ID A0A0L0H5Y9_SPIPD Unreviewed; 1175 AA.
AC A0A0L0H5Y9;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Rho-GAP domain-containing protein {ECO:0000259|PROSITE:PS50238};
GN ORFNames=SPPG_07755 {ECO:0000313|EMBL:KNC96930.1};
OS Spizellomyces punctatus (strain DAOM BR117).
OC Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC Chytridiomycota incertae sedis; Chytridiomycetes; Spizellomycetales;
OC Spizellomycetaceae; Spizellomyces.
OX NCBI_TaxID=645134 {ECO:0000313|EMBL:KNC96930.1, ECO:0000313|Proteomes:UP000053201};
RN [1] {ECO:0000313|EMBL:KNC96930.1, ECO:0000313|Proteomes:UP000053201}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DAOM BR117 {ECO:0000313|EMBL:KNC96930.1,
RC ECO:0000313|Proteomes:UP000053201};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA Borenstein D., Chapman S., Chen Z., Engels R., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C.,
RA Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A.,
RA Saif S., Shenoy N., Sisk P., Stolte C., Sykes S., Thomson T., Walk T.,
RA White J., Yandava C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Lander E., Nusbaum C.;
RT "The Genome Sequence of Spizellomyces punctatus strain DAOM BR117.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KQ257466; KNC96930.1; -; Genomic_DNA.
DR RefSeq; XP_016604970.1; XM_016755914.1.
DR AlphaFoldDB; A0A0L0H5Y9; -.
DR STRING; 645134.A0A0L0H5Y9; -.
DR GeneID; 27690952; -.
DR VEuPathDB; FungiDB:SPPG_07755; -.
DR eggNOG; ENOG502QQWB; Eukaryota.
DR InParanoid; A0A0L0H5Y9; -.
DR OMA; RKTWIYE; -.
DR OrthoDB; 1328399at2759; -.
DR Proteomes; UP000053201; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR23065; PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1; 1.
DR PANTHER; PTHR23065:SF17; RHO-GTPASE-ACTIVATING PROTEIN RGD2; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00049; DEP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053201}.
FT DOMAIN 491..691
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 57..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 700..726
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 742..930
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 959..994
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1011..1152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 771..800
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 805..841
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 860..922
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1024..1045
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1076..1092
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1093..1115
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1175 AA; 129211 MW; 7C2237F4EA34B032 CRC64;
MLRFEDCFWG TGEDPTLGVR TLHTVFMQHL AEAEDMLALV RARVTMEETY ASNLLELGRH
SGSGSGGTSE KELRRYSRAS TPAIAAGTMT GLAGEKSKLS LNQIAQGLGN AAAMLQSAAV
SSRLSRPTSW NMVAEPESDT STIGPIDDQS SIRPVIRTIR EQNVAMAAIH RRHADTLTLA
VISPLQAFVE QHKRAMTKKK NEVDLNHQQL SRLAADIEAR RTVYLQKCRI AEEEDRKFRE
DGETRARRVS TAPIMIGSRS VGPNEFTTIV EQMRKEVKIK SIMTDLGLFE GCFMGDDAIE
YLRKRYPGVP RGDLRNVCQE ILDRRLITVV VGPNDSDFDR ALPYQFGRPL LKTGEPPHVK
ARKDAEMARL DYDAAIKTAE HTRSALEFHI TDYLIAAQDA EKYRLKVIKE AVLALESAQV
FVVDEVRTTW RPPSLEDAAD PMSPTSLLNS PDPETGVQYI ATRYRTGHLR SKPFVFESYK
TGRAPHQVFG IGFEELFRAT NTAVPPIVRK CVGSLYESFV NGRSAVDTWI TPNPDLPSVQ
FLRMEFNSSP KGGRVSSRTL KRYQPQVVAG VLKLYLVEAP ASLCSYDTYE TLKMLYSDGF
QSFDDDVRIK SVTSLLTTLS PPHFDSLKFF TGYLHELTKD LDDNDDRIIR LAYSLAPCIL
RPKTETPETL QDQHPWRFTL ELMVRYTDFF GPVDKTALME GALEPSPPPS PEPDMDGDDL
ASDIGSPRSV VQGLKVKGLG ELATKGMNSP PATPPLREPS TPKGTGSWFP WPLSGNATSN
GSGPSSPLTG APQTPTGAES PDSDKLKPVS SDQQNRDEVA GKEIKEARRA SRLEDRLAGI
LAKAKARSVA VPVPTSEPAS PIPASSSTPE PTQSDAHKSA TPSSPPVETT WTSLKGLLGK
SKRSSNTSSS SSGRQTPDRP ISPATTAPAV AITPSAAAKL YDLERVDTAT PPISAVSTTE
LLYRGAPTPV PQDDTPLLVE PPKQPENQDQ DTQKTYVTSV ASAAASFLGS VVGGMGMAGG
LNQKQDEEES DIPSAQDGEI SRELDDVHAE DEEEEEQAEH SAIHTTPTPY DHVLNSDHAT
DYDSHSHYED GGDETSDDEE EEEEEEEEEE DAAQGTYDSM EGYDETEVVI VEEDDHSEHH
GDVDEDDREE DDYVEMREHM FPASAQDLNE YLQWG
//
