ID A0A0L0H9H3_SPIPD Unreviewed; 1423 AA.
AC A0A0L0H9H3;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Nucleoside diphosphate kinase {ECO:0000256|ARBA:ARBA00017632};
GN ORFNames=SPPG_06597 {ECO:0000313|EMBL:KNC98195.1};
OS Spizellomyces punctatus (strain DAOM BR117).
OC Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC Chytridiomycota incertae sedis; Chytridiomycetes; Spizellomycetales;
OC Spizellomycetaceae; Spizellomyces.
OX NCBI_TaxID=645134 {ECO:0000313|EMBL:KNC98195.1, ECO:0000313|Proteomes:UP000053201};
RN [1] {ECO:0000313|EMBL:KNC98195.1, ECO:0000313|Proteomes:UP000053201}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DAOM BR117 {ECO:0000313|EMBL:KNC98195.1,
RC ECO:0000313|Proteomes:UP000053201};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA Borenstein D., Chapman S., Chen Z., Engels R., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C.,
RA Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A.,
RA Saif S., Shenoy N., Sisk P., Stolte C., Sykes S., Thomson T., Walk T.,
RA White J., Yandava C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Lander E., Nusbaum C.;
RT "The Genome Sequence of Spizellomyces punctatus strain DAOM BR117.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the NDK family. {ECO:0000256|ARBA:ARBA00008142,
CC ECO:0000256|RuleBase:RU004011}.
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DR EMBL; KQ257461; KNC98195.1; -; Genomic_DNA.
DR RefSeq; XP_016606235.1; XM_016754798.1.
DR STRING; 645134.A0A0L0H9H3; -.
DR GeneID; 27689889; -.
DR VEuPathDB; FungiDB:SPPG_06597; -.
DR eggNOG; KOG0888; Eukaryota.
DR eggNOG; KOG0907; Eukaryota.
DR InParanoid; A0A0L0H9H3; -.
DR OrthoDB; 5481442at2759; -.
DR Proteomes; UP000053201; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004550; F:nucleoside diphosphate kinase activity; IEA:InterPro.
DR GO; GO:0006241; P:CTP biosynthetic process; IEA:InterPro.
DR GO; GO:0006183; P:GTP biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0006228; P:UTP biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 3.30.70.141; Nucleoside diphosphate kinase-like domain; 6.
DR InterPro; IPR034907; NDK-like_dom.
DR InterPro; IPR036850; NDK-like_dom_sf.
DR InterPro; IPR001564; Nucleoside_diP_kinase.
DR InterPro; IPR023005; Nucleoside_diP_kinase_AS.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR013766; Thioredoxin_domain.
DR PANTHER; PTHR46161; NUCLEOSIDE DIPHOSPHATE KINASE; 1.
DR PANTHER; PTHR46161:SF3; NUCLEOSIDE DIPHOSPHATE KINASE DDB_G0292928-RELATED; 1.
DR Pfam; PF00334; NDK; 6.
DR Pfam; PF00085; Thioredoxin; 1.
DR PRINTS; PR01243; NUCDPKINASE.
DR SMART; SM00562; NDK; 6.
DR SUPFAM; SSF54919; Nucleoside diphosphate kinase, NDK; 6.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS00469; NDP_KINASES; 4.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022840};
KW Reference proteome {ECO:0000313|Proteomes:UP000053201};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT SIGNAL 1..15
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 16..1423
FT /note="Nucleoside diphosphate kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012136058"
FT DOMAIN 278..418
FT /note="Nucleoside diphosphate kinase-like"
FT /evidence="ECO:0000259|SMART:SM00562"
FT DOMAIN 434..573
FT /note="Nucleoside diphosphate kinase-like"
FT /evidence="ECO:0000259|SMART:SM00562"
FT DOMAIN 616..755
FT /note="Nucleoside diphosphate kinase-like"
FT /evidence="ECO:0000259|SMART:SM00562"
FT DOMAIN 773..912
FT /note="Nucleoside diphosphate kinase-like"
FT /evidence="ECO:0000259|SMART:SM00562"
FT DOMAIN 957..1095
FT /note="Nucleoside diphosphate kinase-like"
FT /evidence="ECO:0000259|SMART:SM00562"
FT DOMAIN 1103..1243
FT /note="Nucleoside diphosphate kinase-like"
FT /evidence="ECO:0000259|SMART:SM00562"
FT REGION 66..87
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 257..277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 582..613
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1239..1423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1245..1325
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1423 AA; 154651 MW; BE2DBAADBEF19C3D CRC64;
MVRLVLLVFL FPLLALQLYN HREAACRVID SYIESSPLLT FVAHSSFAHW IAPCLAPGFV
KGPKQYLSSQ SSRHHSPDPD QAQLGGADQE DCIPCSQLQD PYSRGKPSQK DMSAHAKRVE
LQGTISVTTD AEWEALLSKP GLTVVDVYAK WAGPCEPMQN IFKRLKLDFG DEVTFVMAQT
DAIDVLSKFR DKSCPLFLFF FNGVLVKMVK GANAPMVEKV IKDQLELEEK RMPHIPLVLD
DLPNALTISN METESPISVT SQDALSPTSV VSPTTGPSEQ TLAIIKPEAM APGIVSSILD
IIRRNRFDIV KKKKCWLTPE QVEELYREHE KAPYFQGVLT HMSTAPVLAL VLAKDNAVQE
WRKIMGPANS GRARDDAPSS IRALHGTDNR LNAVYGSETP EAAQNEIELL FGSASAVFEI
PLTDRDITPT SGQPEKTLAI IKPDMIDGEK VDAIVERIVC RGYQVLKREN VHLSPDEAAE
LYSHQKEMPY FNDAVAFMAS GPVVALVLKG DDVIRGWREM IGPTDPEIAR REMPMSIRAV
FGTDPVRNAV HGAESADGAV REIGQLFPNV LMRTESAIFG TRPSTGAGAS RPDLAADAAA
KTTEHSTSQN DITSRTERTC ALIKPDAYAA GKKDEIVEKI KLAGFAIVAE KEVEMAREMA
EEFYKEHHGK PFYDELVAWM SSTPIYAMVL ENDTAITAWR ELAGPTNSIK AKEIAPESIR
ALYGTDGSHN AVHGSDSPGS AEREIRIIFG DSVRPFPAVN LASKTHLATR PLVERTLALI
KPDAFGSGKK DEIVNRIKEQ GFAIVRESEV QWTEDKAKEF YKEHEGKGFY DQLVGWMSSA
PIYAIVLEKE GAIAGWRELA GPTNSERARE MAPNSIRALY GKDGSHNAVH GSDSPQSAER
EIRIVFGDTV SPFPSVQGAK PAVAASGSVS VLAHTGPETQ DPIQPVNAQL NGDVRRLERT
LALIKPDAHS LHKEAILTRV QEAGFIIVKE SEIQFSPDMA KEFYKEHAGK GFYESLVEWM
SSAPVYAMVL EREDAIQAWR DLAGPTNAEK AREIAPNSIR ALFGTDGSKN AVHGSDSPSS
AAREIHVIFG DAVSPYPSGR PTLERTLALL KPDVASTTHK DEIISRIRQQ GFTILHEKEV
LLSRQRAMEF YKEHDGKPFY NELVEWMSSA PIYAMVLERE GAVLKWRELA GATDPAKAKE
TAPNSIRALY GSSQTHNAVH GSDSLASSAR EISILFPELG ASPSEPEPSD SSATNQNAKQ
TIVTPRPPAT TKPTASSPSR ASSTTNITRK STATLATRAA SQKSLAGTNS KPGSRVGSTT
ALDASRKAAV SKPASRAASK PSSRVASKQD LAGDAKKTRA SGLRSSTVAM DAEQDKGGEK
DALAAAFEPA GHVTTHPGEG MDKVPVEGDA GPGIMEDPTN VTV
//
