ID A0A0L0LDZ0_9BACT Unreviewed; 161 AA.
AC A0A0L0LDZ0;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=phenylalanine--tRNA ligase {ECO:0000256|ARBA:ARBA00012814};
DE EC=6.1.1.20 {ECO:0000256|ARBA:ARBA00012814};
GN Name=pheS {ECO:0000313|EMBL:KND48194.1};
GN ORFNames=AB201_01190 {ECO:0000313|EMBL:KND48194.1};
OS Parcubacteria bacterium C7867-006.
OC Bacteria; Candidatus Parcubacteria.
OX NCBI_TaxID=1659200 {ECO:0000313|EMBL:KND48194.1, ECO:0000313|Proteomes:UP000037457};
RN [1] {ECO:0000313|EMBL:KND48194.1, ECO:0000313|Proteomes:UP000037457}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C7867-006 {ECO:0000313|EMBL:KND48194.1};
RX PubMed=26257709; DOI=10.3389/fmicb.2015.00713;
RA Nelson W.C., Stegen J.C.;
RT "The reduced genomes of Parcubacteria (OD1) contain signatures of a
RT symbiotic lifestyle.";
RL Front. Microbiol. 6:713-713(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) +
CC L-phenylalanyl-tRNA(Phe); Xref=Rhea:RHEA:19413, Rhea:RHEA-COMP:9668,
CC Rhea:RHEA-COMP:9699, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:58095, ChEBI:CHEBI:78442,
CC ChEBI:CHEBI:78531, ChEBI:CHEBI:456215; EC=6.1.1.20;
CC Evidence={ECO:0000256|ARBA:ARBA00000395};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KND48194.1}.
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DR EMBL; LFCP01000001; KND48194.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L0LDZ0; -.
DR STRING; 1659200.AB201_01190; -.
DR PATRIC; fig|1659200.3.peg.439; -.
DR Proteomes; UP000037457; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004826; F:phenylalanine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0000049; F:tRNA binding; IEA:InterPro.
DR GO; GO:0043039; P:tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00496; PheRS_alpha_core; 1.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR002319; Phenylalanyl-tRNA_Synthase.
DR PANTHER; PTHR11538:SF41; PHENYLALANINE--TRNA LIGASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11538; PHENYLALANYL-TRNA SYNTHETASE; 1.
DR Pfam; PF01409; tRNA-synt_2d; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 4: Predicted;
KW Aminoacyl-tRNA synthetase {ECO:0000313|EMBL:KND48194.1};
KW Ligase {ECO:0000313|EMBL:KND48194.1}.
FT DOMAIN 1..140
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
SQ SEQUENCE 161 AA; 18187 MW; D628CE23482F420E CRC64;
MEKNKPPIRI IAPGKVFRHE ATDATHEAQF YQLEGLVVGE NISVANLKWT LETMFEKLFG
KKMNIRLRPS YFPFVEPGFE MDMSCFKCEG RGCSTCKNTG WIEIGGSGMV HPKVLESAGV
DSKKYSGFAF GYGVDRIAML KYGIDDVRLL YQGDLRLVNQ F
//
