ID   A0A0L0DHJ9_THETB        Unreviewed;       659 AA.
AC   A0A0L0DHJ9;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=PH domain-containing protein {ECO:0000259|PROSITE:PS50003};
GN   ORFNames=AMSG_07759 {ECO:0000313|EMBL:KNC51695.1};
OS   Thecamonas trahens ATCC 50062.
OC   Eukaryota; Apusozoa; Apusomonadida; Apusomonadidae; Thecamonas.
OX   NCBI_TaxID=461836 {ECO:0000313|EMBL:KNC51695.1, ECO:0000313|Proteomes:UP000054408};
RN   [1] {ECO:0000313|EMBL:KNC51695.1, ECO:0000313|Proteomes:UP000054408}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 50062 {ECO:0000313|EMBL:KNC51695.1,
RC   ECO:0000313|Proteomes:UP000054408};
RG   The Broad Institute Genome Sequencing Platform;
RA   Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA   Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA   Borenstein D., Chapman S., Chen Z., Freedman E., Gellesch M., Goldberg J.,
RA   Griggs A., Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D.,
RA   Larson L., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA   Burger G., Gray M.W., Holland P.W.H., King N., Lang F.B.F., Roger A.J.,
RA   Ruiz-Trillo I., Lander E., Nusbaum C.;
RT   "The Genome Sequence of Thecamonas trahens ATCC 50062.";
RL   Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   EMBL; GL349469; KNC51695.1; -; Genomic_DNA.
DR   RefSeq; XP_013755824.1; XM_013900370.1.
DR   AlphaFoldDB; A0A0L0DHJ9; -.
DR   STRING; 461836.A0A0L0DHJ9; -.
DR   EnsemblProtists; KNC51695; KNC51695; AMSG_07759.
DR   GeneID; 25566608; -.
DR   OrthoDB; 164125at2759; -.
DR   Proteomes; UP000054408; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   CDD; cd00821; PH; 2.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 3.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR14336:SF8; DUAL ADAPTER FOR PHOSPHOTYROSINE AND 3-PHOSPHOTYROSINE AND 3-PHOSPHOINOSITIDE; 1.
DR   PANTHER; PTHR14336; TANDEM PH DOMAIN CONTAINING PROTEIN; 1.
DR   Pfam; PF00169; PH; 3.
DR   SMART; SM00233; PH; 3.
DR   SUPFAM; SSF50729; PH domain-like; 3.
DR   PROSITE; PS50003; PH_DOMAIN; 3.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054408}.
FT   DOMAIN          119..218
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   DOMAIN          258..356
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   DOMAIN          416..518
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   REGION          370..414
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          563..659
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        376..399
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        644..659
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   659 AA;  69788 MW;  1E6BFAAF5329664A CRC64;
     MGDSADGLAD APPPPASFVE AGSVLAVGAV GDGVLLEDAP PPPPSFLGSP SVLGGGGGSG
     VNFLDVGDID VDTFGMPMPP PPECEFNAAP DDDDDLSAGI PPVYDDRIAS IEAAAGSDGL
     LKAGWVYKRG GGKLRSPWQK RFLVLTLDSL TYAPSETKPI KGRINMAHVK KVRYSNDPGE
     MGKRCGIVVV TLPRTYYFAP ETPDELMEWM RLLSQAAKRH RYLRIKARSE ANNEELLSAS
     EEDDESEFSA SSDWAAEEVI KEGNVLKRAP VKIKWAPCWL SLSNKKITYG SANNSRVAGM
     IYTKDIEGVL KTIGQREVGE QANCLSLYTA DRTYFFSAPS EVELHKWLDV IRIAQEQARA
     GASDSIADAG AASSATPAPA GSSPPKSGSG ASLAAAGSSG SLVTGDEDED EDDDGEIVLE
     GLLVKRGGRR SSWRTRWFTV SRQKLTYSAS KEKGLKGEFL IRDIKTVLRD IPLKVKRELD
     KTSRVGITVA TVDRTYYLAS DDERTLDAWY RVLHRLHRDR KKGRKRPLDF YRQLGTSAEV
     DVDTLNSADR AALGSAELDV STSASASPAA GNDEPPPVKV DTAATPGAAS DGGDADESAS
     DADAPAESDR NGNDDAPAVQ VDKGDGGGTG EAADGAADDG NGNNAAASDD SESSSTDLV
//