ID A0A0L0FKX7_9EUKA Unreviewed; 377 AA.
AC A0A0L0FKX7;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Cyclic nucleotide-binding domain-containing protein {ECO:0000259|PROSITE:PS50042};
GN ORFNames=SARC_10094 {ECO:0000313|EMBL:KNC77442.1};
OS Sphaeroforma arctica JP610.
OC Eukaryota; Ichthyosporea; Ichthyophonida; Sphaeroforma.
OX NCBI_TaxID=667725 {ECO:0000313|EMBL:KNC77442.1, ECO:0000313|Proteomes:UP000054560};
RN [1] {ECO:0000313|EMBL:KNC77442.1, ECO:0000313|Proteomes:UP000054560}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP610 {ECO:0000313|EMBL:KNC77442.1,
RC ECO:0000313|Proteomes:UP000054560};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Young S.K., Zeng Q., Gargeya S., Alvarado L., Berlin A.,
RA Chapman S.B., Chen Z., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E., Heiman D., Howarth C., Mehta T., Neiman D.,
RA Pearson M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C.,
RA Sykes S., White J., Yandava C., Burger G., Gray M.W., Holland P.W.H.,
RA King N., Lang F.B.F., Roger A.J., Ruiz-Trillo I., Haas B., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Sphaeroforma arctica JP610.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell junction, tight junction
CC {ECO:0000256|ARBA:ARBA00004435}. Cell membrane
CC {ECO:0000256|ARBA:ARBA00004236}. Lateral cell membrane
CC {ECO:0000256|ARBA:ARBA00004124}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the popeye family.
CC {ECO:0000256|ARBA:ARBA00007146}.
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DR EMBL; KQ242731; KNC77442.1; -; Genomic_DNA.
DR RefSeq; XP_014151344.1; XM_014295869.1.
DR AlphaFoldDB; A0A0L0FKX7; -.
DR EnsemblProtists; KNC77442; KNC77442; SARC_10094.
DR GeneID; 25910598; -.
DR eggNOG; ENOG502SD0D; Eukaryota.
DR Proteomes; UP000054560; Unassembled WGS sequence.
DR GO; GO:0005923; C:bicellular tight junction; IEA:UniProtKB-SubCell.
DR GO; GO:0016328; C:lateral plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR006916; Popeye_prot.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR12101:SF17; BLOOD VESSEL EPICARDIAL SUBSTANCE; 1.
DR PANTHER; PTHR12101; POPEYE DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF04831; Popeye; 1.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Cell junction {ECO:0000256|ARBA:ARBA00022949};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00022475};
KW Reference proteome {ECO:0000313|Proteomes:UP000054560};
KW Tight junction {ECO:0000256|ARBA:ARBA00022427}.
FT DOMAIN 204..321
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 327..358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 331..358
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 377 AA; 42518 MW; E5D3CA9F4D6AA069 CRC64;
MTSYLETQAT SSVSRIRTPT QRHAHAQMRT HTRIMRPEVM RSKHRITRDV GGIGGSWSAS
RNNARMAEEG VRTALHSRPK MTSGDEALQM NVVQKWYHTH LGDGRAGPLV SEKASNRMIN
GSAIVSAFGY AMTDIASLRA LQLVSASMRV TNLAISYPKP LFLQMRWSLL FITINLVNIV
KLYLESQSVD FSTAERELYE RHFMPKGVSE RACRRLFDHG EWMTVESGQT LLQEGVVHNN
LYLIYKGTLD VSVDEQVVGY LNDGSWMGEM VFLDSSQDKA SATCTTSGPV MVLRWEIDDL
RNFLSTQKQV KSQLTLAIAE SSMSKIRQTS QKFGQEHKRH QKPEKQQEKN SKVTEGEETV
ITIKVHVEPE NLTGNAN
//
