ID A0A0L0HD68_SPIPD Unreviewed; 474 AA.
AC A0A0L0HD68;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=G-protein coupled receptors family 2 profile 2 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SPPG_06335 {ECO:0000313|EMBL:KNC98653.1};
OS Spizellomyces punctatus (strain DAOM BR117).
OC Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC Chytridiomycota incertae sedis; Chytridiomycetes; Spizellomycetales;
OC Spizellomycetaceae; Spizellomyces.
OX NCBI_TaxID=645134 {ECO:0000313|EMBL:KNC98653.1, ECO:0000313|Proteomes:UP000053201};
RN [1] {ECO:0000313|EMBL:KNC98653.1, ECO:0000313|Proteomes:UP000053201}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DAOM BR117 {ECO:0000313|EMBL:KNC98653.1,
RC ECO:0000313|Proteomes:UP000053201};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA Borenstein D., Chapman S., Chen Z., Engels R., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C.,
RA Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A.,
RA Saif S., Shenoy N., Sisk P., Stolte C., Sykes S., Thomson T., Walk T.,
RA White J., Yandava C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Lander E., Nusbaum C.;
RT "The Genome Sequence of Spizellomyces punctatus strain DAOM BR117.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor Fz/Smo family.
CC {ECO:0000256|ARBA:ARBA00008077}.
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DR EMBL; KQ257460; KNC98653.1; -; Genomic_DNA.
DR RefSeq; XP_016606693.1; XM_016754549.1.
DR AlphaFoldDB; A0A0L0HD68; -.
DR STRING; 645134.A0A0L0HD68; -.
DR GeneID; 27689651; -.
DR VEuPathDB; FungiDB:SPPG_06335; -.
DR eggNOG; ENOG502QWAA; Eukaryota.
DR InParanoid; A0A0L0HD68; -.
DR OMA; RMEIPYL; -.
DR OrthoDB; 1332706at2759; -.
DR Proteomes; UP000053201; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000539; Frizzled/Smoothened_7TM.
DR InterPro; IPR022343; GCR1-cAMP_receptor.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR022340; GPCR_GCR1_put.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR PANTHER; PTHR23112; G PROTEIN-COUPLED RECEPTOR 157-RELATED; 1.
DR PANTHER; PTHR23112:SF0; G-PROTEIN COUPLED RECEPTOR 157; 1.
DR Pfam; PF05462; Dicty_CAR; 1.
DR PRINTS; PR02001; GCR1CAMPR.
DR PRINTS; PR02000; GCR1PLANT.
DR SMART; SM01330; Frizzled; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
PE 3: Inferred from homology;
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000053201};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 24..46
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 58..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 131..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 22..295
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
FT DOMAIN 36..291
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT REGION 360..427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 360..379
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 380..396
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 413..427
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 474 AA; 53315 MW; A5B864D90DF38201 CRC64;
MSTTTPPPVS PPPFASAELQ SIQVAVRVAS CLSILGSCSI LGTYLLASRF KSITNRLVFY
MSVADLVASI MLSLGSFPIE HGSEAFCSAQ GFIIQTYIQA SMVWTLVMSM SIVFAVCKHR
PLRDFMRYEK YFHAAAWGLP LISSIVLQLL REDDKGPVFA PSVFWCWIGG KYTSYRMIFF
YGPLWTVFII NVLGYMTIGW IVWRGNRRLT SSLEVPFNRR GISIPSQRTS AAIKRYILKT
SFYLLAFFIN WLIPTVNRIQ NMADPTYPIY GLFILHAVSA PLQGFLNSVV YFWATPRFLR
FCRRSGRLNK PRRQDRTPRS VNVLTMATAL TGQIYDPAQP DKVNHTEAWV KSLPVAKTLT
QDSESASSTV TMKTDDSSTS KPGSKMKPRD EKVLFKHAPA TPPLPSALMN KYRPRSTERS
PSVNHNHVSR RATIALESET ADRPSSDWAE IVDALCEGLE GTHEEESIHE EIKV
//
