ID A0A0L0DI14_THETB Unreviewed; 1236 AA.
AC A0A0L0DI14;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=ZZ-type domain-containing protein {ECO:0000259|SMART:SM00291};
GN ORFNames=AMSG_07188 {ECO:0000313|EMBL:KNC50938.1};
OS Thecamonas trahens ATCC 50062.
OC Eukaryota; Apusozoa; Apusomonadida; Apusomonadidae; Thecamonas.
OX NCBI_TaxID=461836 {ECO:0000313|EMBL:KNC50938.1, ECO:0000313|Proteomes:UP000054408};
RN [1] {ECO:0000313|EMBL:KNC50938.1, ECO:0000313|Proteomes:UP000054408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50062 {ECO:0000313|EMBL:KNC50938.1,
RC ECO:0000313|Proteomes:UP000054408};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA Borenstein D., Chapman S., Chen Z., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D.,
RA Larson L., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA Burger G., Gray M.W., Holland P.W.H., King N., Lang F.B.F., Roger A.J.,
RA Ruiz-Trillo I., Lander E., Nusbaum C.;
RT "The Genome Sequence of Thecamonas trahens ATCC 50062.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the MT-A70-like family. {ECO:0000256|PROSITE-
CC ProRule:PRU00489}.
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DR EMBL; GL349463; KNC50938.1; -; Genomic_DNA.
DR RefSeq; XP_013756635.1; XM_013901181.1.
DR AlphaFoldDB; A0A0L0DI14; -.
DR STRING; 461836.A0A0L0DI14; -.
DR EnsemblProtists; KNC50938; KNC50938; AMSG_07188.
DR GeneID; 25566165; -.
DR eggNOG; KOG2098; Eukaryota.
DR OMA; PRESCIC; -.
DR OrthoDB; 179166at2759; -.
DR Proteomes; UP000054408; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:InterPro.
DR GO; GO:0090304; P:nucleic acid metabolic process; IEA:UniProt.
DR CDD; cd02249; ZZ; 1.
DR Gene3D; 3.30.60.90; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR007757; MT-A70-like.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR000433; Znf_ZZ.
DR InterPro; IPR043145; Znf_ZZ_sf.
DR PANTHER; PTHR12829; N6-ADENOSINE-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR12829:SF9; N6-ADENOSINE-METHYLTRANSFERASE WITH ZZ-TYPE ZINC-BINDING DOMAINS-RELATED; 1.
DR Pfam; PF05063; MT-A70; 1.
DR Pfam; PF00569; ZZ; 1.
DR SMART; SM00291; ZnF_ZZ; 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51143; MT_A70; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000054408};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 956..1002
FT /note="ZZ-type"
FT /evidence="ECO:0000259|SMART:SM00291"
FT DOMAIN 1013..1056
FT /note="ZZ-type"
FT /evidence="ECO:0000259|SMART:SM00291"
FT REGION 52..184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 207..294
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 548..615
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 691..738
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..83
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 146..166
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 557..571
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 699..726
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1236 AA; 130771 MW; 424E8949013A3882 CRC64;
MPTVAEMVEE ERGRRRRRGK VVVYNEEALL KSQWRDSEKM KKAMKVEEIE AKKVRRAHAR
RRAAEKKKKA AERRRKAKAA AAARRKKKAA EAAAAAAAAA AAAAAMDPGD AATLQDSVGS
TVGGQKVDAG SGAQASAAGM GAGSSGAASV SASASAASTP AATPSRDSRN ARHPRHPQHG
YVIYDDYGLP IVVDQLPKRV RKRAPAAVTS AQAAAQNRPM VARKLLDVPS PPTTPGRRAG
LARPDRNSPR LSAKASGSAP PSASKGKGKS KGKSKGKGKA SVALGANGSG GPPMKDVLRR
FKRWTKTYLT NAVDVLPQTA MPSTVIVGEN AVVRHGSSVF LDRITAYNEA ELKDDPVALA
LDKALSCFSE DNPLTTLPGF SPRSLWYPSL SEVLDAAFGG SVEQMARSLS AVDASTRAHQ
AALRKGLIRP RTLTATVSAP RSSAPEQALA PMDVVTAPPQ RSQPPPVSTR TRAVQTEITH
VQSKTARRWD DVQRVSSELD AGIIPKNVYA DQLNPKRTFE HFISRSPTKT ATRPTAPLAT
IAATVATAAP AAGEPKDSSV NTLTSAMNPA PSDALRNPAA LSTGKRGRDE ADEATGTAAG
HGPGPVPKKA KPMEGPQLKL SAPMAAPAPG PVAETPAPSM TVAEMVAAAT AAATTAAAVL
GTGGPAGRST VSATPAGAAV PPRACIASTA SVSSAPPLAA ESRPPPPPPP PPPSLPLPPP
PPSVPTGVEA AMANEDGGPK MMLKGEERWT SGTYVNCDVR YFNLKCLGKF DMVYIDPPWR
IRGNQVMPED GHIFSNSQRR RNYDTLSNTD IYDLEIGELV DTGLIFMWTV TSQLKVALQC
LEHWGFDFID KITWVRLTHR DNVAMGLGYY FLHSSEICLV GAKSRPGARL EIIPKISNDL
LFARVGKPSE KPVEMYDIME RMMPGGRKIE IFARNNNLRR GWLSVGNLLG PNFEYVKDRV
MCDECAAGIP IGTRRFKSRS VPNRDVCAEC FAGTGEPAHN YFELEHAIAV MVFHNNYTCD
MCGMNPICGI RFSCSRCEYD LCEGCFDFSV TTWAAAAGAA SPSAAEPSIF HTPDKKSTRV
RSATHDPAHA FLAYEDMDDS GGLPKHHARC TSCFDFPLSA TGSSASTANG SRSAKSASSA
MRLLDRPRES CICPRCVIDV HATERALVRE LPSVRVADRA LVLAQRAASA AAADEIIHDA
VSDVAQGVAA DAVADAVAET MIDDAAAAVA AESMAG
//
