ID A0A0L0DJ37_THETB Unreviewed; 1096 AA.
AC A0A0L0DJ37;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=STE/STE11 protein kinase {ECO:0000313|EMBL:KNC52086.1};
GN ORFNames=AMSG_00914 {ECO:0000313|EMBL:KNC52086.1};
OS Thecamonas trahens ATCC 50062.
OC Eukaryota; Apusozoa; Apusomonadida; Apusomonadidae; Thecamonas.
OX NCBI_TaxID=461836 {ECO:0000313|EMBL:KNC52086.1, ECO:0000313|Proteomes:UP000054408};
RN [1] {ECO:0000313|EMBL:KNC52086.1, ECO:0000313|Proteomes:UP000054408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50062 {ECO:0000313|EMBL:KNC52086.1,
RC ECO:0000313|Proteomes:UP000054408};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA Borenstein D., Chapman S., Chen Z., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D.,
RA Larson L., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA Burger G., Gray M.W., Holland P.W.H., King N., Lang F.B.F., Roger A.J.,
RA Ruiz-Trillo I., Lander E., Nusbaum C.;
RT "The Genome Sequence of Thecamonas trahens ATCC 50062.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL349436; KNC52086.1; -; Genomic_DNA.
DR RefSeq; XP_013762091.1; XM_013906637.1.
DR AlphaFoldDB; A0A0L0DJ37; -.
DR STRING; 461836.A0A0L0DJ37; -.
DR EnsemblProtists; KNC52086; KNC52086; AMSG_00914.
DR GeneID; 25560689; -.
DR eggNOG; KOG0198; Eukaryota.
DR eggNOG; KOG0586; Eukaryota.
DR OrthoDB; 1342069at2759; -.
DR Proteomes; UP000054408; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00060; FHA; 1.
DR CDD; cd00063; FN3; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 2.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR48016; MAP KINASE KINASE KINASE SSK2-RELATED-RELATED; 1.
DR PANTHER; PTHR48016:SF29; MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 1A; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF00041; fn3; 1.
DR Pfam; PF00069; Pkinase; 2.
DR SMART; SM00060; FN3; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 2.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 2.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:KNC52086.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054408};
KW Transferase {ECO:0000313|EMBL:KNC52086.1}.
FT DOMAIN 7..57
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT DOMAIN 269..366
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 488..752
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 824..1090
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 399..436
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 772..817
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 791..807
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1096 AA; 115439 MW; 313DE406CFADB895 CRC64;
MEASGQGRVD CVRLPVPPSN TTVSGVHFKI WYEDRVRSFF VADCGSTNGT WYAEPALAEE
LKDYRFLGDR YEDAGAQCVM ALKPLSSFKA ADTVFVVEDV ILPAGLGLGA TEALDLDATA
SSTGGRAATL PESRPVDTVI QMLRGPLAGA HYVREFPQTY ALGRAPGKPS LHAPGAVPVL
VETDDPHLSR HHLNLRFVTP PDAAEPGTYM VDVLSTTYYC RKLALGRIDA QLDALPWRRL
EPGSSKLLRH DDLVRAGSVI FLVTSHAEVP RKMDPPYLVA SSPSSLFLKW DPPLSPTTLR
GFVLAISDGQ PGTAAEKWRK LYGGPLREFV AQGLKPSSYY WFRIHARNSG GDGPWSKVIR
FLTVASDDDG SAGNLTPTVS LSMASVASPL GQRRIAFGPT TAAAGPHDPE PESDDDATAS
VTMTGPIGGG GGGESSAALD SSTFTLSTIK ATMEPALLSS GSLPASDSGR DAVTLIREAL
ASSDDLSWRV RSVLGVGGQA RVYLAHMEAP VSMPVAVKEY QLAEGDTSGL ADVTHRINAI
LATLDHPNIV RFYGSATRAQ ADAAVTVVHV FLEYVAGGSL SRMLADLKSG LSEPDAAHYL
GQMVAGVAYL HRHSVIHGDL KPDNVLLKVD GHRTVVKLAD FGGASLLSGA DHTSAFVGTP
HFMAPEAIRT ETATPESDVW SLGCTLLEML TGRMPWSHLN KQAAIFSIGT TLSGPSRPES
LSHPASLFLD ACFALDPAAR ASATDLLDHP FVLGGGDAAE CGDATNASAR RVSSTAAAPV
ADVARSSGSP PHAGSRRSSS RSPMRASHGR GSPSGGASDV VAFEELNVLA AHGESEFVCE
CQDGTEVVVR FLGQSASAET LARVEAMASM RHPNCILFRG SCTRLVAGTV ATGYMVEYMS
STLASLVAEP DFGSSCPLLA KLLLVKNIAS GLYYLHAQNV THGALVPWNV LYDPRSRSCK
VGELGRVSPF YLGSQPDAVC GSLHLYLAPE VALFDALTPS ADVFSLGAIL MLVVFGLAPY
TGLDASEPGG AHTSSPPHTA LLTLASDAGI ATAWSDIQRA CCELVADCLA LKASARPPIE
EVVRKLKALV AQGYAS
//
