ID A0A0L0DN26_THETB Unreviewed; 682 AA.
AC A0A0L0DN26;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=AMSG_08958 {ECO:0000313|EMBL:KNC52818.1};
OS Thecamonas trahens ATCC 50062.
OC Eukaryota; Apusozoa; Apusomonadida; Apusomonadidae; Thecamonas.
OX NCBI_TaxID=461836 {ECO:0000313|EMBL:KNC52818.1, ECO:0000313|Proteomes:UP000054408};
RN [1] {ECO:0000313|EMBL:KNC52818.1, ECO:0000313|Proteomes:UP000054408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50062 {ECO:0000313|EMBL:KNC52818.1,
RC ECO:0000313|Proteomes:UP000054408};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA Borenstein D., Chapman S., Chen Z., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D.,
RA Larson L., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA Burger G., Gray M.W., Holland P.W.H., King N., Lang F.B.F., Roger A.J.,
RA Ruiz-Trillo I., Lander E., Nusbaum C.;
RT "The Genome Sequence of Thecamonas trahens ATCC 50062.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL349476; KNC52818.1; -; Genomic_DNA.
DR RefSeq; XP_013754924.1; XM_013899470.1.
DR AlphaFoldDB; A0A0L0DN26; -.
DR STRING; 461836.A0A0L0DN26; -.
DR EnsemblProtists; KNC52818; KNC52818; AMSG_08958.
DR GeneID; 25567532; -.
DR eggNOG; KOG0341; Eukaryota.
DR OMA; LGDERGC; -.
DR OrthoDB; 5487240at2759; -.
DR Proteomes; UP000054408; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR CDD; cd18787; SF2_C_DEAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR PANTHER; PTHR47958; ATP-DEPENDENT RNA HELICASE DBP3; 1.
DR PANTHER; PTHR47958:SF103; ATP-DEPENDENT RNA HELICASE DDX41-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51195; Q_MOTIF; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054408}.
FT DOMAIN 244..272
FT /note="DEAD-box RNA helicase Q"
FT /evidence="ECO:0000259|PROSITE:PS51195"
FT DOMAIN 275..460
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 489..633
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 244..272
FT /note="Q motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00552"
FT COMPBIAS 1..17
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 85..101
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 682 AA; 72217 MW; 604F25705020F519 CRC64;
MGTAATRKRK RRRSGSRLGS GSRSGSGSGS GSGLGKRRKR AKTKAKEEED EEEEAGREGV
TESGKGRHGG GNAVTGGETG TGAPPAGTES GSGSGSSSLA EFRSRAKGGH GDSRQSGGRG
VADAGADVGS GGGGGGSGGM LSAGGKQLSL LEETVHLRRA GKLKELTKEE LEAEEERKLV
EAFASTKALV SAAELAEGGR TVQPLPTTWR PPRWAQERGP EVYEALRTKY NIEIKGEDVP
KCLTTFEAMK LPPAIVKHLV GKSILKPTPI QMQGLPTILS GRDMIGISYT GSGKTLVFTL
PLVLVALEEE LRMPLMPGEG PVGVVLSPSR ELARQTHQIA CDLAAALHAD GGPKLRMALC
MGGVPVKPAL EMVDEGVHAV VATPGRLLDM LKKEQFSLRL VRYMCLDEAD RLISDGFEED
MRDILSFTGK APRQTVLFSA TMAQSIKEFG ATALVSPVVV TVGRAGAASL DIIIEVEYVA
TEEEKMSYVV NSVLDKTEPP VIVFSSSSSV VDALLEYMMI KGVAATAIHG GLSQSERLQA
MDDFKNGKAD VLIASDVAAK GIDFPHIAHV ICVDLPKEFE MLPHRLGRTG RAGNVGVASV
LITPRDDPIM LSDLRAMLIE AKQRVPPYLL RDATASASAT EACPMCGGLG HRIADCPLVT
QRARTNARSR MRRGDEHRVG DY
//
