ID A0A0L0G621_9EUKA Unreviewed; 496 AA.
AC A0A0L0G621;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Citrate synthase {ECO:0000256|RuleBase:RU000441};
GN ORFNames=SARC_04091 {ECO:0000313|EMBL:KNC83658.1};
OS Sphaeroforma arctica JP610.
OC Eukaryota; Ichthyosporea; Ichthyophonida; Sphaeroforma.
OX NCBI_TaxID=667725 {ECO:0000313|EMBL:KNC83658.1, ECO:0000313|Proteomes:UP000054560};
RN [1] {ECO:0000313|EMBL:KNC83658.1, ECO:0000313|Proteomes:UP000054560}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP610 {ECO:0000313|EMBL:KNC83658.1,
RC ECO:0000313|Proteomes:UP000054560};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Young S.K., Zeng Q., Gargeya S., Alvarado L., Berlin A.,
RA Chapman S.B., Chen Z., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E., Heiman D., Howarth C., Mehta T., Neiman D.,
RA Pearson M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C.,
RA Sykes S., White J., Yandava C., Burger G., Gray M.W., Holland P.W.H.,
RA King N., Lang F.B.F., Roger A.J., Ruiz-Trillo I., Haas B., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Sphaeroforma arctica JP610.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the citrate synthase family.
CC {ECO:0000256|ARBA:ARBA00010566, ECO:0000256|RuleBase:RU000441}.
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DR EMBL; KQ241817; KNC83658.1; -; Genomic_DNA.
DR RefSeq; XP_014157560.1; XM_014302085.1.
DR AlphaFoldDB; A0A0L0G621; -.
DR STRING; 667725.A0A0L0G621; -.
DR EnsemblProtists; KNC83658; KNC83658; SARC_04091.
DR GeneID; 25904595; -.
DR eggNOG; KOG2617; Eukaryota.
DR OrthoDB; 3513214at2759; -.
DR Proteomes; UP000054560; Unassembled WGS sequence.
DR GO; GO:0004108; F:citrate (Si)-synthase activity; IEA:InterPro.
DR GO; GO:0006101; P:citrate metabolic process; IEA:InterPro.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR Gene3D; 1.10.580.10; Citrate Synthase, domain 1; 1.
DR Gene3D; 1.10.230.10; Cytochrome P450-Terp, domain 2; 1.
DR InterPro; IPR016142; Citrate_synth-like_lrg_a-sub.
DR InterPro; IPR016143; Citrate_synth-like_sm_a-sub.
DR InterPro; IPR002020; Citrate_synthase.
DR InterPro; IPR019810; Citrate_synthase_AS.
DR InterPro; IPR010109; Citrate_synthase_euk.
DR InterPro; IPR036969; Citrate_synthase_sf.
DR NCBIfam; TIGR01793; cit_synth_euk; 1.
DR PANTHER; PTHR11739; CITRATE SYNTHASE; 1.
DR PANTHER; PTHR11739:SF8; CITRATE SYNTHASE, MITOCHONDRIAL; 1.
DR Pfam; PF00285; Citrate_synt; 1.
DR PRINTS; PR00143; CITRTSNTHASE.
DR SUPFAM; SSF48256; Citrate synthase; 1.
DR PROSITE; PS00480; CITRATE_SYNTHASE; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000054560};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU000441}.
FT ACT_SITE 313
FT /evidence="ECO:0000256|PIRSR:PIRSR610109-1"
FT ACT_SITE 365
FT /evidence="ECO:0000256|PIRSR:PIRSR610109-1"
FT ACT_SITE 420
FT /evidence="ECO:0000256|PIRSR:PIRSR610109-1"
SQ SEQUENCE 496 AA; 54615 MW; 68DB310636129E96 CRC64;
MSLAFTATRA LRASKWQSTL RTAAAAVVTR QGLRNYSSSN GLEPLYDRLH EILPKHAQDV
KEFRAAHGGD TLGILTVDMA YGGMRGIKGM VTETSVLDAD EGIRYQGHTL MELQETLPRG
PGGQEPLAEG ALWLLLTGEL PTQEQTTLLS KELARRAELP HHVVQMINNF PAELHPMAQL
SAATTALHSE SKFAKAYASG VPKSKYWELT LEDSIDLIAK LPVIASMIYR NVFHDGRTVG
TIDPDKDMGA NFASMLGFSD EGFIDLLRLY LVIHADHEGG NVSAHTTHLV GSALSDPYLA
YGAALNGLAG PLHGLANQEV LSWLTKFKTR LGEGDDWHAN LTKQRISDEV WNTLNSGQVI
PGYGHAVLRK TDPRYTCQRD FALKHLPDSD DFKLVSMLYE VVPDILLEHG KSKNPWPNVD
AHSGILLQHY GLTEMNFYTV LFGVSRAIGV LPSLVWSRSM GLPLERPKSM STPGLKAFVA
AARSELKEKQ QRSKYV
//
