ID A0A0L0K4S1_9ACTN Unreviewed; 744 AA.
AC A0A0L0K4S1;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Membrane protein {ECO:0000313|EMBL:KND33107.1};
GN ORFNames=IQ63_20490 {ECO:0000313|EMBL:KND33107.1};
OS Streptomyces acidiscabies.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=42234 {ECO:0000313|EMBL:KND33107.1, ECO:0000313|Proteomes:UP000037151};
RN [1] {ECO:0000313|Proteomes:UP000037151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCPPB 4445 {ECO:0000313|Proteomes:UP000037151};
RA Harrison J., Sapp M., Thwaites R., Studholme D.J.;
RT "Genome sequencing of plant-pathogenic Streptomyces species.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KND33107.1}.
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DR EMBL; JPPY01000129; KND33107.1; -; Genomic_DNA.
DR RefSeq; WP_050371961.1; NZ_KQ257822.1.
DR AlphaFoldDB; A0A0L0K4S1; -.
DR PATRIC; fig|42234.21.peg.4225; -.
DR OrthoDB; 7051771at2; -.
DR Proteomes; UP000037151; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000037151};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 14..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 277..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 302..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 523..542
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 549..570
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 590..614
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 635..656
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 662..682
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 178..327
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 718..744
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 744 AA; 79280 MW; EA4C8EDA4AFF2688 CRC64;
METLARWSFR HRRLVVVLWV VAVVAIAGLG RLIPADYRVS DSLPNTDSST ASELLQREFP
DQAGEVDSIV WKVTGGTVRD PDVRERMGRM LAAVDALPHV AGVQSPYETG GERAISANGR
IAFASVRFDQ NGDDLAKDTV LKVIDTAQEF ATPKVSVDLG GYAVAQATMT ISTSVSELVG
VLAAAVVLWL AFGSLLAVSL PLVCAIASVI PAVALIGMVS RVMTVPSFAS SLTILLNLGV
GIDYALFLVT RQRRGLLAGR SIEDALVETL RTAGRSVLFA GTVICLALLG LFSLGVDYLS
GMAAASVIGI LFTMAAALTL LPALLGFFGE RLFSRRERRR AEAGEGDRAP DSRGWIRWAH
LVERRPLVFA VAATLVTVVL ALPLLSLRLG FSDQGNDPPE QTTRQAYDAL SEGFGPGFNA
PLLAVVAADG RLSDKALRSV NDAMAATPGV ASVTPARVSP SGKVAVQQVF PKTSPQSERT
KKLLHHLRDD VTPEAVRGTG AAVYIGGFTA TEVDFTDTIS ARLPLFIGVV VLLGALLLLI
AFRSLLVAAL TAVMNLFAIG VCFGVIVAVF QWGWLSGVTG IGETGPIDAY LPVFLFAILF
GLSMDYQVFL LGRMHETWAH TRDSRRSVTL GQVETGRVIT VAAAIMVLVF LSFASGEREM
KLFGIGMGVT VLFDAFVIRT MLVPAVLHLA GRASWWLPGP LDRLLPRLEV AERETAAVPP
QEADLSVVAG PADSRPHGND DHTN
//
