ID A0A0L0DMW8_THETB Unreviewed; 850 AA.
AC A0A0L0DMW8;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Chromatin-remodelling complex ATPase ISWI2 {ECO:0000313|EMBL:KNC53652.1};
GN ORFNames=AMSG_01361 {ECO:0000313|EMBL:KNC53652.1};
OS Thecamonas trahens ATCC 50062.
OC Eukaryota; Apusozoa; Apusomonadida; Apusomonadidae; Thecamonas.
OX NCBI_TaxID=461836 {ECO:0000313|EMBL:KNC53652.1, ECO:0000313|Proteomes:UP000054408};
RN [1] {ECO:0000313|EMBL:KNC53652.1, ECO:0000313|Proteomes:UP000054408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50062 {ECO:0000313|EMBL:KNC53652.1,
RC ECO:0000313|Proteomes:UP000054408};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA Borenstein D., Chapman S., Chen Z., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D.,
RA Larson L., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA Burger G., Gray M.W., Holland P.W.H., King N., Lang F.B.F., Roger A.J.,
RA Ruiz-Trillo I., Lander E., Nusbaum C.;
RT "The Genome Sequence of Thecamonas trahens ATCC 50062.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
CC {ECO:0000256|ARBA:ARBA00009687}.
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DR EMBL; GL349437; KNC53652.1; -; Genomic_DNA.
DR RefSeq; XP_013761967.1; XM_013906513.1.
DR AlphaFoldDB; A0A0L0DMW8; -.
DR STRING; 461836.A0A0L0DMW8; -.
DR EnsemblProtists; KNC53652; KNC53652; AMSG_01361.
DR GeneID; 25561114; -.
DR eggNOG; KOG0385; Eukaryota.
DR OMA; TAFYRKE; -.
DR OrthoDB; 5482994at2759; -.
DR Proteomes; UP000054408; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0031491; F:nucleosome binding; IEA:InterPro.
DR CDD; cd00167; SANT; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR Gene3D; 1.10.1040.30; ISWI, HAND domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR015194; ISWI_HAND-dom.
DR InterPro; IPR036306; ISWI_HAND-dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR017884; SANT_dom.
DR InterPro; IPR015195; SLIDE.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR45623; CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED; 1.
DR PANTHER; PTHR45623:SF49; SWI_SNF RELATED, MATRIX ASSOCIATED, ACTIN DEPENDENT REGULATOR OF CHROMATIN, SUBFAMILY A, MEMBER 1; 1.
DR Pfam; PF09110; HAND; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF09111; SLIDE; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF101224; HAND domain of the nucleosome remodeling ATPase ISWI; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51293; SANT; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054408}.
FT DOMAIN 1..113
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 244..400
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 613..665
FT /note="SANT"
FT /evidence="ECO:0000259|PROSITE:PS51293"
FT REGION 783..850
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 793..817
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 850 AA; 98006 MW; ED4720D492EF4864 CRC64;
MNEFKRWCPS LRVFKLYGAK HERGLLVEKQ LLPGHFDVCV TSYEMVNIER AAFSKFEWEY
IAIDEAHRIK NESSRLSLNV RAFSSAHRLL ITGTPLQNNV HELWALLNFL LPDVFQSASS
FDEWFDLSSE SAEADAVDQL HKVLRPFLLR RLKADVESSL LPKKELLMKV KLTPMQKEWY
RKLLSRDIDA LNSTTKATSK TRLLNIIMQL RKCCNHPYLF EGAEPGPPYT TDYHLVKNSG
KMLLLDKLLQ VLLARDSRAL IFSQFTRLLD ILEDYLHWRG YEYCRIDGST NGDLRDEQIE
DFNKPGSSKF VFLLSTRAGG LGINLATADT VIIFDSDWNP QMDLQAMDRA HRIGQKKQVI
VARFCADNTI EEKIIERAMQ KLKLDAKIIQ QGRLQPKSKG LSKDEMHSLV RYGADYQFNS
GDADEITEAD IDAALAAGET NAQELSDKVV ELGAPGSTDG FKMESSFATN VFEGVDYTAQ
AASNLRSDFG GHTFINLGKR RRERTSYNIN EYYRETMRSS EATTEKKKKA PRPPKQPFVA
EYQFYPDELH ELLARELWAW RFENTPKYVD EVIANDEELK TDEDRAARRE ELREIAVPLT
EEEMARRDEL LTKGFDNWSR VDFARFYHGC ESYGRESYAD IARVIETKTE DEVREYAKVF
FERGPDHLSS WPKVIDVIEK GEEKLRRHST KIKLIRQAVA EAPGNPYHSL EIKTKSSMYT
AAEDRFIICK INDLGYGEWD KLKLAIRSAW EFRFDWYFKS RTPIELNRRC DALLRAYEKS
KGGSSLAPAR RRSSKSKASK SKASKSKASK SSKRKRSSTK SQPNSDDEYD NEEDEEEEVV
ASRSRKRSKR
//
