ID A0A0L0GFT7_9EUKA Unreviewed; 532 AA.
AC A0A0L0GFT7;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Kazal-like domain-containing protein {ECO:0000259|PROSITE:PS51465};
GN ORFNames=SARC_00215 {ECO:0000313|EMBL:KNC87709.1};
OS Sphaeroforma arctica JP610.
OC Eukaryota; Ichthyosporea; Ichthyophonida; Sphaeroforma.
OX NCBI_TaxID=667725 {ECO:0000313|EMBL:KNC87709.1, ECO:0000313|Proteomes:UP000054560};
RN [1] {ECO:0000313|EMBL:KNC87709.1, ECO:0000313|Proteomes:UP000054560}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JP610 {ECO:0000313|EMBL:KNC87709.1,
RC ECO:0000313|Proteomes:UP000054560};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Young S.K., Zeng Q., Gargeya S., Alvarado L., Berlin A.,
RA Chapman S.B., Chen Z., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E., Heiman D., Howarth C., Mehta T., Neiman D.,
RA Pearson M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C.,
RA Sykes S., White J., Yandava C., Burger G., Gray M.W., Holland P.W.H.,
RA King N., Lang F.B.F., Roger A.J., Ruiz-Trillo I., Haas B., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Sphaeroforma arctica JP610.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KQ241601; KNC87709.1; -; Genomic_DNA.
DR RefSeq; XP_014161611.1; XM_014306136.1.
DR AlphaFoldDB; A0A0L0GFT7; -.
DR STRING; 667725.A0A0L0GFT7; -.
DR EnsemblProtists; KNC87709; KNC87709; SARC_00215.
DR GeneID; 25900719; -.
DR eggNOG; KOG3509; Eukaryota.
DR OrthoDB; 2878621at2759; -.
DR Proteomes; UP000054560; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00104; KAZAL_FS; 5.
DR Gene3D; 3.30.60.30; -; 5.
DR InterPro; IPR002350; Kazal_dom.
DR InterPro; IPR036058; Kazal_dom_sf.
DR PANTHER; PTHR10913:SF45; AGRIN; 1.
DR PANTHER; PTHR10913; FOLLISTATIN-RELATED; 1.
DR Pfam; PF00050; Kazal_1; 3.
DR Pfam; PF07648; Kazal_2; 2.
DR SMART; SM00280; KAZAL; 5.
DR SUPFAM; SSF100895; Kazal-type serine protease inhibitors; 5.
DR PROSITE; PS51465; KAZAL_2; 5.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054560};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..532
FT /note="Kazal-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5005539408"
FT TRANSMEM 446..471
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 96..148
FT /note="Kazal-like"
FT /evidence="ECO:0000259|PROSITE:PS51465"
FT DOMAIN 175..227
FT /note="Kazal-like"
FT /evidence="ECO:0000259|PROSITE:PS51465"
FT DOMAIN 249..301
FT /note="Kazal-like"
FT /evidence="ECO:0000259|PROSITE:PS51465"
FT DOMAIN 318..360
FT /note="Kazal-like"
FT /evidence="ECO:0000259|PROSITE:PS51465"
FT DOMAIN 362..416
FT /note="Kazal-like"
FT /evidence="ECO:0000259|PROSITE:PS51465"
FT REGION 417..436
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 509..532
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 420..436
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 532 AA; 57294 MW; 62F2FCC1D48B84C7 CRC64;
MKTTYALLAL STLATLRSVH GVHADHLHEH RHEHEYRDAT ELRDIHDIAD KIKAAVHQAT
DKAKEVSDTI AHQVKEGAPD VEKAVEMTVD DFAKKVKHLI DCPLMCTMDY RPVCASDGNT
YSNKCVMRSK ACEKQEHFTV LYEGECKDTV VTIPVTGTKS ETNENTGNKA DEPIPIIDMD
CFKFCAQSYK PVCGSDGATY SNECELGNAN CISSTKVTVQ SEGVCETILI LNLGPVVPND
EEPEGKSTVD SKESCRRPCP RNLRPVCASN GKTYPNKCVM EVSGCEINEA LTVSHNGPCE
AEVDEGANAK ANEADAETAE KDSCLKPCNR ILIPVCASNG KTYSNVCEME IGACQLNDEL
TVQFPGYCCE LSFCTAEYAP VCATDGNTYS NKCELESAKC GDKSFIELKH EGACGPDSGS
TGAGASSGTS ASHSSGESES SGLSDLFWIC AVAGIILAVV SVGAVLIVIV ARRKQAASSP
LDYSKLFEEQ EGPPAYDFQQ SEILAAAPPS MKFNGNHYEP VPDTDKTDQT KQ
//
