN 29; 1.
DR PANTHER; PTHR24166; ROLLING PEBBLES, ISOFORM B; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF13857; Ank_5; 1.
DR Pfam; PF00397; WW; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 5.
DR SMART; SM00456; WW; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054408};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 735..759
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 800..821
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 833..855
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 208..240
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 340..372
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 592..626
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT REGION 1..105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 122..169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 904..997
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..79
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 153..169
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 922..947
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 962..981
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 997 AA; 100302 MW; 14185D3B73D2DF10 CRC64;
MSDSSLPETR PGSGGAVSSA SSASSVSSAS SGSAVSAADV GTGTGTGSDT GSGSGSGSAA
GSAAGFGSGS GSGSAAGSAA GSAAGSAAGS AAGADAGSAA GSAAGSAAGS AAGSAAGSAA
GSAAGSAAGA DDGSAPGSEA DAGSDSGSEA DAELADSPSS SSSASLPSPS RAADVQLEFL
AACTMGDVAA VASALATGAV DLSVTDSDGY SGLHCAVQAG SSDVVAALLA AGADVNARGP
RGATALHEAA AAGADDIAAL LVASAAIELD ARNNAGQTPQ DVAVAKGRTA VVAVLSDAAE
ARTAERVLAA AASGDAAALA TMFDAHASAT HPLVHIQDSS GATPLALAAE AGSVAAVKLL
IQKGADLEAS VEIPAFASPL SRALVAGHLD VATILVEAGA SLEYPLGAAR TPLDDAKALG
SRELLAQVEE WLAGASDTAD AETEAKSPAA MLASNTAYAP ASPAADAQVA GIEDKLMANL
ARREALLAAA SVRSLSAAES DELADLEANI TTFGGFVKRA TGRDLVGEFA ARGSASISSR
PARAGGEYKT AISPGGVRIV WANDAYDRDQ ADARQPPADW LVDDNPGASK ATPLPPGWVA
CMSQRKGVPF YHNIVTGTST WERPYNHEAE RAVVPAITRK RDAFCARLAA RAAAAWGLPL
LQEYALFGES YSQADRHHAF STAHSLEIAR RESTRDISAQ KSQRVQGLML SNTLLLGVWF
SFVVEGIIPP ETSPAMVFIY SLGLSLGFAA LFLSVWFAMK LQSRMTKYNV AKITQVYTCG
NIHPSFRDYY ECHCTTLNTL AIWCFYSGTV FLIGAACVLT YTRFALTFDS PSAGVIFVVA
CGLTVAALLV LGIIFPTSTR LTPEEAEEQA TKAAAKAARA AGMSAHRPPP TAWEDVSDNS
LFLSADSDAG GARPTRPVAR RGFGAGEDDE PGADGRGTSK AVRFHADDPD PAVVPVLMSD
YSSRSDGESL SLYSEIESTT PRSPVPRRRR HRRRHRP
//
