ID A0A0L0DNC8_THETB Unreviewed; 742 AA.
AC A0A0L0DNC8;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Catalase-peroxidase {ECO:0000256|RuleBase:RU003451};
DE EC=1.11.1.21 {ECO:0000256|RuleBase:RU003451};
GN ORFNames=AMSG_09476 {ECO:0000313|EMBL:KNC53760.1};
OS Thecamonas trahens ATCC 50062.
OC Eukaryota; Apusozoa; Apusomonadida; Apusomonadidae; Thecamonas.
OX NCBI_TaxID=461836 {ECO:0000313|EMBL:KNC53760.1, ECO:0000313|Proteomes:UP000054408};
RN [1] {ECO:0000313|EMBL:KNC53760.1, ECO:0000313|Proteomes:UP000054408}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50062 {ECO:0000313|EMBL:KNC53760.1,
RC ECO:0000313|Proteomes:UP000054408};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA Borenstein D., Chapman S., Chen Z., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E., Heiman D., Hepburn T., Howarth C., Jen D.,
RA Larson L., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Thomson T., Walk T., White J., Yandava C.,
RA Burger G., Gray M.W., Holland P.W.H., King N., Lang F.B.F., Roger A.J.,
RA Ruiz-Trillo I., Lander E., Nusbaum C.;
RT "The Genome Sequence of Thecamonas trahens ATCC 50062.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2 H2O2 = 2 H2O + O2; Xref=Rhea:RHEA:20309, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15379, ChEBI:CHEBI:16240; EC=1.11.1.21;
CC Evidence={ECO:0000256|ARBA:ARBA00001378,
CC ECO:0000256|RuleBase:RU003451};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=AH2 + H2O2 = A + 2 H2O; Xref=Rhea:RHEA:30275,
CC ChEBI:CHEBI:13193, ChEBI:CHEBI:15377, ChEBI:CHEBI:16240,
CC ChEBI:CHEBI:17499; EC=1.11.1.21;
CC Evidence={ECO:0000256|RuleBase:RU003451};
CC -!- COFACTOR:
CC Name=heme b; Xref=ChEBI:CHEBI:60344;
CC Evidence={ECO:0000256|ARBA:ARBA00001970,
CC ECO:0000256|RuleBase:RU003451};
CC -!- SIMILARITY: Belongs to the peroxidase family. Peroxidase/catalase
CC subfamily. {ECO:0000256|RuleBase:RU003451}.
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DR EMBL; GL349482; KNC53760.1; -; Genomic_DNA.
DR RefSeq; XP_013754323.1; XM_013898869.1.
DR AlphaFoldDB; A0A0L0DNC8; -.
DR STRING; 461836.A0A0L0DNC8; -.
DR EnsemblProtists; KNC53760; KNC53760; AMSG_09476.
DR GeneID; 25567931; -.
DR eggNOG; ENOG502QTDY; Eukaryota.
DR OMA; GPETTWL; -.
DR OrthoDB; 317402at2759; -.
DR Proteomes; UP000054408; Unassembled WGS sequence.
DR GO; GO:0004096; F:catalase activity; IEA:InterPro.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR CDD; cd00649; catalase_peroxidase_1; 1.
DR Gene3D; 1.10.520.10; -; 2.
DR Gene3D; 1.10.420.10; Peroxidase, domain 2; 2.
DR HAMAP; MF_01961; Catal_peroxid; 1.
DR InterPro; IPR000763; Catalase_peroxidase.
DR InterPro; IPR002016; Haem_peroxidase.
DR InterPro; IPR010255; Haem_peroxidase_sf.
DR InterPro; IPR019794; Peroxidases_AS.
DR InterPro; IPR019793; Peroxidases_heam-ligand_BS.
DR NCBIfam; TIGR00198; cat_per_HPI; 1.
DR PANTHER; PTHR30555:SF0; CATALASE-PEROXIDASE; 1.
DR PANTHER; PTHR30555; HYDROPEROXIDASE I, BIFUNCTIONAL CATALASE-PEROXIDASE; 1.
DR Pfam; PF00141; peroxidase; 2.
DR PRINTS; PR00460; BPEROXIDASE.
DR PRINTS; PR00458; PEROXIDASE.
DR SUPFAM; SSF48113; Heme-dependent peroxidases; 2.
DR PROSITE; PS00435; PEROXIDASE_1; 1.
DR PROSITE; PS00436; PEROXIDASE_2; 1.
DR PROSITE; PS50873; PEROXIDASE_4; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|RuleBase:RU003451};
KW Hydrogen peroxide {ECO:0000256|ARBA:ARBA00023324,
KW ECO:0000256|RuleBase:RU003451};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU003451};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU003451};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003451};
KW Peroxidase {ECO:0000256|ARBA:ARBA00022559, ECO:0000256|RuleBase:RU003451};
KW Reference proteome {ECO:0000313|Proteomes:UP000054408}.
FT DOMAIN 140..419
FT /note="Plant heme peroxidase family profile"
FT /evidence="ECO:0000259|PROSITE:PS50873"
SQ SEQUENCE 742 AA; 79826 MW; CAD142FB937292A0 CRC64;
MSASSSTGRC PNKSKGGTCP FKGHTNLAVG APGIREWWPN SLNLKPLVTN SGLADPMGED
FDYAAEFAKV NLDELRNDVM KVMTTSQDWW PADYGHYGPF FIRMSWHAAG TYRVSDGRGG
AGTGMQRFAP LNSWPDNANL DKARRLLWPI KKKYGRKISW ADLIVYAGNL AIESMGLETV
GFGFGRIDKY EPEDIFWGAE TEWLTDSERY PKDGKRELAE GLGAVEHGLI YVNPEGPGGE
PDPMKAAADI RESFGRMAMN DEETVALIAG GHTFGKAHGA ADPSKYVGPE PEGESITARG
LGWNSSYKSG AGAHAITSGL EGAWTPTPIQ WDNSYFDMLF GYEWELTKSP AGASQWTPKG
GSGSGLVPDA HDEAKSHPPI MFTTDLALRI DPDYERISRH FHSNPEAFGN AFARAWFKLL
HRDMGPIARY LGPLVPTTPE LWQDPLPSPP AAVIDADDIA TLKAAISASD LTPAQLVRTA
WASASTYRDT DKRGGANGAR IRLSPQKDWP VNDPPALAAV LAVYDGIQAN FNAGAKSVSM
ADLIVLGGVV GVEAAAAAAG HDICVAFTPG RTDASQDQTD TEGFAVLEPT ADAFRNYYAP
DNKRPAEQLL VDKTILLGIT SPEMAVLLAG LRVIGANAAG SDLGVLTDRP GALTTDFFVN
ILDDSIDWAP AADGVYVGTE RGSGATKWSA TRADLIFSSN SQLRALAEVF AADDAADHFV
NSFAAAWAKV MDLDRFDLRS RM
//
