ID A0A0L0G8L4_9EUKA Unreviewed; 448 AA.
AC A0A0L0G8L4;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Peptidase A1 domain-containing protein {ECO:0000259|PROSITE:PS51767};
GN ORFNames=SARC_02472 {ECO:0000313|EMBL:KNC85350.1};
OS Sphaeroforma arctica JP610.
OC Eukaryota; Ichthyosporea; Ichthyophonida; Sphaeroforma.
OX NCBI_TaxID=667725 {ECO:0000313|EMBL:KNC85350.1, ECO:0000313|Proteomes:UP000054560};
RN [1] {ECO:0000313|EMBL:KNC85350.1, ECO:0000313|Proteomes:UP000054560}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP610 {ECO:0000313|EMBL:KNC85350.1,
RC ECO:0000313|Proteomes:UP000054560};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Young S.K., Zeng Q., Gargeya S., Alvarado L., Berlin A.,
RA Chapman S.B., Chen Z., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E., Heiman D., Howarth C., Mehta T., Neiman D.,
RA Pearson M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C.,
RA Sykes S., White J., Yandava C., Burger G., Gray M.W., Holland P.W.H.,
RA King N., Lang F.B.F., Roger A.J., Ruiz-Trillo I., Haas B., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Sphaeroforma arctica JP610.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase A1 family.
CC {ECO:0000256|ARBA:ARBA00007447}.
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DR EMBL; KQ241707; KNC85350.1; -; Genomic_DNA.
DR RefSeq; XP_014159252.1; XM_014303777.1.
DR AlphaFoldDB; A0A0L0G8L4; -.
DR STRING; 667725.A0A0L0G8L4; -.
DR EnsemblProtists; KNC85350; KNC85350; SARC_02472.
DR GeneID; 25902976; -.
DR eggNOG; KOG1339; Eukaryota.
DR OrthoDB; 2900143at2759; -.
DR Proteomes; UP000054560; Unassembled WGS sequence.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd05471; pepsin_like; 1.
DR Gene3D; 2.40.70.10; Acid Proteases; 2.
DR InterPro; IPR001461; Aspartic_peptidase_A1.
DR InterPro; IPR034164; Pepsin-like_dom.
DR InterPro; IPR033121; PEPTIDASE_A1.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR PANTHER; PTHR47965; ASPARTYL PROTEASE-RELATED; 1.
DR PANTHER; PTHR47965:SF12; PEPTIDASE A1 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00026; Asp; 1.
DR PRINTS; PR00792; PEPSIN.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR PROSITE; PS51767; PEPTIDASE_A1; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR601461-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000054560};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..448
FT /note="Peptidase A1 domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5005539175"
FT DOMAIN 64..410
FT /note="Peptidase A1"
FT /evidence="ECO:0000259|PROSITE:PS51767"
FT ACT_SITE 80
FT /evidence="ECO:0000256|PIRSR:PIRSR601461-1"
FT ACT_SITE 286
FT /evidence="ECO:0000256|PIRSR:PIRSR601461-1"
FT DISULFID 93..116
FT /evidence="ECO:0000256|PIRSR:PIRSR601461-2"
SQ SEQUENCE 448 AA; 47341 MW; D74A3B3010D4E83A CRC64;
MKIFEIPALV TAVGALLLTI SCDAQMIEMP MVRVPNIVNR NRRQTTQPMF ENPMGGGVSE
FLAYAANFTI GGASFYFLVD SGSADLLVTA VGCTNHRTGD CTGPDFEPIS PSLGQCTATS
YYENTGTATS HLGEVDCYGT ADSATYLQYD VYTDAVVFSN ATAVTQALGS ITASTPDFFI
APQVAGIIGM AYPGQSTIYG LNKDYTPYLN TLTNEKVIST AAFAMCFNGQ VDGGPAGGLL
VLGGGIISGL TYVDVVNQWW YAVALSSMTV AGTDVGLPSE GFTIVDSGTS GLVLTDTMYT
AFNTALCTFA EENGINGLCV DNSVESTVQL TTDELASLPP VLVSLADNYV YSINSSSYLK
SQGGNSYLYL IQQSGVENGQ KDSASVILGD VYLQGQWVYF DQQNNRLGLA AVSNCNQNYT
SSALSIHTPS KPVVALSATL VAIITWLF
//
