ID A0A0L0DLH7_THETB Unreviewed; 2531 AA.
AC A0A0L0DLH7;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=AAA+ ATPase domain-containing protein {ECO:0000259|SMART:SM00382};
GN ORFNames=AMSG_12258 {ECO:0000313|EMBL:KNC53090.1};
OS Thecamonas trahens ATCC 50062.
OC Eukaryota; Apusozoa; Apusomonadida; Apusomonadidae; Thecamonas.
OX NCBI_TaxID=461836 {ECO:0000313|EMBL:KNC53090.1, ECO:0000313|Proteomes:UP000054408};
RN [1] {ECO:0000313|EMBL:KNC53090.1, ECO:0000313|Proteomes:UP000054408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50062 {ECO:0000313|EMBL:KNC53090.1,
RC ECO:0000313|Proteomes:UP000054408};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA Borenstein D., Chapman S., Chen Z., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D.,
RA Larson L., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA Burger G., Gray M.W., Holland P.W.H., King N., Lang F.B.F., Roger A.J.,
RA Ruiz-Trillo I., Lander E., Nusbaum C.;
RT "The Genome Sequence of Thecamonas trahens ATCC 50062.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AAA ATPase family.
CC {ECO:0000256|ARBA:ARBA00006914}.
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DR EMBL; GL349478; KNC53090.1; -; Genomic_DNA.
DR RefSeq; XP_013754806.1; XM_013899352.1.
DR STRING; 461836.A0A0L0DLH7; -.
DR EnsemblProtists; KNC53090; KNC53090; AMSG_12258.
DR GeneID; 25570172; -.
DR eggNOG; KOG0730; Eukaryota.
DR OrthoDB; 5488537at2759; -.
DR Proteomes; UP000054408; Unassembled WGS sequence.
DR GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd19481; RecA-like_protease; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR23073; 26S PROTEASOME REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR23073:SF64; AAA+ ATPASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00004; AAA; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000054408}.
FT DOMAIN 2054..2181
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 2316..2448
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 56..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 105..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 159..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 772..807
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 58..79
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 107..123
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 211..240
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 792..807
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2531 AA; 264076 MW; 3DD6726C5055DFDB CRC64;
MATAVAHGFV PASYSASSSS GDGTTSATVA RFAHKTAPRP HEVVFAVAAA SPVSDSGAGG
EACSSSASPT HGASAKQQCH ELLSQLPKRQ QLAAVALLRR RPGFGSSQIG GEQSSSGSAE
DESLLRRTAS APSALVKRVD VSSELDLIPV PASLPHVLEQ TLPPGSGKRS PRAASTKAAA
TDVVAMDMSH APAPQRRTAS PLHVSPPPER ISGLTISTSS SGSDSESGVG AVTTLSRPSP
TLRKRKSRRS PNGGEKRRKT SHPAPAPLVA AVLPAALSIS GADPFRPWRP VPATLLAAPL
RAPLAVLRQL ARADVVALFH SSPPSSRAVQ IGLVLHLRDV VLPSLGAALG RLPVPSRLAA
VQHLLDTVPL PVHWPTPVSL PHVAAILVWG TAIETLAGDV TFVMDTALPA ILVPLRAALP
SGMPILQHPL SGLAAAAFAA SPAPLDAVTG PHSGPLLSSL ELLGWIQPLL PKLVHPWRLL
VPHIANRLDS LGPRALDEML AWVEALVAPV GKWDPPPSDF LTSVWEAFRA APSSAWLTLG
PPTLSVCVAG SGLSIAGEAR EAPIGRLLHL MACALSSPFA ADTHPRHELS EWDAKRLAST
IIVGLDANLE LATGLDQAMA AAQLSLAVVL ASAVPCETVN SILSRVSALI SPASASNSAH
GLALSALVVF GRVLQSRGMR LEPVMPAIAD RLEAVIGAGA PVPIVTGYLQ AAASLIDTAA
RRDPVTLLGE HLLMSPHIVG LLAPSAPADL WVPAITFLIH MVSLVPPPLP RPPASHDVGR
DGGGSEVEAG SQCPADNESQ DLFPESQMSS ASASASLSFD MGDFDDVDAL VNAHVAEQES
ASTATALLDQ AEVTLLRISA RDLLMAVYAE LCAKSTVAHV HSVQSFLVAT AALRAVTRLM
GVLSEAVSRD GRSAVSAVVS SLGTQSPWLV RDGDALARLV PVGFWTAFLH HGARTPASLV
SPIATELIHA LLLAAVDPFA VDLPRLFHTL ASLPSTAALM GGRAKAAELW AKFSFAGAGE
LEHADEDAVV AIDPATVVLP WQAEPAAWTL PRLQLVKAVV SSVVAGASSP GECLAMVPDV
CARALSELCS RGTTPGPVAR AYEGFALEVM AMLAEQAPLA LADGELWHKT PLYVLLHRFV
IVGSGLEISS GRGKLMAAVM GGIGKLIGAG AAHASRALHE WTARQFDVLP SERAAAQADS
YLLPAVAAAS ARGGSELDTF NNALVDFVVG RHWSGRNVST SRMRRLQLWM AEVIVANPRT
APGFVASCAA RVVGPLLAGA RHRPCASLYV RVLPATLAVV KAMIKTLSGP TLSVLTPVLA
AAAEVVSRVL FDVGDKTLDQ VLAVLHTTVT DEILGDMAAL EAESLASLPQ REGVDPAGGR
GPVRPVMLLR SERGHAAAAA PSFLTRATSL VAEALGVIVA WRKVSSRYRP CKQWLSVAVK
TADALFAPSS RPGAHPVLAA ARLEWQAVRA ALSMDAMEIA VATAQPLVPL SLEAVNGAEV
GSGGSEETMA ALQTTTILAA LAQRTAAASA VRLVGARGMS MAALAEESKG AMAVAAALDE
VRAQVARAHL PVASGDGCGG WCLVHGDGVS AGGVKEQPLF HLLAEGYGWD CREASMFAAV
MVLSMTSAVE ELGFRAPAFY GDHSGGYVLQ AEAAMRLAGA SPRALATFLD PGRAHMKDGL
IQVDASRLPS STLWVSSEFL LALHGVTLGT DASLKLASTK LGELTGHDAL TRNPGRAMGG
VSSGADDDET ALLAELDGLS DDGFDPDALV AQALADAGVT MSSPGARGAG GEGDDGGLAA
YTTDLEYLVD EFEVVYLRMQ ACDNARQVRS ADDVNEMRMF QRGATSSLAA RTRELETKLQ
VAEQKIQVRA AAAEAAGFVP RLEVLARSSG LSAFEKFVLV ACAAFHTYEP IRERSASIRS
SRMMLMGGAF QVSTLLSLYC STLEEQVGQR SAFLKNAPLR ADGYINVVST RGASDLVDCE
VSIDRRVLDH IIGLATPLSE VVEGTHLYTP KVTFDDVVLP VKTRKALMDT LGSYEQLCAL
KASLGLEELV TYGSGMVLLF HGQSGTGKTL TANCVAAHLK RKVLLVNFAS LAETTASVGS
ASDAVKQVFA EAKMHDAIVL FDECESLFMT RARGKNANLP ALLTLMESFE GVSILATNMV
NELDEATFRR VQLSISFSLP DHVLRAAIWR RHVPEGMTLA NDVDVDALAL KFELPGGFIK
NAIVGALSNA LARARAEGGS DGNGELVLTA ADFEAGAQAQ LESMLRQNAF ERRVLPKAGL
DSLVLPEATS AVMGEIVAAQ KAGRILTTQW GFEAATATVA LFHGPPGTGK TMAAAAIGYE
TGRALRVVNC AELVSKYVGE TAKNIEKVFS DAASASTILV FDEAEGLFAA RTAGASATDR
YANVDTGLLL YHLEKFDGMA ILTSNNIEAL DPAFLRRIRY VVKFELPSAS LRAQLWRSSL
PETAPLAADV DFAALGAKYE LAGGDIRNAA WRAACTAAGS GAGAISMAHL DDAGERVSAV
GESSVPEYMY M
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