ID A0A0L0DI50_THETB Unreviewed; 1165 AA.
AC A0A0L0DI50;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Fatty acyl-CoA reductase 1 {ECO:0000313|EMBL:KNC50978.1};
GN ORFNames=AMSG_06945 {ECO:0000313|EMBL:KNC50978.1};
OS Thecamonas trahens ATCC 50062.
OC Eukaryota; Apusozoa; Apusomonadida; Apusomonadidae; Thecamonas.
OX NCBI_TaxID=461836 {ECO:0000313|EMBL:KNC50978.1, ECO:0000313|Proteomes:UP000054408};
RN [1] {ECO:0000313|EMBL:KNC50978.1, ECO:0000313|Proteomes:UP000054408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50062 {ECO:0000313|EMBL:KNC50978.1,
RC ECO:0000313|Proteomes:UP000054408};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA Borenstein D., Chapman S., Chen Z., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D.,
RA Larson L., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA Burger G., Gray M.W., Holland P.W.H., King N., Lang F.B.F., Roger A.J.,
RA Ruiz-Trillo I., Lander E., Nusbaum C.;
RT "The Genome Sequence of Thecamonas trahens ATCC 50062.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GPAT/DAPAT family.
CC {ECO:0000256|ARBA:ARBA00007937}.
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DR EMBL; GL349464; KNC50978.1; -; Genomic_DNA.
DR RefSeq; XP_013756449.1; XM_013900995.1.
DR AlphaFoldDB; A0A0L0DI50; -.
DR STRING; 461836.A0A0L0DI50; -.
DR EnsemblProtists; KNC50978; KNC50978; AMSG_06945.
DR GeneID; 25565999; -.
DR eggNOG; KOG1221; Eukaryota.
DR eggNOG; KOG3730; Eukaryota.
DR OMA; EWNLETN; -.
DR OrthoDB; 1434498at2759; -.
DR Proteomes; UP000054408; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008374; F:O-acyltransferase activity; IEA:InterPro.
DR GO; GO:0044255; P:cellular lipid metabolic process; IEA:InterPro.
DR CDD; cd05236; FAR-N_SDR_e; 1.
DR CDD; cd07993; LPLAT_DHAPAT-like; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013120; Far_NAD-bd.
DR InterPro; IPR022284; GPAT/DHAPAT.
DR InterPro; IPR045520; GPAT/DHAPAT_C.
DR InterPro; IPR041728; GPAT/DHAPAT_LPLAT.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR PANTHER; PTHR12563:SF17; DIHYDROXYACETONE PHOSPHATE ACYLTRANSFERASE; 1.
DR PANTHER; PTHR12563; GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE; 1.
DR Pfam; PF01553; Acyltransferase; 1.
DR Pfam; PF19277; GPAT_C; 1.
DR Pfam; PF07993; NAD_binding_4; 1.
DR SMART; SM00563; PlsC; 1.
DR SUPFAM; SSF69593; Glycerol-3-phosphate (1)-acyltransferase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000054408};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 660..790
FT /note="Phospholipid/glycerol acyltransferase"
FT /evidence="ECO:0000259|SMART:SM00563"
SQ SEQUENCE 1165 AA; 123744 MW; 48E0958BD8417148 CRC64;
MVRFVTEHYA GKGVLLTGAT GFIGKVMLEK LLREVPDLAS IDVLIRGRGA SAPAAARLET
EVRDSPAFDL LRALWPPPYG LDRELVAPAR AGLVAPDVAA HLTATYPSFN AYFAAKVRPL
AGDLTLDRLG LDDATVTRLL ADVHVVLSVA ASVAFDNPLP EAIALNIRGQ LALFDIMMAS
NILVSFTHIS TAYVGSNRDD GLVPEGVLPL PAGMVADPEV EYANLIATPP DELIARQATI
IGKYPNTYTY TKALAERLLH ARLLAAAAHR NVLLVTIRPT IVGAAYAEPF PGWVDAVSAG
GALYLFAGVG VLQFGNGDAS LIGDQIPVDY VSNFVLTAAP TLLATGAAVV PATGAGHPAQ
EFIFHSGSSA LNPVTWKTTG EAVISYWNEN APDAGFRPAE FLFHSRLVAD FRRLVSYATP
AAIASLYAHI VPIKANTKAA LQARGLSSQA SFLISAFRRF MTHEWIFDMT HSDALLLAPL
AAADTAQTWR VDVRDLHWPT FISQFAYGLH RFVLGEPVRL ASPPAYRPHS VLDEAILSTR
AGHALDTAAW AASAPLSISH AGDGVPVSAS DVRHVVLASP RLRATLRSLA SSKAHYRKLK
AAARAELDRM AADMAPSAMR FAAWLLRLLC TRLYATVSFN SWGAEKVLGL VASSAADLGI
VYVPSHRSYL DFILLSYLCF QLGLPVPHVA ATGDFLSTPM ISGLMRAAGA FFIRRSGKTS
DPVYRAVLAE YMASVINHGA ALEFFVEGTR SRTGKSLPPR LGLLTQLAQL QACGALNRSL
VFVPVSIAFE RLIEAPLYGR ELDGQPKTPE TFLGALAGVR AILNNDYGRV AVEFGEPLHL
ADALPLGAES CEDELRAGVA AFATRISHRL DAGMTLFPTH LLAASLLAAP GPVAVNDLVS
ATDALRAAVE LRTGASLRRA DMLPIVASGS ITRAAKLLAP FVVSCETTAR LAPADPQARL
VLATYKNSLL RVFALDAVVA LAMRGGLVRR ALAARAVRLA AILGAELLLA NHVPAPENLA
DEHWLDDYVA TEFVGLVARL AVFSPLTLGY IDGSPGPLPS AEPLAALVAP SPLATAPWSE
PRAAVMDRAR ALAALGDRYE SRSTETLKAA LAWLIKAGLV VPSIRKSGRE ALSLARGARD
ILEDTHALLA DLTTARGGAA QLSKL
//
