ID A0A0L0H9X6_SPIPD Unreviewed; 1502 AA.
AC A0A0L0H9X6;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=PXA domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SPPG_06974 {ECO:0000313|EMBL:KNC97987.1};
OS Spizellomyces punctatus (strain DAOM BR117).
OC Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC Chytridiomycota incertae sedis; Chytridiomycetes; Spizellomycetales;
OC Spizellomycetaceae; Spizellomyces.
OX NCBI_TaxID=645134 {ECO:0000313|EMBL:KNC97987.1, ECO:0000313|Proteomes:UP000053201};
RN [1] {ECO:0000313|EMBL:KNC97987.1, ECO:0000313|Proteomes:UP000053201}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DAOM BR117 {ECO:0000313|EMBL:KNC97987.1,
RC ECO:0000313|Proteomes:UP000053201};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA Borenstein D., Chapman S., Chen Z., Engels R., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C.,
RA Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A.,
RA Saif S., Shenoy N., Sisk P., Stolte C., Sykes S., Thomson T., Walk T.,
RA White J., Yandava C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Lander E., Nusbaum C.;
RT "The Genome Sequence of Spizellomyces punctatus strain DAOM BR117.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR EMBL; KQ257462; KNC97987.1; -; Genomic_DNA.
DR RefSeq; XP_016606027.1; XM_016755163.1.
DR STRING; 645134.A0A0L0H9X6; -.
DR GeneID; 27690237; -.
DR VEuPathDB; FungiDB:SPPG_06974; -.
DR eggNOG; KOG2101; Eukaryota.
DR InParanoid; A0A0L0H9X6; -.
DR OMA; ETHAHAY; -.
DR OrthoDB; 1333868at2759; -.
DR Proteomes; UP000053201; Unassembled WGS sequence.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd00030; C2; 1.
DR CDD; cd06093; PX_domain; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR013937; Sorting_nexin_C.
DR PANTHER; PTHR22775; SORTING NEXIN; 1.
DR PANTHER; PTHR22775:SF3; SORTING NEXIN-13; 1.
DR Pfam; PF00168; C2; 1.
DR Pfam; PF08628; Nexin_C; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF02194; PXA; 1.
DR Pfam; PF00615; RGS; 1.
DR SMART; SM00239; C2; 1.
DR SMART; SM00313; PXA; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS51207; PXA; 1.
DR PROSITE; PS50132; RGS; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000053201}.
FT DOMAIN 237..408
FT /note="PXA"
FT /evidence="ECO:0000259|PROSITE:PS51207"
FT DOMAIN 421..539
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 600..732
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT DOMAIN 1013..1125
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 1..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 572..594
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 742..851
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1180..1243
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1276..1334
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..46
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 573..594
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 742..768
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 771..796
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 832..847
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1188..1205
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1222..1236
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1276..1319
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1502 AA; 164002 MW; 331AD1C10E3F2970 CRC64;
MTEAVSQEAL TLDESLKHTA APVLNEAQNQ KARKEGNEES RTGHPDGVGH KVPFLTSEIA
QLGGRPDDLV QTTETTNGKP EPPAPAIENE PKPEPIEHMD PVVAIQGTDE GDSIPLLSTT
ARRVWRQRKL DWRTTVVTRW PWIRPYWERV EFGLSLLPPG WPEKLPILAI AFLFSPRLFA
VLCAISVATL LGYMWGVTSG KGSGGLPNTL SWDHRMDQDR GLEALKVPVD MSAFSVSPSV
HNALEQFCGH IVRDFINNWY SNINHSGSTD FPEAVHASVR HVFIKLGTST NEIRPTALAL
PVFQTIILHM REYRVFESSS LQLDEYLSRN PNSAFNLHRT KDQIFEHLRR LSMHLAVELL
PRGDRCSPMV FAFVQEILAT SVLLPIVEMC SDSDWINRQL LTFLRKSQAS AVAMASKQTG
STGSPQPGLW APSRKDSSGE QVYVKVVEAR RLPIADMYGL YCSLLCGTKV QRSRKINAES
NPMWMEEFRF DWDNDDANGG VDGIVVDLLE SRLIKDEIIG SVYVPMSQLP PNKFLKGWLP
IDTADTRFAG VTNAEILLEA IRIAPAAGHG AGTNSARGSS AAQGNENPNS GLSNEISDLT
AEDILVRNEG LVEFMQYMDD IKSSDYIQLY VMIDSFNRFA KLEMSSQSSS GLANAIEGLR
TDALSIFDTF FSPSASQRVD LESPELVERV RQAVLASPGA DVFRPLQQRI VEVTEKRFME
GFKHSQLYQR YLVENGLTLR ESQQKTGSAS GSGSSGSDSE SVASANNSIP PALPPRLPDV
SLPAPELPPR SVAEIPAVPP RPTVVTEGTS GKMSPSTDAT PTLPPRPPAQ TDDVKSNVSS
GQDAIPKSSW KGASDIDNEL FTDVLPLNDD TSTLEEPVPG TSGMQSAVEA QESVAATAAS
EIEDETDAMT ASIQSAAHVL ENLGKNGNHD IEEVKAAINT LREQVTLIDS IMRRSADAEK
LSDLASTKLQ LQTQVEELAD LIAQEEQQAK QGHLAVDLRN VRINILDMTA PEKDKDEKNI
FAFASTPTHP KSIVFIVQIE RTNGSGGWMI SKSYADIIAL NEALRTVFPK VRKSNFPQRT
RVTGTKAREE LSHELERWLN IIASDATLYE SAQVQDFMKP ENIQTQEYSA KPVVATKVLG
TLKSAGSILR KVAVATPMRA ATFVASEVNA AVAGVAHGMK KNEPTNSKTI RRSSSFWSNK
PAGSEEDQPE TLLVPARASS LDDAVSDHDE GSDKGLGTKP MVRNKSVGSL ASVTSHISAG
GSASVDASNA TVPVGSNASG DYSMSATSYR PETPPRSSSA RSASPAKSLA GSIKSVEGPS
GSGSPARHSR EDPPLSDAEL EIMLECVFGI IEEVFHLSDP NQWLRQKGLH MVKTILRRTY
GTSISTLIQS RLIEATTETK VASYVDMLDG SLWPEGIWYS TKAQQDGIPP TPRSEEDMAE
TKMEAKHLFI NSGLGGVETV ARVVGKYNTV AGMTRLFNML QHQDLNRHLV CMIMDRLVKS
IF
//
