ID A0A0L0M8G6_9BURK Unreviewed; 595 AA.
AC A0A0L0M8G6;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=site-specific DNA-methyltransferase (adenine-specific) {ECO:0000256|ARBA:ARBA00011900};
DE EC=2.1.1.72 {ECO:0000256|ARBA:ARBA00011900};
GN ORFNames=BVER_03530 {ECO:0000313|EMBL:KND58566.1};
OS Candidatus Burkholderia verschuerenii.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia.
OX NCBI_TaxID=242163 {ECO:0000313|EMBL:KND58566.1, ECO:0000313|Proteomes:UP000036959};
RN [1] {ECO:0000313|Proteomes:UP000036959}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UZHbot4 {ECO:0000313|Proteomes:UP000036959};
RA Carlier A., Eberl L., Pinto-Carbo M.;
RT "Comparative genomics of Burkholderia leaf nodule symbionts.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an
CC N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-
CC homocysteine; Xref=Rhea:RHEA:15197, Rhea:RHEA-COMP:12418, Rhea:RHEA-
CC COMP:12419, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:90615, ChEBI:CHEBI:90616; EC=2.1.1.72;
CC Evidence={ECO:0000256|ARBA:ARBA00001279};
CC -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00006594}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KND58566.1}.
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DR EMBL; LFJJ01000177; KND58566.1; -; Genomic_DNA.
DR RefSeq; WP_050455292.1; NZ_LFJJ01000177.1.
DR AlphaFoldDB; A0A0L0M8G6; -.
DR PATRIC; fig|242163.4.peg.2217; -.
DR Proteomes; UP000036959; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0009007; F:site-specific DNA-methyltransferase (adenine-specific) activity; IEA:UniProtKB-EC.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR011639; MethylTrfase_TaqI-like_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR33841:SF1; ADENINE-SPECIFIC METHYLTRANSFERASE PGLX; 1.
DR PANTHER; PTHR33841; DNA METHYLTRANSFERASE YEEA-RELATED; 1.
DR Pfam; PF07669; Eco57I; 1.
DR PRINTS; PR00507; N12N6MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:KND58566.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000036959};
KW Restriction system {ECO:0000256|ARBA:ARBA00022747};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KND58566.1}.
FT DOMAIN 239..334
FT /note="Type II methyltransferase M.TaqI-like"
FT /evidence="ECO:0000259|Pfam:PF07669"
SQ SEQUENCE 595 AA; 65150 MW; 4B2A1071B015E63C CRC64;
MSNPARETWV DPAVDPLTRY AACKAMARGY AESRKTEKTR VSHARAFCTA VIVSYWATLC
KRHKTAMKVR PMPLAAPTLA IDVQRTAQGI GSLIAEFPVE DAGYLIGSIY TVMLPTALRS
QLGAYYTPPP LVTRLLDLAE QAGFDFTHGT AIDPACGGGA FLAPVALRMW QRDKGASPEW
TFRRIAKRLR GVEIDPFAAW MTRVLLEAAL MPLCIAAKRR LPDLVTVADA LRPEDFGAFD
LVIGNPPYGR VTLDEPMRNH YARSLYGHAN LYGLFTDLAL RLAKPDGVVA YLTPTSFLGG
QYFKALRQLL TDEMNPVALD FVADRDGVFD DVLQETLLTA YTRKRHDAAP VVSTLVPKGL
NAAKVERIGA VSLTATGDPW LLPRTAADAS FLTAIASMRT RLSDLGYTVS TGPLVWNRHK
AQLRTEAIDG ALPLIWAESV TPKGFVFSAD RRNHVPFIAV HDDQPHLIVR KSCVLVQRTT
SKEQNRRLLA ALLPQPYLDK TGGAVVENHL NMVVAPSIDI ARVKPSTIEA LLSTEAVDRA
FRCISGSVAV SAYELNALPL PSINQLIALE ELIDKAGSKR DIERAVAGYY GIVRP
//
