ID A0A0L0K4R9_9ACTN Unreviewed; 849 AA.
AC A0A0L0K4R9;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Metallophosphoesterase {ECO:0000313|EMBL:KND32813.1};
GN ORFNames=IQ63_21935 {ECO:0000313|EMBL:KND32813.1};
OS Streptomyces acidiscabies.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=42234 {ECO:0000313|EMBL:KND32813.1, ECO:0000313|Proteomes:UP000037151};
RN [1] {ECO:0000313|Proteomes:UP000037151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCPPB 4445 {ECO:0000313|Proteomes:UP000037151};
RA Harrison J., Sapp M., Thwaites R., Studholme D.J.;
RT "Genome sequencing of plant-pathogenic Streptomyces species.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KND32813.1}.
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DR EMBL; JPPY01000132; KND32813.1; -; Genomic_DNA.
DR RefSeq; WP_050372159.1; NZ_KQ257822.1.
DR AlphaFoldDB; A0A0L0K4R9; -.
DR PATRIC; fig|42234.21.peg.4534; -.
DR OrthoDB; 9807890at2; -.
DR Proteomes; UP000037151; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR CDD; cd07423; MPP_Prp_like; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR041780; MPP_PrpE-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR024028; PNKP_bac.
DR InterPro; IPR032380; PNKP_ligase_dom.
DR NCBIfam; TIGR04075; bacter_Pnkp; 1.
DR PANTHER; PTHR12435:SF2; PROTEIN KTI12 HOMOLOG; 1.
DR PANTHER; PTHR12435; UNCHARACTERIZED; 1.
DR Pfam; PF13671; AAA_33; 1.
DR Pfam; PF00149; Metallophos; 1.
DR Pfam; PF16542; PNKP_ligase; 1.
DR SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000037151}.
FT DOMAIN 190..376
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT DOMAIN 466..844
FT /note="Polynucleotide kinase-phosphatase ligase"
FT /evidence="ECO:0000259|Pfam:PF16542"
SQ SEQUENCE 849 AA; 93545 MW; 3BE099CA4AB978F2 CRC64;
MTEQHTRGRE LPVTDLSLVV LVGASGSGKS TFAARHFKRT EIISSDFCRG LVSDDENDQS
ATKDAFDVLH YIAGKRLAAG RRTVVDATSV QPDARRQLVD LARKFDVLPI AIVLDVPEEV
CAERNASRSD RADMPRRVIK RHIGELRRSL RQLEREGFRK VHVLRGVAEI DAATVRTEKR
FNDLTHLTGP FDIVGDIHGC GSELESLLGK LGYVDGVHPQ GRTAVFVGDL VDRGPDSPGV
LRRVMSMVKS GNALCVPGNH ENKYGRHLKG RKVQHTHGLA ETIEQMAGES EEFVTEVRQF
IDGLVSHYVL DGGKLVVCHA GLPEHYHGRT SGRVRSHALY GETTGETDEF GLPVRYPWAE
DYRGSAAVVY GHTPVPEATW LNNTICLDTG AVFGGKLTAL RWPERELVDV PAEKVWYEPV
KPLRSEAPGG QDGRPLDLAD VYGRRIVTTR YEGSTRVSVR EENAAAALEV MSRFAIDPRL
LPYLPPTMAP TPTSHAEGYL EHPEEAFAQY AGGGVQRVVC EEKHMGSRAV VLVCRDAEAA
RKRFGVDGPT GSLYTRTGRP FFDDATVTEE ILGRVRAAAD AAGLWESLET EWLLLDAELM
PWSLKATGLL RSQYAAVGAA SGAVFPGVLD ALSQAAERGV DVGELLTRQR ERAADASAFT
DAYRRYCWPT EGLDGVRLAP FQFLAVQGRS LTALPHDEQL ALLDRLVEHD PTGLLQTTRR
LYVDTTDPES VKAGVDWWLE LTGAGGEGMV VKPLGAVVRD GEGRLVQPGV KVRGREYLRI
IYGPEYTRPD QLSRLRGRFL NHKCSLAIRE YVLGLEALDR LAEGEPLWRV HEPVFGVLAL
ESEPVDPRL
//
