ID   A0A0L0HUF5_SPIPD        Unreviewed;       803 AA.
AC   A0A0L0HUF5;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   RecName: Full=Dynamin-type G domain-containing protein {ECO:0000259|PROSITE:PS51718};
GN   ORFNames=SPPG_00426 {ECO:0000313|EMBL:KND04717.1};
OS   Spizellomyces punctatus (strain DAOM BR117).
OC   Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC   Chytridiomycota incertae sedis; Chytridiomycetes; Spizellomycetales;
OC   Spizellomycetaceae; Spizellomyces.
OX   NCBI_TaxID=645134 {ECO:0000313|EMBL:KND04717.1, ECO:0000313|Proteomes:UP000053201};
RN   [1] {ECO:0000313|EMBL:KND04717.1, ECO:0000313|Proteomes:UP000053201}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DAOM BR117 {ECO:0000313|EMBL:KND04717.1,
RC   ECO:0000313|Proteomes:UP000053201};
RG   The Broad Institute Genome Sequencing Platform;
RA   Russ C., Cuomo C., Shea T., Young S.K., Zeng Q., Koehrsen M., Haas B.,
RA   Borodovsky M., Guigo R., Alvarado L., Berlin A., Bochicchio J.,
RA   Borenstein D., Chapman S., Chen Z., Engels R., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C.,
RA   Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A.,
RA   Saif S., Shenoy N., Sisk P., Stolte C., Sykes S., Thomson T., Walk T.,
RA   White J., Yandava C., Burger G., Gray M.W., Holland P.W.H., King N.,
RA   Lang F.B.F., Roger A.J., Ruiz-Trillo I., Lander E., Nusbaum C.;
RT   "The Genome Sequence of Spizellomyces punctatus strain DAOM BR117.";
RL   Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC         Evidence={ECO:0000256|ARBA:ARBA00001270};
CC   -!- SUBCELLULAR LOCATION: Mitochondrion outer membrane
CC       {ECO:0000256|ARBA:ARBA00004374}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004374}.
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DR   EMBL; KQ257450; KND04717.1; -; Genomic_DNA.
DR   RefSeq; XP_016612756.1; XM_016748753.1.
DR   AlphaFoldDB; A0A0L0HUF5; -.
DR   STRING; 645134.A0A0L0HUF5; -.
DR   GeneID; 27684154; -.
DR   VEuPathDB; FungiDB:SPPG_00426; -.
DR   eggNOG; KOG0448; Eukaryota.
DR   InParanoid; A0A0L0HUF5; -.
DR   OMA; THRITHG; -.
DR   OrthoDB; 1381184at2759; -.
DR   Proteomes; UP000053201; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0007005; P:mitochondrion organization; IEA:UniProt.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR045063; Dynamin_N.
DR   InterPro; IPR030381; G_DYNAMIN_dom.
DR   InterPro; IPR027094; Mitofusin_fam.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR10465; TRANSMEMBRANE GTPASE FZO1; 1.
DR   PANTHER; PTHR10465:SF0; TRANSMEMBRANE GTPASE MARF-RELATED; 1.
DR   Pfam; PF00350; Dynamin_N; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51718; G_DYNAMIN_2; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053201};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        682..699
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          191..467
FT                   /note="Dynamin-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51718"
FT   REGION          1..39
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          84..135
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        107..121
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   803 AA;  89798 MW;  A6A78301A695F7DF CRC64;
     MSQVYVTPEP APSDTPEATT TKQATHEPQF LKTDSAKSFS TTNGFGVDSG YGGEHSQAIF
     AEKRTRLLTL IAGTKGVLRD LVGPTGTVSH TLRYPSGALR KAFGSKPPTR RTSSTEDDSQ
     PPASPIPVAA EPPTDSVTQG LRVLQLDLKS YSFKGPASQI DSDDHSLISQ LLESKIIECR
     QHLDRLNARI SDTRSRVLVT GDLNAGKSTF VNAVLRREIV PDDQQPCTAL FAEVVDADQN
     DGVEEVHGIR DPIKYDRSDP TTFERFDFRN LRHVVEDNEE DYELLRIYCR DRRAKTHSLL
     HNGVVDISLI DSPGLNIDSI KTTALFSQQE EIDVIVFVVN AENHFTLSGR DFLTTAGKEK
     AYIFIVVNRF DQIRRKDRCR RDILEQIRQI SPATYDDADN LVHFVSAKEC LHHPEGADAA
     GTMVPDFHKM EEALRSFILE KRARSKLAPA KIYLHNLLSD VMDISQYNSL ASANTATQIM
     KDMKDSAPAY DRMVQIKEQV LDDIDKTIDE TGLLVQQHAQ QQLAQFTDHL DAFTEHVEWN
     GPLYVWQYAR DLRNRVYSIA ALRVRRCEEF ARDKAISCLK DIESVAATCM SVPPSIDVDV
     VTGAFEGDVG SAPGSKALAG NGSVAKIVPM DVAEFFDHID KAELAKEYVP SLGLIIGGLV
     GYKRMATQMW RAGMSGASTG RLAFAGLTIA GIGIFLYVLS DMKNSVERKV VRKMREHFTE
     VGFVESNVDR VAKGTRRVLR LAIWEFQNQF QRILTENQRK RENQMRSIEL ARADKAFYDD
     MAYRAAELVR EVDAIDLEEK MVV
//