ID A0A0L0FG86_9EUKA Unreviewed; 813 AA.
AC A0A0L0FG86;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=FAD-binding FR-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SARC_12414 {ECO:0000313|EMBL:KNC75053.1};
OS Sphaeroforma arctica JP610.
OC Eukaryota; Ichthyosporea; Ichthyophonida; Sphaeroforma.
OX NCBI_TaxID=667725 {ECO:0000313|EMBL:KNC75053.1, ECO:0000313|Proteomes:UP000054560};
RN [1] {ECO:0000313|EMBL:KNC75053.1, ECO:0000313|Proteomes:UP000054560}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP610 {ECO:0000313|EMBL:KNC75053.1,
RC ECO:0000313|Proteomes:UP000054560};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Young S.K., Zeng Q., Gargeya S., Alvarado L., Berlin A.,
RA Chapman S.B., Chen Z., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E., Heiman D., Howarth C., Mehta T., Neiman D.,
RA Pearson M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C.,
RA Sykes S., White J., Yandava C., Burger G., Gray M.W., Holland P.W.H.,
RA King N., Lang F.B.F., Roger A.J., Ruiz-Trillo I., Haas B., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Sphaeroforma arctica JP610.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KQ243884; KNC75053.1; -; Genomic_DNA.
DR RefSeq; XP_014148955.1; XM_014293480.1.
DR AlphaFoldDB; A0A0L0FG86; -.
DR STRING; 667725.A0A0L0FG86; -.
DR EnsemblProtists; KNC75053; KNC75053; SARC_12414.
DR GeneID; 25912918; -.
DR eggNOG; KOG0039; Eukaryota.
DR OrthoDB; 2671609at2759; -.
DR Proteomes; UP000054560; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd06186; NOX_Duox_like_FAD_NADP; 1.
DR Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR InterPro; IPR013112; FAD-bd_8.
DR InterPro; IPR013130; Fe3_Rdtase_TM_dom.
DR InterPro; IPR013121; Fe_red_NAD-bd_6.
DR InterPro; IPR039261; FNR_nucleotide-bd.
DR PANTHER; PTHR11972; NADPH OXIDASE; 1.
DR Pfam; PF08022; FAD_binding_8; 1.
DR Pfam; PF01794; Ferric_reduct; 1.
DR Pfam; PF08030; NAD_binding_6; 1.
DR SFLD; SFLDS00052; Ferric_Reductase_Domain; 1.
DR SFLD; SFLDG01168; Ferric_reductase_subgroup_(FRE; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000054560};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 35..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 124..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..271
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..312
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 338..360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 381..402
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 422..442
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 449..468
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 346..464
FT /note="Ferric oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01794"
FT DOMAIN 500..577
FT /note="FAD-binding 8"
FT /evidence="ECO:0000259|Pfam:PF08022"
FT DOMAIN 595..795
FT /note="Ferric reductase NAD binding"
FT /evidence="ECO:0000259|Pfam:PF08030"
SQ SEQUENCE 813 AA; 92444 MW; C69C56B8E3A84905 CRC64;
MIHLNSIWKV DTGISSDHIQ PDVISKNVEG LPKKVVMSWI VTVALVLISA IGFAIFAESP
CMLADSTECE EAEESMSYWQ LMMSGVENIP LIGLVVYTFA FPCVCITLMY ALRFTLVLCS
PRNQTMVAVG LALIAISLGT AAFLVWGDVW NETKEGFIVA NAWGMFALSI CLAATLMMIA
CRRLVSKWQR PIPSWTISIA FTFFFIPLCF LITVLFPQAK WNVANGFIRS KDVKTNDGWS
FGPEDYKFSI YTEVLVLYLT IFTTCLAMAL AKEYRASRLI LKRALRLRSF RTTLGSSIAV
LVYLALNVGW TYRFSVDSTS GKTVTKCYDT DMCSKINAVA HVAANLANLQ ISLLTLPIGR
TNVFGKIMGV SWEASIKWHR FTGYLFLLFS TIHGALWMVQ WAMRSDFTGT PEYMKKDLTN
PMIFLVQCVM LVVFGVLTLP FFRRRFYEWF FVSHHFYVVV FVTVVWHAGR LWQLLLPAIG
LVVIDQAIRL YRCTRDVGQS KITVYGDKFV RLDVSDLQGK TIGFTTMQFA YINIPAISTT
QWHPITIGSS PAEDRITFYI KSLGHWSSSL TKLGGESPLV HLDFGYGTPP VFNDFENITF
VCGGVGFTAC MGFMRSLIYE PELYPNVKRV QIILSMREKT VLRMAEDTLT LLMNNKNDVA
STVQIFLTGQ GPEEPEDELD EHIFSRTKFS STEFDHEMKE EKPPQKPEFD FEMNEEKLPQ
KPEFDFEMNE EKLPQKPEFD FEMNEEKLPQ KSEIQKVNDF DQNNWSIEQG RPNLENIIFG
DLVLACGTQK LIESARIVAD NKGAVFHKER FIF
//
