ID A0A0L0MFS7_9BURK Unreviewed; 422 AA.
AC A0A0L0MFS7;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=L-fuconate dehydratase {ECO:0000256|ARBA:ARBA00013142};
DE EC=4.2.1.68 {ECO:0000256|ARBA:ARBA00013142};
GN ORFNames=BVER_03132 {ECO:0000313|EMBL:KND61178.1};
OS Candidatus Burkholderia verschuerenii.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia.
OX NCBI_TaxID=242163 {ECO:0000313|EMBL:KND61178.1, ECO:0000313|Proteomes:UP000036959};
RN [1] {ECO:0000313|Proteomes:UP000036959}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UZHbot4 {ECO:0000313|Proteomes:UP000036959};
RA Carlier A., Eberl L., Pinto-Carbo M.;
RT "Comparative genomics of Burkholderia leaf nodule symbionts.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-fuconate = 2-dehydro-3-deoxy-L-fuconate + H2O;
CC Xref=Rhea:RHEA:22772, ChEBI:CHEBI:15377, ChEBI:CHEBI:21291,
CC ChEBI:CHEBI:37448; EC=4.2.1.68;
CC Evidence={ECO:0000256|ARBA:ARBA00001737};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KND61178.1}.
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DR EMBL; LFJJ01000030; KND61178.1; -; Genomic_DNA.
DR RefSeq; WP_050452924.1; NZ_LFJJ01000030.1.
DR AlphaFoldDB; A0A0L0MFS7; -.
DR PATRIC; fig|242163.4.peg.4327; -.
DR OrthoDB; 8609034at2; -.
DR Proteomes; UP000036959; Unassembled WGS sequence.
DR GO; GO:0050023; F:L-fuconate dehydratase activity; IEA:UniProtKB-EC.
DR GO; GO:0009063; P:amino acid catabolic process; IEA:InterPro.
DR GO; GO:0016052; P:carbohydrate catabolic process; IEA:InterPro.
DR CDD; cd03324; rTSbeta_L-fuconate_dehydratase; 1.
DR Gene3D; 3.20.20.120; Enolase-like C-terminal domain; 1.
DR Gene3D; 3.30.390.10; Enolase-like, N-terminal domain; 1.
DR InterPro; IPR036849; Enolase-like_C_sf.
DR InterPro; IPR029017; Enolase-like_N.
DR InterPro; IPR029065; Enolase_C-like.
DR InterPro; IPR034610; L-fuconate_dehydratase.
DR InterPro; IPR018110; Mandel_Rmase/mucon_lact_enz_CS.
DR InterPro; IPR013342; Mandelate_racemase_C.
DR InterPro; IPR013341; Mandelate_racemase_N_dom.
DR InterPro; IPR046945; RHMD-like.
DR PANTHER; PTHR13794; ENOLASE SUPERFAMILY, MANDELATE RACEMASE; 1.
DR PANTHER; PTHR13794:SF58; MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1; 1.
DR Pfam; PF13378; MR_MLE_C; 1.
DR Pfam; PF02746; MR_MLE_N; 1.
DR SFLD; SFLDF00111; L-fuconate_dehydratase; 1.
DR SFLD; SFLDG00179; mandelate_racemase; 1.
DR SMART; SM00922; MR_MLE; 1.
DR SUPFAM; SSF51604; Enolase C-terminal domain-like; 1.
DR SUPFAM; SSF54826; Enolase N-terminal domain-like; 1.
DR PROSITE; PS00909; MR_MLE_2; 1.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:KND61178.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000036959}.
FT DOMAIN 199..295
FT /note="Mandelate racemase/muconate lactonizing enzyme C-
FT terminal"
FT /evidence="ECO:0000259|SMART:SM00922"
SQ SEQUENCE 422 AA; 47202 MW; 8CC5689F9394A515 CRC64;
MTTITKLSVR DIRFPTSRSL DGSDAMNATP DYSATYVTLE TDASNGLVGH GLTFTIGRGN
EICVSAVNAL APLIVGRKLE DITSNMGAFW RAFTSDSQLR WIGPDKGAIH LATVAVVNAA
WDLWARSEGK PVWKLLADTT PEELVRCLDF RYVTDAITPY EAIAILERHA ATRGEREKEM
LAKGYPAYTT SAGWLGYDDD KIRRLAREGV AQGWTHFKQK VGGNLEEDVR RARILREEIG
PNSRLMMDAN QVWDVDEAIA NMRRLAEFDP WWIEEPTSPD DVLGHAAIRR RLGSIGVATD
EHYQNRVMFK QLLQAEAIDF CQIDSCRLGG LNEVIVVLLM AAKFGVPVCP HAGGVGLCEY
VQHISLFDYI CVSGSLDNRV LEYVDHLHEH FIDPVVIRNG RYMPPQRAGY SIEMKADTLD
RF
//
